| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0915682 |
| TXNRD1 | thioredoxin reductase 1 | 0.0832811 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0665965 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0538111 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0466357 |
| CENPF | centromere protein F, 350/400kDa | 0.045047 |
| POTEF | POTE ankyrin domain family, member F | 0.044909 |
| NUP58 | nucleoporin 58 | 0.0412215 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0370999 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0366759 |
| RTN4 | reticulon 4 | 0.0351917 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0346822 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0335375 |
| PCBP2 | poly(rC) binding protein 2 | 0.0323493 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0323093 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.030845 |
| MKI67 | marker of proliferation Ki-67 | 0.0302435 |
| YBX1 | Y box binding protein 1 | 0.0293846 |
| MATR3 | matrin 3 | 0.0284406 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0280365 |
| QKI | QKI, KH domain containing, RNA binding | 0.0271654 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0268258 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0262273 |
| NCKAP1 | NCK-associated protein 1 | 0.0261762 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.025969 |
| FOSL1 | FOS-like antigen 1 | 0.025761 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0252275 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.024769 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0241584 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0240301 |
| RLF | rearranged L-myc fusion | 0.0239742 |
| TPM3 | tropomyosin 3 | 0.0237171 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0236649 |
| RPL3 | ribosomal protein L3 | 0.0230324 |
| SPAG9 | sperm associated antigen 9 | 0.0229333 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0228962 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0226852 |
| TPX2 | TPX2, microtubule-associated | 0.0223608 |
| RNF145 | ring finger protein 145 | 0.022338 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0218922 |
| FOXJ3 | forkhead box J3 | 0.0218425 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0218316 |
| MSN | moesin | 0.0216946 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0214549 |
| NEK7 | NIMA-related kinase 7 | 0.020804 |
| ZNF292 | zinc finger protein 292 | 0.0206801 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.0205996 |
| SNX3 | sorting nexin 3 | 0.0205952 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.02051 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0204521 |
| CCNL1 | cyclin L1 | 0.0202415 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.020174 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0201087 |
| FTL | ferritin, light polypeptide | 0.0200493 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0199684 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0197412 |
| XPO1 | exportin 1 | 0.019688 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0196809 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0196724 |
| JMJD1C | jumonji domain containing 1C | 0.0195247 |
| SRPK2 | SRSF protein kinase 2 | 0.0195199 |
| ARRDC3 | arrestin domain containing 3 | 0.0194962 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0194021 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0193306 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0193288 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0193243 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0193055 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.01914 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0191235 |
| TNPO1 | transportin 1 | 0.0190012 |
| NBAS | neuroblastoma amplified sequence | 0.0189124 |
| ECT2 | epithelial cell transforming 2 | 0.0188787 |
| MTF2 | metal response element binding transcription factor 2 | 0.0188205 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0188049 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.018682 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0185472 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0185136 |
| KIF5B | kinesin family member 5B | 0.0184547 |
| TFG | TRK-fused gene | 0.0184232 |
| USP24 | ubiquitin specific peptidase 24 | 0.0184063 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0183099 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0182659 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0182558 |
| GOLGA4 | golgin A4 | 0.0182259 |
| UBC | ubiquitin C | 0.0181497 |
| MEMO1 | mediator of cell motility 1 | 0.017514 |
| USP3 | ubiquitin specific peptidase 3 | 0.0174677 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0174183 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0173953 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.017312 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0172955 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0171842 |
| CENPE | centromere protein E, 312kDa | 0.0171826 |
| CEP170 | centrosomal protein 170kDa | 0.0169262 |
| DIAPH3 | diaphanous-related formin 3 | 0.0169144 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0168289 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0168283 |
| ATP13A3 | ATPase type 13A3 | 0.0168245 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0167374 |
| TFRC | transferrin receptor | 0.0167144 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TP63 | tumor protein p63 | -0.212081 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.182913 |
| CD44 | CD44 molecule (Indian blood group) | -0.172284 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.158099 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.121524 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.119915 |
| HLA-B | major histocompatibility complex, class I, B | -0.119346 |
| DST | dystonin | -0.116382 |
| CADM2 | cell adhesion molecule 2 | -0.115309 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.113935 |
| MT2A | metallothionein 2A | -0.104178 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0940738 |
| VIM | vimentin | -0.0873025 |
| EHBP1 | EH domain binding protein 1 | -0.086117 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0757896 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0742687 |
| VCL | vinculin | -0.0737845 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0723941 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0688429 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0687589 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0666102 |
| TNS3 | tensin 3 | -0.0651528 |
| EPHA4 | EPH receptor A4 | -0.0640107 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0615202 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0592471 |
| RIGI | RNA sensor RIG-I | -0.058774 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0584743 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0584324 |
| EFNA5 | ephrin-A5 | -0.0571375 |
| PTMA | prothymosin, alpha | -0.057034 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0557799 |
| SP100 | SP100 nuclear antigen | -0.0526424 |
| RNF213 | ring finger protein 213 | -0.052486 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0521269 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0520069 |
| RPL35A | ribosomal protein L35a | -0.0512517 |
| CAPRIN2 | caprin family member 2 | -0.0501701 |
| PDE10A | phosphodiesterase 10A | -0.0498173 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0448337 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0425989 |
| RAD51B | RAD51 paralog B | -0.0422535 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0421181 |
| PLSCR1 | phospholipid scramblase 1 | -0.0420175 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0417294 |
| TMSB4X | thymosin beta 4, X-linked | -0.039748 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.039628 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0393225 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0378103 |
| DENND1A | DENN/MADD domain containing 1A | -0.0377193 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0376229 |
| DNER | delta/notch-like EGF repeat containing | -0.0376203 |
| PRELID2 | PRELI domain containing 2 | -0.0375795 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0372917 |
| RUNX1 | runt-related transcription factor 1 | -0.0368562 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0362873 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0361298 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0360457 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0358717 |
| MYOF | myoferlin | -0.0354358 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0343803 |
| EXOC4 | exocyst complex component 4 | -0.0335804 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.033384 |
| RPL26 | ribosomal protein L26 | -0.0332453 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0332243 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0327975 |
| ZNF217 | zinc finger protein 217 | -0.0326125 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0322863 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0320507 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0319258 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0317455 |
| TMSB10 | thymosin beta 10 | -0.0306636 |
| PMP22 | peripheral myelin protein 22 | -0.0302917 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0295915 |
| AEBP2 | AE binding protein 2 | -0.0294763 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0294728 |
| FBXO11 | F-box protein 11 | -0.0293682 |
| STK17A | serine/threonine kinase 17a | -0.0292493 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0292359 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0290285 |
| SMYD3 | SET and MYND domain containing 3 | -0.0284664 |
| INTS6 | integrator complex subunit 6 | -0.0284209 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0283079 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0278807 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0277682 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0277674 |
| MT1E | metallothionein 1E | -0.0275602 |
| RPLP1 | ribosomal protein, large, P1 | -0.0273558 |
| NEK10 | NIMA-related kinase 10 | -0.0273328 |
| TRIM56 | tripartite motif containing 56 | -0.0271477 |
| TGM2 | transglutaminase 2 | -0.0271104 |
| HDAC9 | histone deacetylase 9 | -0.0270299 |
| AHNAK | AHNAK nucleoprotein | -0.0269215 |
| RPS8 | ribosomal protein S8 | -0.0268105 |
| LOXL2 | lysyl oxidase-like 2 | -0.0267067 |
| CAVIN1 | caveolae associated protein 1 | -0.0265579 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0264133 |
| RPS24 | ribosomal protein S24 | -0.0263251 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0261787 |
| LDHA | lactate dehydrogenase A | -0.0261314 |
| SQSTM1 | sequestosome 1 | -0.0259706 |
