| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCBP2 | poly(rC) binding protein 2 | 0.0328214 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0292589 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0267052 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0262486 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0257231 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0255216 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0244909 |
| TXNRD1 | thioredoxin reductase 1 | 0.0214933 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0201243 |
| OGA | O-GlcNAcase | 0.0193483 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0180284 |
| KIF5B | kinesin family member 5B | 0.0168326 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0167342 |
| MKI67 | marker of proliferation Ki-67 | 0.0165219 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0164792 |
| SPAG9 | sperm associated antigen 9 | 0.0164305 |
| NAV2 | neuron navigator 2 | 0.0161088 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0159637 |
| YBX1 | Y box binding protein 1 | 0.0158479 |
| RUNX1 | runt-related transcription factor 1 | 0.0156835 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0156167 |
| CENPF | centromere protein F, 350/400kDa | 0.0154189 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.014681 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0144752 |
| USP3 | ubiquitin specific peptidase 3 | 0.0144178 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0143707 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0141367 |
| XPO1 | exportin 1 | 0.0140979 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0138206 |
| MT2A | metallothionein 2A | 0.0137719 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0134766 |
| RPL3 | ribosomal protein L3 | 0.0134717 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0134188 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0133132 |
| CENPE | centromere protein E, 312kDa | 0.0129732 |
| TPM3 | tropomyosin 3 | 0.0128863 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0128324 |
| RPS6 | ribosomal protein S6 | 0.0126113 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0125347 |
| PHIP | pleckstrin homology domain interacting protein | 0.0125027 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0125001 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0124761 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0123718 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0122636 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0122552 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0121379 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0119398 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0119166 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0119048 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0118807 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0114966 |
| ATP13A3 | ATPase type 13A3 | 0.0114825 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.011349 |
| FAM13A | family with sequence similarity 13, member A | 0.0111471 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0110873 |
| UBC | ubiquitin C | 0.0110444 |
| OTUD7B | OTU deubiquitinase 7B | 0.0108173 |
| ADM | adrenomedullin | 0.0107832 |
| TPX2 | TPX2, microtubule-associated | 0.0107801 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0105601 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0105264 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0104892 |
| NUP58 | nucleoporin 58 | 0.0104154 |
| CCNL1 | cyclin L1 | 0.0104121 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0103627 |
| ENAH | enabled homolog (Drosophila) | 0.0103249 |
| SET | SET nuclear proto-oncogene | 0.0102073 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0101017 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0100177 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00986614 |
| MATR3 | matrin 3 | 0.00966435 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.00961536 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0096147 |
| FLNA | filamin A, alpha | 0.00960272 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.00955279 |
| ARRDC3 | arrestin domain containing 3 | 0.00952589 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.00950358 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00943452 |
| PNN | pinin, desmosome associated protein | 0.00941734 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.00928092 |
| ACTG1 | actin gamma 1 | 0.00921501 |
| RAB21 | RAB21, member RAS oncogene family | 0.00913434 |
| RPS2 | ribosomal protein S2 | 0.00906307 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.00902612 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.00901441 |
| MIS18BP1 | MIS18 binding protein 1 | 0.00899255 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00892263 |
| MSN | moesin | 0.00888167 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.00886609 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.00877716 |
| NCKAP1 | NCK-associated protein 1 | 0.00874711 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0087432 |
| MYO6 | myosin VI | 0.00874225 |
| RPL5 | ribosomal protein L5 | 0.00862087 |
| RBM25 | RNA binding motif protein 25 | 0.00857654 |
| RPL4 | ribosomal protein L4 | 0.0085659 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.00855604 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.00845565 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.00845317 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.00844296 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.163415 |
| FN1 | fibronectin 1 | -0.105986 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0787112 |
| GPC6 | glypican 6 | -0.0668297 |
| LOX | lysyl oxidase | -0.0655804 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0655461 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0643708 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0630017 |
| DPYD | dihydropyrimidine dehydrogenase | -0.062492 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0598662 |
| CD44 | CD44 molecule (Indian blood group) | -0.0597731 |
| HMGA2 | high mobility group AT-hook 2 | -0.0560713 |
| FAM20C | family with sequence similarity 20, member C | -0.0547062 |
| GLCCI1 | glucocorticoid induced 1 | -0.0497318 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0472124 |
| DST | dystonin | -0.0446016 |
| VIM | vimentin | -0.0439606 |
| TMSB10 | thymosin beta 10 | -0.0438745 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0434465 |
| NRG1 | neuregulin 1 | -0.042379 |
| USP34 | ubiquitin specific peptidase 34 | -0.0412307 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0387745 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0386008 |
| RAI14 | retinoic acid induced 14 | -0.0384428 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0384235 |
| RAD51B | RAD51 paralog B | -0.038199 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0376903 |
| CDH13 | cadherin 13 | -0.0374987 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0363086 |
| ETV6 | ets variant 6 | -0.0351077 |
| SYT1 | synaptotagmin I | -0.0336966 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0333123 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0332909 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0330307 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0325798 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0325261 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0320262 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0317625 |
| MEF2A | myocyte enhancer factor 2A | -0.0312558 |
| MECOM | MDS1 and EVI1 complex locus | -0.0311691 |
| NTN4 | netrin 4 | -0.031049 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0300416 |
| HDLBP | high density lipoprotein binding protein | -0.0299031 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0298996 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0297761 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0296282 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0294649 |
| EFNA5 | ephrin-A5 | -0.0291183 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0284007 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0278718 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0266925 |
| FBN1 | fibrillin 1 | -0.0262087 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0261845 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0257343 |
| EHBP1 | EH domain binding protein 1 | -0.0257044 |
| OSMR | oncostatin M receptor | -0.0256962 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0254438 |
| VMP1 | vacuole membrane protein 1 | -0.0251685 |
| SEPTIN9 | septin 9 | -0.0251064 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.024579 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0245546 |
| NRP1 | neuropilin 1 | -0.0245265 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.024207 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0241851 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0240192 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0239316 |
| AOPEP | aminopeptidase O (putative) | -0.0232431 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0229007 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0228321 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0224482 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0223968 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0223536 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0221853 |
| PRKCA | protein kinase C, alpha | -0.0221286 |
| RAB1A | RAB1A, member RAS oncogene family | -0.021979 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0219711 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0219639 |
| EXOC4 | exocyst complex component 4 | -0.0218713 |
| EGR1 | early growth response 1 | -0.0216242 |
| VCL | vinculin | -0.0214574 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.021225 |
| MTSS1 | metastasis suppressor 1 | -0.021124 |
| CUX1 | cut-like homeobox 1 | -0.0210864 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0206971 |
| SUMF1 | sulfatase modifying factor 1 | -0.0206843 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0205543 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0204685 |
| RASAL2 | RAS protein activator like 2 | -0.0204362 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0204305 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0204059 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0200617 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0200414 |
| MYO9A | myosin IXA | -0.0199324 |
| ATXN1 | ataxin 1 | -0.0198354 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0197564 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0194573 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0193192 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0191367 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0188969 |
| ZNF804A | zinc finger protein 804A | -0.0188779 |
