| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.146677 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0871348 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0865301 |
| RTN4 | reticulon 4 | 0.0568636 |
| TPM3 | tropomyosin 3 | 0.0461225 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0456092 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0455087 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.043522 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0397797 |
| CCNL1 | cyclin L1 | 0.038792 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0387175 |
| TUBB | tubulin, beta class I | 0.0365854 |
| WDR43 | WD repeat domain 43 | 0.0360541 |
| CENPF | centromere protein F, 350/400kDa | 0.0344997 |
| YBX1 | Y box binding protein 1 | 0.0340983 |
| USP3 | ubiquitin specific peptidase 3 | 0.0330797 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0312849 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0307664 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0307074 |
| MKI67 | marker of proliferation Ki-67 | 0.0301207 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0292171 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0274973 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0270413 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0268328 |
| ZNF292 | zinc finger protein 292 | 0.026374 |
| RPL3 | ribosomal protein L3 | 0.0262179 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.026085 |
| PFN1 | profilin 1 | 0.025939 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0256405 |
| NUP58 | nucleoporin 58 | 0.0255563 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0253939 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.02509 |
| PCBP2 | poly(rC) binding protein 2 | 0.0246111 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0245152 |
| SPAG9 | sperm associated antigen 9 | 0.0232552 |
| TPX2 | TPX2, microtubule-associated | 0.0231913 |
| FGB | fibrinogen beta chain | 0.0228144 |
| YBX3 | Y box binding protein 3 | 0.0223746 |
| TMEM123 | transmembrane protein 123 | 0.021647 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0214813 |
| LDHB | lactate dehydrogenase B | 0.0207012 |
| SIN3A | SIN3 transcription regulator family member A | 0.0204065 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0200534 |
| POTEF | POTE ankyrin domain family, member F | 0.0198363 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0197947 |
| TUBA1B | tubulin, alpha 1b | 0.0197236 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0196627 |
| HDGF | hepatoma-derived growth factor | 0.0196611 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0194852 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0194257 |
| ENAH | enabled homolog (Drosophila) | 0.0193228 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0190122 |
| CHN1 | chimerin 1 | 0.0190086 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0187639 |
| FAM168A | family with sequence similarity 168, member A | 0.0186864 |
| XPO1 | exportin 1 | 0.0185412 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0184612 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0175377 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0174674 |
| RNF145 | ring finger protein 145 | 0.017293 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0172172 |
| NUP153 | nucleoporin 153kDa | 0.0172132 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0170568 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0170475 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0169368 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0167443 |
| UCK2 | uridine-cytidine kinase 2 | 0.0167064 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0166459 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0165776 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0165593 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0165377 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0164379 |
| PNN | pinin, desmosome associated protein | 0.0163125 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0162631 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0161887 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0161739 |
| ECT2 | epithelial cell transforming 2 | 0.0159888 |
| ENO1 | enolase 1, (alpha) | 0.0158689 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0158676 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0158407 |
| ANLN | anillin, actin binding protein | 0.0156851 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0156162 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0156037 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0155358 |
| CENPE | centromere protein E, 312kDa | 0.015464 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0153024 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0152864 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0152493 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0150405 |
| RPL4 | ribosomal protein L4 | 0.0149765 |
| NCKAP1 | NCK-associated protein 1 | 0.0149252 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.0147797 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0147776 |
| TES | testin LIM domain protein | 0.014748 |
| WBP11 | WW domain binding protein 11 | 0.0147304 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0146379 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.0145258 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0144763 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0144433 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0144272 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.243802 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.19403 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.148576 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.146943 |
| DOCK4 | dedicator of cytokinesis 4 | -0.115732 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.114664 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.108906 |
| CMIP | c-Maf inducing protein | -0.0845555 |
| DOCK5 | dedicator of cytokinesis 5 | -0.073781 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0716962 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0675348 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0672771 |
| EGFR | epidermal growth factor receptor | -0.06145 |
| FNDC3B | fibronectin type III domain containing 3B | -0.058985 |
| SVIL | supervillin | -0.0586279 |
| KYNU | kynureninase | -0.0582694 |
| AHNAK | AHNAK nucleoprotein | -0.056195 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0558541 |
| MT2A | metallothionein 2A | -0.0554173 |
| PYGL | phosphorylase, glycogen, liver | -0.0547258 |
| IER3 | immediate early response 3 | -0.0543654 |
| FMNL2 | formin-like 2 | -0.0543019 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0537669 |
| GLIS3 | GLIS family zinc finger 3 | -0.0522659 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0512924 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0497826 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0486153 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0484366 |
| BICC1 | BicC family RNA binding protein 1 | -0.0478207 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0478106 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0474421 |
| CAVIN1 | caveolae associated protein 1 | -0.047415 |
| DST | dystonin | -0.0463236 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.046255 |
| VCL | vinculin | -0.0459959 |
| FLNB | filamin B, beta | -0.0447976 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.043834 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0434959 |
| OSMR | oncostatin M receptor | -0.0433266 |
| TMSB10 | thymosin beta 10 | -0.0422299 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0415278 |
| ACTG1 | actin gamma 1 | -0.0412451 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.040735 |
| USP34 | ubiquitin specific peptidase 34 | -0.0404169 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0401571 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0399932 |
| EFNA5 | ephrin-A5 | -0.0395685 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0395507 |
| CUX1 | cut-like homeobox 1 | -0.0395078 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0392652 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0386426 |
| STC1 | stanniocalcin 1 | -0.038556 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0382663 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0380195 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.037522 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0371268 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0367951 |
| ATXN1 | ataxin 1 | -0.0366999 |
| EHBP1 | EH domain binding protein 1 | -0.0363293 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0359461 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0356235 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0354509 |
| RAD51B | RAD51 paralog B | -0.0353491 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0353393 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0350651 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0350228 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0346057 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0342559 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0339899 |
| MYO1E | myosin IE | -0.0335973 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0334524 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0333389 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0332234 |
| HLA-B | major histocompatibility complex, class I, B | -0.0327546 |
| CDK13 | cyclin-dependent kinase 13 | -0.0327367 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0323933 |
| NEGR1 | neuronal growth regulator 1 | -0.0323869 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0315056 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0314308 |
| NF1 | neurofibromin 1 | -0.0312406 |
| SNX14 | sorting nexin 14 | -0.0311935 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0308384 |
| PCNX4 | pecanex 4 | -0.0306354 |
| NEBL | nebulette | -0.0305228 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0304367 |
| HMGA2 | high mobility group AT-hook 2 | -0.0302486 |
| MYOF | myoferlin | -0.0298772 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0298521 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0297679 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0297474 |
| COPA | coatomer protein complex, subunit alpha | -0.0297064 |
| NUMB | numb homolog (Drosophila) | -0.0297045 |
| LDHA | lactate dehydrogenase A | -0.0296124 |
| SMAD2 | SMAD family member 2 | -0.0296093 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0292955 |
| UTRN | utrophin | -0.0292139 |
| FAM107B | family with sequence similarity 107, member B | -0.0290277 |
| ACTN1 | actinin, alpha 1 | -0.0285291 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0283863 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0282792 |
