| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.152666 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.107102 |
| MT2A | metallothionein 2A | 0.102471 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0903958 |
| HLA-B | major histocompatibility complex, class I, B | 0.0898953 |
| IGF2 | insulin-like growth factor 2 | 0.0863398 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0857633 |
| RPLP2 | ribosomal protein, large, P2 | 0.0821581 |
| FAM13A | family with sequence similarity 13, member A | 0.0806946 |
| CANX | calnexin | 0.0806015 |
| PTMA | prothymosin, alpha | 0.0745641 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0740192 |
| RPL5 | ribosomal protein L5 | 0.0692778 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0679036 |
| RPL38 | ribosomal protein L38 | 0.0666298 |
| EGFR | epidermal growth factor receptor | 0.0645047 |
| TMSB10 | thymosin beta 10 | 0.063687 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0632342 |
| RPS6 | ribosomal protein S6 | 0.060142 |
| NDRG1 | N-myc downstream regulated 1 | 0.0591598 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0589252 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0585143 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0569388 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0568749 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0566918 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0566776 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0565227 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0559671 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0557957 |
| SNX9 | sorting nexin 9 | 0.054988 |
| VIM | vimentin | 0.0546005 |
| RPL28 | ribosomal protein L28 | 0.0533796 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.052966 |
| RYBP | RING1 and YY1 binding protein | 0.0524954 |
| RPL23 | ribosomal protein L23 | 0.0524769 |
| STAG2 | stromal antigen 2 | 0.0523528 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0521658 |
| RPL34 | ribosomal protein L34 | 0.0519241 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0510998 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0507842 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0507841 |
| CTBP2 | C-terminal binding protein 2 | 0.0504022 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0502414 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0497731 |
| MYOF | myoferlin | 0.0495517 |
| CD63 | CD63 molecule | 0.0494224 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0479712 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.047776 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0474372 |
| RPL36A | ribosomal protein L36a | 0.0470059 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0465734 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0459953 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0456127 |
| DCP1A | decapping mRNA 1A | 0.0452384 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0451778 |
| RACK1 | receptor for activated C kinase 1 | 0.0450695 |
| RPL19 | ribosomal protein L19 | 0.0444856 |
| FNBP1 | formin binding protein 1 | 0.0435528 |
| CENPF | centromere protein F, 350/400kDa | 0.0434092 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0432356 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0428753 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0428144 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0425794 |
| CALR | calreticulin | 0.0425535 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0421939 |
| RPL9 | ribosomal protein L9 | 0.0421232 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.041833 |
| HELZ | helicase with zinc finger | 0.0417209 |
| YY1 | YY1 transcription factor | 0.0407487 |
| RPS5 | ribosomal protein S5 | 0.040572 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0405358 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.040271 |
| FAM162A | family with sequence similarity 162, member A | 0.04027 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0398642 |
| RPLP1 | ribosomal protein, large, P1 | 0.0393864 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0392812 |
| B2M | beta-2-microglobulin | 0.038932 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0384745 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0382811 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0378235 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0378124 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0377457 |
| USP3 | ubiquitin specific peptidase 3 | 0.0375592 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0372003 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0371984 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0368197 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0366851 |
| ZNF148 | zinc finger protein 148 | 0.0364447 |
| HIP1 | huntingtin interacting protein 1 | 0.0360157 |
| LOXL2 | lysyl oxidase-like 2 | 0.0357842 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0354147 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0354077 |
| ARRDC3 | arrestin domain containing 3 | 0.0352659 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0352203 |
| PTK2 | protein tyrosine kinase 2 | 0.0352154 |
| TXNRD1 | thioredoxin reductase 1 | 0.0351269 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0351177 |
| SET | SET nuclear proto-oncogene | 0.0350907 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0349196 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.034245 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.212003 |
| FN1 | fibronectin 1 | -0.123991 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.10299 |
| S100A9 | S100 calcium binding protein A9 | -0.0974254 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.095118 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0906971 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0900281 |
| EZR | ezrin | -0.0889823 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0874756 |
| ASPH | aspartate beta-hydroxylase | -0.0800552 |
| GPC6 | glypican 6 | -0.0796318 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0746728 |
| KRT17 | keratin 17, type I | -0.0735615 |
| EXT1 | exostosin glycosyltransferase 1 | -0.073268 |
| JMJD1C | jumonji domain containing 1C | -0.0729704 |
| KYNU | kynureninase | -0.0704857 |
| MYO1E | myosin IE | -0.065942 |
| THBS1 | thrombospondin 1 | -0.0656973 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0637765 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0634583 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0632741 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0618066 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0614731 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.061331 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0612402 |
| ERBIN | erbb2 interacting protein | -0.0597093 |
| GOLGB1 | golgin B1 | -0.0595387 |
| MED13L | mediator complex subunit 13-like | -0.0588826 |
| SIK3 | SIK family kinase 3 | -0.0587489 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0573296 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0556218 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0553315 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.0550074 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0549248 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0543455 |
| EXOC4 | exocyst complex component 4 | -0.0530478 |
| EFNA5 | ephrin-A5 | -0.0524539 |
| RCOR1 | REST corepressor 1 | -0.0521465 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0520523 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0517512 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0511665 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0510334 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0508109 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0505825 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0503168 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0501979 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0501103 |
| CADM2 | cell adhesion molecule 2 | -0.0497844 |
| RNF145 | ring finger protein 145 | -0.0495037 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0484812 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0484191 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0482164 |
| ABHD17C | abhydrolase domain containing 17C | -0.0477479 |
| DSPP | dentin sialophosphoprotein | -0.047645 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0472284 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0467093 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0462917 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0461708 |
| PARD3 | par-3 family cell polarity regulator | -0.0460119 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0442555 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0440776 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0433541 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0433371 |
| RORA | RAR-related orphan receptor A | -0.0432905 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0431067 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0430623 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0428183 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0426163 |
| GRAMD2B | GRAM domain containing 2B | -0.0424891 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0422438 |
| DIAPH1 | diaphanous-related formin 1 | -0.0421805 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0410776 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0407223 |
| CMIP | c-Maf inducing protein | -0.0406236 |
| RAB10 | RAB10, member RAS oncogene family | -0.0401463 |
| MSI2 | musashi RNA-binding protein 2 | -0.0399832 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.03989 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.0398726 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0390463 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.038661 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0383783 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0382959 |
| INTS6 | integrator complex subunit 6 | -0.0382706 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0380773 |
| ATOSA | atos homolog A | -0.0380768 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0372951 |
| RAI14 | retinoic acid induced 14 | -0.0372883 |
| SNX14 | sorting nexin 14 | -0.0371498 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0370127 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0368096 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0359383 |
| ENO1 | enolase 1, (alpha) | -0.0358214 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0353958 |
| ANXA2 | annexin A2 | -0.0349131 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.0348868 |
| PRKCA | protein kinase C, alpha | -0.03446 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0340575 |
| RPL35A | ribosomal protein L35a | -0.0339978 |
| RNF213 | ring finger protein 213 | -0.0339537 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0337912 |