| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.190916 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.155958 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.138323 |
| PTMA | prothymosin, alpha | 0.128154 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0871801 |
| UBC | ubiquitin C | 0.074102 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0732106 |
| CALR | calreticulin | 0.0699513 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0647911 |
| TMSB4X | thymosin beta 4, X-linked | 0.064104 |
| CANX | calnexin | 0.0576884 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0573612 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0523429 |
| ASPH | aspartate beta-hydroxylase | 0.0520257 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0452005 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0446613 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0436727 |
| FN1 | fibronectin 1 | 0.0433151 |
| GOLGA4 | golgin A4 | 0.0427483 |
| RPS6 | ribosomal protein S6 | 0.0414905 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0412329 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.040913 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0399805 |
| MKI67 | marker of proliferation Ki-67 | 0.039429 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0393494 |
| RACK1 | receptor for activated C kinase 1 | 0.0375476 |
| S100A6 | S100 calcium binding protein A6 | 0.0373221 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0372489 |
| HMGB2 | high mobility group box 2 | 0.0367001 |
| HDGF | hepatoma-derived growth factor | 0.0366531 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0359572 |
| CCNL1 | cyclin L1 | 0.0356462 |
| TPM3 | tropomyosin 3 | 0.0349788 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0349596 |
| RPS12 | ribosomal protein S12 | 0.0340391 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.03401 |
| RPS27A | ribosomal protein S27a | 0.0335142 |
| PAPOLA | poly(A) polymerase alpha | 0.0329407 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0327487 |
| CENPF | centromere protein F, 350/400kDa | 0.0326661 |
| TUBA1B | tubulin, alpha 1b | 0.0323262 |
| SET | SET nuclear proto-oncogene | 0.0321251 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0319984 |
| PEG10 | paternally expressed 10 | 0.0308904 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0305288 |
| MATR3 | matrin 3 | 0.0303242 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0295136 |
| TXNRD1 | thioredoxin reductase 1 | 0.0292104 |
| NUP58 | nucleoporin 58 | 0.0290949 |
| RPS3 | ribosomal protein S3 | 0.0289925 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0272996 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0271145 |
| RPL11 | ribosomal protein L11 | 0.0269229 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0267459 |
| RPL23 | ribosomal protein L23 | 0.0267392 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0263981 |
| RPL12 | ribosomal protein L12 | 0.0261409 |
| RAD21 | RAD21 homolog (S. pombe) | 0.026084 |
| FAM13A | family with sequence similarity 13, member A | 0.0260838 |
| TOP1 | topoisomerase (DNA) I | 0.0258372 |
| RPLP0 | ribosomal protein, large, P0 | 0.0255787 |
| RPL5 | ribosomal protein L5 | 0.0255419 |
| RPLP2 | ribosomal protein, large, P2 | 0.0253875 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0252375 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0249582 |
| RPL3 | ribosomal protein L3 | 0.0248838 |
| RPS3A | ribosomal protein S3A | 0.024627 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0245318 |
| NCKAP1 | NCK-associated protein 1 | 0.0243544 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.024068 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0240401 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0239229 |
| RPS8 | ribosomal protein S8 | 0.0238334 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0232482 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0231764 |
| RPL4 | ribosomal protein L4 | 0.0230843 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0230382 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0227894 |
| AREG | amphiregulin | 0.0227857 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.022745 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0227301 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0227192 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0224158 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.022242 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0221535 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0219834 |
| RPL38 | ribosomal protein L38 | 0.0219255 |
| DSTN | destrin (actin depolymerizing factor) | 0.0216885 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0215603 |
| CLINT1 | clathrin interactor 1 | 0.0214537 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0213955 |
| RPL26 | ribosomal protein L26 | 0.0208592 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.020556 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0203531 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0203061 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0201377 |
| KRT18 | keratin 18, type I | 0.020012 |
| XPOT | exportin, tRNA | 0.0199049 |
| TPX2 | TPX2, microtubule-associated | 0.0197863 |
| RPL19 | ribosomal protein L19 | 0.0195066 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.211344 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.198773 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.17638 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.133906 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.125481 |
| ACTG1 | actin gamma 1 | -0.124483 |
| EXT1 | exostosin glycosyltransferase 1 | -0.116572 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.110717 |
| FTL | ferritin, light polypeptide | -0.105664 |
| POTEF | POTE ankyrin domain family, member F | -0.0959817 |
| MT2A | metallothionein 2A | -0.0852912 |
| HMGA1 | high mobility group AT-hook 1 | -0.0838212 |
| EFNA5 | ephrin-A5 | -0.0820545 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0752557 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0679831 |
| TMSB10 | thymosin beta 10 | -0.0662916 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0636454 |
| FNDC3B | fibronectin type III domain containing 3B | -0.063052 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0602451 |
| ERBIN | erbb2 interacting protein | -0.0598977 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0598314 |
| LDHA | lactate dehydrogenase A | -0.0597933 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.058192 |
| RCOR1 | REST corepressor 1 | -0.0571251 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0542805 |
| NAV2 | neuron navigator 2 | -0.0497171 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0485261 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0478807 |
| VCL | vinculin | -0.0470503 |
| MYO1E | myosin IE | -0.0469024 |
| ANXA2 | annexin A2 | -0.0450523 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0445447 |
| LAMB3 | laminin, beta 3 | -0.043556 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0425125 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0422686 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0416362 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0412989 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0411169 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0410683 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0410495 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0395733 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0388989 |
| SMAD3 | SMAD family member 3 | -0.0386788 |
| RAI14 | retinoic acid induced 14 | -0.0384021 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0380968 |
| FBXO32 | F-box protein 32 | -0.0380497 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0376215 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0374502 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0372549 |
| PTK2 | protein tyrosine kinase 2 | -0.036067 |
| RAD51B | RAD51 paralog B | -0.0359971 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0358482 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.035804 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0355651 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0352844 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0350707 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0349376 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0347477 |
| FNIP1 | folliculin interacting protein 1 | -0.0344321 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0342061 |
| ATXN1 | ataxin 1 | -0.0339695 |
| RUNX1 | runt-related transcription factor 1 | -0.0338298 |
| PKM | pyruvate kinase, muscle | -0.0337679 |
| RNF213 | ring finger protein 213 | -0.0326584 |
| ATP11A | ATPase, class VI, type 11A | -0.0325393 |
| PRKCA | protein kinase C, alpha | -0.0317273 |
| FHIT | fragile histidine triad | -0.0315135 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0313629 |
| SDC4 | syndecan 4 | -0.0312898 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0312235 |
| AFF1 | AF4/FMR2 family, member 1 | -0.030805 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0307564 |
| EGR1 | early growth response 1 | -0.0305022 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0305008 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0304307 |
| RPLP1 | ribosomal protein, large, P1 | -0.0298456 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0297278 |
| RIGI | RNA sensor RIG-I | -0.0296055 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0293793 |
| BBX | bobby sox homolog (Drosophila) | -0.0293482 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0292973 |
| ETV6 | ets variant 6 | -0.0292468 |
| FLNB | filamin B, beta | -0.0289297 |
| PALLD | palladin, cytoskeletal associated protein | -0.0287889 |
| FBXO34 | F-box protein 34 | -0.0286981 |
| RPL35A | ribosomal protein L35a | -0.0284417 |
| MCU | mitochondrial calcium uniporter | -0.028234 |
| CTBP2 | C-terminal binding protein 2 | -0.0279876 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0276854 |
| TAPBP | TAP binding protein (tapasin) | -0.0276784 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0276376 |
| TXNIP | thioredoxin interacting protein | -0.0274789 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0274683 |
| MX2 | MX dynamin-like GTPase 2 | -0.0271151 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0268338 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0267681 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0264952 |
| MAP1B | microtubule-associated protein 1B | -0.026359 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0263395 |
| TJP1 | tight junction protein 1 | -0.0262931 |
