| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.0864252 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0684754 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0594548 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0535356 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0516536 |
| SPAG9 | sperm associated antigen 9 | 0.0479831 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0478719 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0447833 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0424015 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0419668 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0391288 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0374298 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0372316 |
| TPM3 | tropomyosin 3 | 0.0366978 |
| AUTS2 | autism susceptibility candidate 2 | 0.0353313 |
| CTSL | cathepsin L | 0.0331225 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0310339 |
| UNC5D | unc-5 homolog D (C. elegans) | 0.0303866 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0295563 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0288963 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0272376 |
| DENND1A | DENN/MADD domain containing 1A | 0.0270568 |
| PCBP2 | poly(rC) binding protein 2 | 0.0264163 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0260414 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0259275 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0259244 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0258468 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0257727 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0250705 |
| FAM13A | family with sequence similarity 13, member A | 0.0247247 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0246919 |
| RYR2 | ryanodine receptor 2 (cardiac) | 0.0243026 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.024148 |
| SRPK2 | SRSF protein kinase 2 | 0.0240988 |
| CTBP2 | C-terminal binding protein 2 | 0.0238095 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0238019 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0226901 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0225178 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0221334 |
| MSN | moesin | 0.0213486 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0212905 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0212882 |
| NCKAP1 | NCK-associated protein 1 | 0.0212556 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0211039 |
| RUNX1 | runt-related transcription factor 1 | 0.0207933 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0205268 |
| NUP58 | nucleoporin 58 | 0.0203346 |
| BBX | bobby sox homolog (Drosophila) | 0.0202012 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0196281 |
| CANX | calnexin | 0.0194639 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0193944 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0191374 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0190083 |
| NBEAL1 | neurobeachin-like 1 | 0.0189506 |
| PTK2 | protein tyrosine kinase 2 | 0.0187927 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0185526 |
| PRELID2 | PRELI domain containing 2 | 0.0185067 |
| FSTL4 | follistatin-like 4 | 0.0184561 |
| RPL3 | ribosomal protein L3 | 0.0183939 |
| RAD51B | RAD51 paralog B | 0.0182531 |
| CPNE8 | copine VIII | 0.0179836 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0176972 |
| ZNF292 | zinc finger protein 292 | 0.0174669 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0174306 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0173743 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0171809 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0169481 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0169161 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0166969 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0162241 |
| ENO1 | enolase 1, (alpha) | 0.0162149 |
| SFTPA2 | surfactant protein A2 | 0.0161894 |
| SLK | STE20-like kinase | 0.0160029 |
| NCKAP5 | NCK-associated protein 5 | 0.0158966 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0158566 |
| PCDH9 | protocadherin 9 | 0.015742 |
| FLNA | filamin A, alpha | 0.0156416 |
| USP3 | ubiquitin specific peptidase 3 | 0.0155774 |
| TMEM178B | transmembrane protein 178B | 0.0154708 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0153444 |
| MYO1B | myosin IB | 0.015309 |
| CADM2 | cell adhesion molecule 2 | 0.0152305 |
| QKI | QKI, KH domain containing, RNA binding | 0.0149943 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0149716 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0149072 |
| XYLT1 | xylosyltransferase I | 0.0147867 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0146502 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0146335 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0145939 |
| FNIP1 | folliculin interacting protein 1 | 0.0145849 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0145677 |
| RCOR1 | REST corepressor 1 | 0.0145008 |
| DNER | delta/notch-like EGF repeat containing | 0.0144864 |
| APP | amyloid beta (A4) precursor protein | 0.0144332 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.014294 |
| NOCT | nocturnin | 0.0142638 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0142071 |
| DTNA | dystrobrevin, alpha | 0.0141831 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.014173 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.014066 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.219316 |
| GDA | guanine deaminase | -0.189864 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.164686 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.153592 |
| KYNU | kynureninase | -0.142864 |
| EFNA5 | ephrin-A5 | -0.133 |
| PDLIM5 | PDZ and LIM domain 5 | -0.122262 |
| ASPH | aspartate beta-hydroxylase | -0.11838 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.110613 |
| MYOF | myoferlin | -0.0957079 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0928035 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0879316 |
| DST | dystonin | -0.0872546 |
| PDE10A | phosphodiesterase 10A | -0.080851 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0807876 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0800843 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0777194 |
| COL5A2 | collagen, type V, alpha 2 | -0.075856 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0710132 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0698845 |
| FTL | ferritin, light polypeptide | -0.0689706 |
| NEK7 | NIMA-related kinase 7 | -0.0688294 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0675523 |
| VCL | vinculin | -0.0672331 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0636501 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0635234 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0627962 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0608635 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0599453 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0582352 |
| TMSB10 | thymosin beta 10 | -0.0579804 |
| CTSC | cathepsin C | -0.0567158 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0561857 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0557017 |
| NRCAM | neuronal cell adhesion molecule | -0.055292 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0547586 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0541704 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0526277 |
| DOCK4 | dedicator of cytokinesis 4 | -0.051951 |
| RPL12 | ribosomal protein L12 | -0.0514167 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0500036 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0496047 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0492219 |
| RPLP1 | ribosomal protein, large, P1 | -0.0481384 |
| LDHA | lactate dehydrogenase A | -0.0479601 |
| SMYD3 | SET and MYND domain containing 3 | -0.0477695 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0477519 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.044972 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0445183 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0442948 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.042214 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0400044 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0397039 |
| PCBP3 | poly(rC) binding protein 3 | -0.0396507 |
| ENAH | enabled homolog (Drosophila) | -0.0394484 |
| TGFBR1 | transforming growth factor, beta receptor 1 | -0.0392931 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0388744 |
| RTN1 | reticulon 1 | -0.0383048 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.038281 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0380822 |
| RPL26 | ribosomal protein L26 | -0.0378605 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0375576 |
| OSMR | oncostatin M receptor | -0.0371628 |
| NTN4 | netrin 4 | -0.0367356 |
| INHBA | inhibin, beta A | -0.0362449 |
| CD109 | CD109 molecule | -0.0355649 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0350865 |
| RPLP0 | ribosomal protein, large, P0 | -0.0348874 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0340834 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0338218 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0336521 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0328771 |
| MT2A | metallothionein 2A | -0.0327264 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0320607 |
| RPS12 | ribosomal protein S12 | -0.0309873 |
| RPL23 | ribosomal protein L23 | -0.0304927 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0302629 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0301318 |
| BMERB1 | bMERB domain containing 1 | -0.0300969 |
| RGS2 | regulator of G-protein signaling 2 | -0.0299464 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0297335 |
| RPL31 | ribosomal protein L31 | -0.0295068 |
| RPL19 | ribosomal protein L19 | -0.0291036 |
| PALLD | palladin, cytoskeletal associated protein | -0.0290358 |
| RPL37A | ribosomal protein L37a | -0.0289529 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0286726 |
| CDK6 | cyclin-dependent kinase 6 | -0.0285273 |
| RPS24 | ribosomal protein S24 | -0.0283845 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0282086 |
| RPS3 | ribosomal protein S3 | -0.0274374 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0273986 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0271699 |
| RPS4X | ribosomal protein S4, X-linked | -0.0271369 |
| ATAD1 | ATPase family, AAA domain containing 1 | -0.0265789 |
| EPHA4 | EPH receptor A4 | -0.0265639 |
| STC1 | stanniocalcin 1 | -0.0262012 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0259997 |
| MFF | mitochondrial fission factor | -0.0256694 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.0256313 |
| GRAMD1B | GRAM domain containing 1B | -0.0252373 |
