| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GOLGA4 | golgin A4 | 0.102463 |
| STC1 | stanniocalcin 1 | 0.098709 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0932574 |
| INHBA | inhibin, beta A | 0.0912343 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0899958 |
| RPS4X | ribosomal protein S4, X-linked | 0.0884307 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0871447 |
| OGA | O-GlcNAcase | 0.0860933 |
| RPS16 | ribosomal protein S16 | 0.082775 |
| SYT1 | synaptotagmin I | 0.0811837 |
| RPL13A | ribosomal protein L13a | 0.0753268 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0746801 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.073399 |
| TPM3 | tropomyosin 3 | 0.0711008 |
| CANX | calnexin | 0.0691067 |
| DTNA | dystrobrevin, alpha | 0.0681421 |
| HM13 | histocompatibility (minor) 13 | 0.0678651 |
| HELZ | helicase with zinc finger | 0.0663152 |
| FTL | ferritin, light polypeptide | 0.0645155 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0632188 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0631255 |
| VMP1 | vacuole membrane protein 1 | 0.0595432 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0593656 |
| MYOF | myoferlin | 0.0592783 |
| RTN4 | reticulon 4 | 0.0581689 |
| LDHA | lactate dehydrogenase A | 0.0575485 |
| H1-0 | H1.0 linker histone | 0.0554026 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0546983 |
| CCNY | cyclin Y | 0.0538729 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0536396 |
| PTK2 | protein tyrosine kinase 2 | 0.050748 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0507387 |
| RHEB | Ras homolog enriched in brain | 0.0503165 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.049926 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0489962 |
| ACTN4 | actinin, alpha 4 | 0.0489777 |
| YAP1 | Yes-associated protein 1 | 0.0480486 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0473485 |
| RPL12 | ribosomal protein L12 | 0.0459789 |
| RPL23 | ribosomal protein L23 | 0.0459348 |
| PKM | pyruvate kinase, muscle | 0.045895 |
| RPL35A | ribosomal protein L35a | 0.044843 |
| RPL11 | ribosomal protein L11 | 0.0445842 |
| TPD52 | tumor protein D52 | 0.0433404 |
| NDRG1 | N-myc downstream regulated 1 | 0.0433296 |
| RPL5 | ribosomal protein L5 | 0.04246 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0424117 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0421501 |
| MAP4 | microtubule-associated protein 4 | 0.0413958 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0412199 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0407876 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0405617 |
| USP3 | ubiquitin specific peptidase 3 | 0.0403274 |
| SPAG9 | sperm associated antigen 9 | 0.0400539 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0397553 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0395914 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0393449 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0393265 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0389967 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0389734 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0388399 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.038304 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0378851 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0376182 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0372824 |
| EZR | ezrin | 0.0366792 |
| RPS19 | ribosomal protein S19 | 0.0365704 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0364959 |
| RPL37 | ribosomal protein L37 | 0.0359337 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0348553 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0342914 |
| FLNB | filamin B, beta | 0.033965 |
| MEF2A | myocyte enhancer factor 2A | 0.032948 |
| SRPK2 | SRSF protein kinase 2 | 0.0328601 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0327735 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0326696 |
| TFG | TRK-fused gene | 0.0317813 |
| PGK1 | phosphoglycerate kinase 1 | 0.0315513 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0304996 |
| RBM39 | RNA binding motif protein 39 | 0.0278938 |
| TOP1 | topoisomerase (DNA) I | 0.0277035 |
| TXNRD1 | thioredoxin reductase 1 | 0.0273821 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.027326 |
| ACTG1 | actin gamma 1 | 0.0272618 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0264277 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.02642 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.025088 |
| RPL9 | ribosomal protein L9 | 0.0249438 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0247778 |
| PDE10A | phosphodiesterase 10A | 0.0245248 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.023008 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0222347 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.022127 |
| DST | dystonin | 0.0207378 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0204569 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0203774 |
| RORA | RAR-related orphan receptor A | 0.0201728 |
| CCNL1 | cyclin L1 | 0.0195108 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0177233 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0173791 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.18584 |
| PRKCA | protein kinase C, alpha | -0.155082 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.140359 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.132519 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.112267 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.112052 |
| FNDC3B | fibronectin type III domain containing 3B | -0.105153 |
| SLTM | SAFB-like, transcription modulator | -0.0994763 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0945964 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0934926 |
| TMSB10 | thymosin beta 10 | -0.0869323 |
| ITGA6 | integrin, alpha 6 | -0.083022 |
| LMO7 | LIM domain 7 | -0.0742667 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0703218 |
| NHSL1 | NHS-like 1 | -0.0693393 |
| ATP11A | ATPase, class VI, type 11A | -0.0683798 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.067786 |
| FN1 | fibronectin 1 | -0.0676799 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0665227 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0660595 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0660458 |
| ASPH | aspartate beta-hydroxylase | -0.0657297 |
| PTMA | prothymosin, alpha | -0.06532 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0646943 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0629981 |
| TXNIP | thioredoxin interacting protein | -0.0627522 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0620778 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0618136 |
| MCL1 | myeloid cell leukemia 1 | -0.0615873 |
| IGF2 | insulin-like growth factor 2 | -0.0604478 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0578001 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.057731 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0571419 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0560787 |
| MYO10 | myosin X | -0.0540441 |
| FOXP1 | forkhead box P1 | -0.0537874 |
| OSMR | oncostatin M receptor | -0.0532377 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0526844 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0523897 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0520463 |
| B2M | beta-2-microglobulin | -0.0505182 |
| UBAC2 | UBA domain containing 2 | -0.0504325 |
| MYO1E | myosin IE | -0.0495717 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0490526 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0488876 |
| RPL37A | ribosomal protein L37a | -0.0488353 |
| SMYD3 | SET and MYND domain containing 3 | -0.0484693 |
| NFIA | nuclear factor I/A | -0.0481397 |
| RAD51B | RAD51 paralog B | -0.0477914 |
| FMNL2 | formin-like 2 | -0.0467036 |
| ANXA2 | annexin A2 | -0.0453712 |
| HMGA2 | high mobility group AT-hook 2 | -0.0430421 |
| RPLP1 | ribosomal protein, large, P1 | -0.0427377 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0426313 |
| ATXN1 | ataxin 1 | -0.0414136 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0413155 |
| PDE8A | phosphodiesterase 8A | -0.0398793 |
| MT2A | metallothionein 2A | -0.0394569 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0387191 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0380342 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.037433 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.037364 |
| SMAD3 | SMAD family member 3 | -0.0373368 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0372384 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0371782 |
| MED13L | mediator complex subunit 13-like | -0.0353734 |
| GPC6 | glypican 6 | -0.0348637 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0346455 |
| ENO1 | enolase 1, (alpha) | -0.0327104 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0319897 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0319511 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0310118 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0297857 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0293974 |
| PARD3 | par-3 family cell polarity regulator | -0.0291704 |
| RAB10 | RAB10, member RAS oncogene family | -0.0290161 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0288966 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0281679 |
| EXOC6B | exocyst complex component 6B | -0.0277161 |
| VIM | vimentin | -0.0275051 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0270497 |
| RPL34 | ribosomal protein L34 | -0.0267626 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0256077 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0253875 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0247517 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0230956 |
| CD44 | CD44 molecule (Indian blood group) | -0.0218013 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0216278 |
| RSF1 | remodeling and spacing factor 1 | -0.0204469 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0202945 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0202253 |
| RPS8 | ribosomal protein S8 | -0.020195 |
| KYNU | kynureninase | -0.0197626 |
| GSK3B | glycogen synthase kinase 3 beta | -0.017707 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0168626 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0164478 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0161326 |
| JMJD1C | jumonji domain containing 1C | -0.0156141 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0150806 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0145048 |
