| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0949368 |
| MKI67 | marker of proliferation Ki-67 | 0.078168 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0751109 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0696751 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0663488 |
| CENPF | centromere protein F, 350/400kDa | 0.0624256 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0524673 |
| TMSB4X | thymosin beta 4, X-linked | 0.0518392 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0509518 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0424663 |
| PTMA | prothymosin, alpha | 0.0408487 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0354672 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.035006 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0333396 |
| CENPE | centromere protein E, 312kDa | 0.0316917 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.028686 |
| H1-4 | H1.4 linker histone, cluster member | 0.0276347 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0263967 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0260736 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0258825 |
| YBX1 | Y box binding protein 1 | 0.0256909 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0255993 |
| SET | SET nuclear proto-oncogene | 0.0254132 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0252916 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.025187 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.024767 |
| RPL19 | ribosomal protein L19 | 0.0244048 |
| HMGB2 | high mobility group box 2 | 0.0233582 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0233502 |
| CKAP5 | cytoskeleton associated protein 5 | 0.023346 |
| USP3 | ubiquitin specific peptidase 3 | 0.0231221 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0229908 |
| TXNRD1 | thioredoxin reductase 1 | 0.0228472 |
| THBS1 | thrombospondin 1 | 0.0228361 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0225157 |
| TPM3 | tropomyosin 3 | 0.022107 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0217542 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0217417 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0215553 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0215351 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0210441 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0209626 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0209306 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0208532 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0207472 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0207043 |
| KIF4A | kinesin family member 4A | 0.0206909 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.020638 |
| CCNL1 | cyclin L1 | 0.020354 |
| MATR3 | matrin 3 | 0.0202161 |
| PDCD5 | programmed cell death 5 | 0.0201515 |
| TPX2 | TPX2, microtubule-associated | 0.0200618 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0199584 |
| RBM25 | RNA binding motif protein 25 | 0.0199513 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0194058 |
| H1-5 | H1.5 linker histone, cluster member | 0.0189971 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0189093 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0188237 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0187968 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0187794 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0187752 |
| QKI | QKI, KH domain containing, RNA binding | 0.018667 |
| PAPOLA | poly(A) polymerase alpha | 0.0179419 |
| CCNA2 | cyclin A2 | 0.0178418 |
| ARHGAP11A | Rho GTPase activating protein 11A | 0.017605 |
| TCP1 | t-complex 1 | 0.0175931 |
| PRR11 | proline rich 11 | 0.0175229 |
| TEX11 | testis expressed 11 | 0.0170814 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0170301 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0169444 |
| ZNF326 | zinc finger protein 326 | 0.0169367 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0169079 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0166809 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0166269 |
| RPS6 | ribosomal protein S6 | 0.0165568 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0164974 |
| RPL12 | ribosomal protein L12 | 0.0164722 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0161448 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | 0.0159472 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.0159158 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0158524 |
| CBX3 | chromobox homolog 3 | 0.0158376 |
| CFL2 | cofilin 2 (muscle) | 0.0157909 |
| FLNA | filamin A, alpha | 0.0157317 |
| RPL3 | ribosomal protein L3 | 0.0157306 |
| NDC80 | NDC80 kinetochore complex component | 0.0157303 |
| PNN | pinin, desmosome associated protein | 0.0157082 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0156908 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0156197 |
| CANX | calnexin | 0.0155776 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0154571 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0152329 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.0152156 |
| CCDC88A | coiled-coil domain containing 88A | 0.0152093 |
| ANXA1 | annexin A1 | 0.0152054 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0151873 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.0151022 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0150738 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0150726 |
| RPS3 | ribosomal protein S3 | 0.0150538 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.195494 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.185517 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.172146 |
| COL11A1 | collagen, type XI, alpha 1 | -0.160447 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.158121 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.155159 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.146043 |
| CADM2 | cell adhesion molecule 2 | -0.133656 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.118298 |
| PCDH9 | protocadherin 9 | -0.0971248 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0927581 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0919543 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0842292 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0829317 |
| PLPP1 | phospholipid phosphatase 1 | -0.0804633 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0793113 |
| COL3A1 | collagen, type III, alpha 1 | -0.0751573 |
| LRRC4C | leucine rich repeat containing 4C | -0.072079 |
| HDAC9 | histone deacetylase 9 | -0.0701348 |
| FNDC3B | fibronectin type III domain containing 3B | -0.068806 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0656696 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0653253 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0633537 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0614144 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.05873 |
| COL5A2 | collagen, type V, alpha 2 | -0.0586142 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0580092 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.057298 |
| PHIP | pleckstrin homology domain interacting protein | -0.0572611 |
| MEIS2 | Meis homeobox 2 | -0.0571099 |
| ANK2 | ankyrin 2, neuronal | -0.0543541 |
| GPC3 | glypican 3 | -0.0541412 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0534048 |
| RBM20 | RNA binding motif protein 20 | -0.0533807 |
| TENM3 | teneurin transmembrane protein 3 | -0.0531411 |
| NEBL | nebulette | -0.0522426 |
| ITGAV | integrin, alpha V | -0.0512697 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0511066 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0507354 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0486807 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0480945 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0478405 |
| NRG1 | neuregulin 1 | -0.0478242 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0473013 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0466094 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0451607 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0450669 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0449279 |
| RAD51B | RAD51 paralog B | -0.0448427 |
| NHSL1 | NHS-like 1 | -0.0443903 |
| FOXP2 | forkhead box P2 | -0.0436649 |
| TOX | thymocyte selection-associated high mobility group box | -0.043437 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0429008 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0421336 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0407308 |
| CDH19 | cadherin 19, type 2 | -0.0403612 |
| SMYD3 | SET and MYND domain containing 3 | -0.039959 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.039636 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0392189 |
| TUT4 | terminal uridylyl transferase 4 | -0.038898 |
| NTM | neurotrimin | -0.0388914 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0387616 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0386606 |
| SNX6 | sorting nexin 6 | -0.0385426 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0385144 |
| JMJD1C | jumonji domain containing 1C | -0.0372252 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0370672 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0370277 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0370242 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0368995 |
| PRKD1 | protein kinase D1 | -0.0367464 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0367358 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0366653 |
| ATXN2 | ataxin 2 | -0.0365336 |
| PRELID2 | PRELI domain containing 2 | -0.0364856 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0363669 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0361799 |
| PGK1 | phosphoglycerate kinase 1 | -0.0350766 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0347022 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0346845 |
| COL1A2 | collagen, type I, alpha 2 | -0.0344823 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0343893 |
| SYT1 | synaptotagmin I | -0.034265 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0342385 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0334869 |
| NFIA | nuclear factor I/A | -0.0329988 |
| USP25 | ubiquitin specific peptidase 25 | -0.0323621 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0323578 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.032344 |
| AHNAK | AHNAK nucleoprotein | -0.0317793 |
| TENM2 | teneurin transmembrane protein 2 | -0.0316559 |
| PHF21A | PHD finger protein 21A | -0.0313723 |
| ANKRD12 | ankyrin repeat domain 12 | -0.03128 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0311346 |
| GSE1 | Gse1 coiled-coil protein | -0.0310424 |
| NXN | nucleoredoxin | -0.0310017 |
| RASAL2 | RAS protein activator like 2 | -0.0309399 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0309285 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0308615 |
| RCOR1 | REST corepressor 1 | -0.0308393 |
