| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Docetaxel (Trihydrate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.0780091 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0767667 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0685341 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0640797 |
| RPLP2 | ribosomal protein, large, P2 | 0.0590666 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0565846 |
| MKI67 | marker of proliferation Ki-67 | 0.0468761 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0458423 |
| CALR | calreticulin | 0.0417122 |
| RPS27A | ribosomal protein S27a | 0.0411987 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0410996 |
| CAVIN1 | caveolae associated protein 1 | 0.0409989 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0395416 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0370358 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.036282 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0332559 |
| AHNAK | AHNAK nucleoprotein | 0.0330024 |
| RPS12 | ribosomal protein S12 | 0.031899 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0309277 |
| TMSB4X | thymosin beta 4, X-linked | 0.0301875 |
| GOLGA4 | golgin A4 | 0.0299882 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0291683 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 0.028977 |
| RPL37A | ribosomal protein L37a | 0.028378 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0275498 |
| RPL26 | ribosomal protein L26 | 0.0273039 |
| RPS3 | ribosomal protein S3 | 0.0268684 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0265125 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0258434 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.0243713 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0234813 |
| RPL38 | ribosomal protein L38 | 0.0232247 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | 0.0229825 |
| PDCD5 | programmed cell death 5 | 0.0229448 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0224537 |
| SET | SET nuclear proto-oncogene | 0.0221238 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0211195 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.019631 |
| RPL12 | ribosomal protein L12 | 0.0185479 |
| CANX | calnexin | 0.0178182 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0176126 |
| RPL4 | ribosomal protein L4 | 0.0174818 |
| EIF3J | eukaryotic translation initiation factor 3, subunit J | 0.0168898 |
| ZNF146 | zinc finger protein 146 | 0.0166488 |
| RPS6 | ribosomal protein S6 | 0.0164997 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0162405 |
| NOL7 | nucleolar protein 7, 27kDa | 0.01586 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0154709 |
| RPL5 | ribosomal protein L5 | 0.0153492 |
| RPL21 | ribosomal protein L21 | 0.0153021 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0150387 |
| CENPE | centromere protein E, 312kDa | 0.0148235 |
| RPS15A | ribosomal protein S15a | 0.0148049 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.014791 |
| RPL36A | ribosomal protein L36a | 0.0147206 |
| RPS8 | ribosomal protein S8 | 0.0141582 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0141163 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0140424 |
| KIF5B | kinesin family member 5B | 0.0138508 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0137934 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0136913 |
| RPL13A | ribosomal protein L13a | 0.0136679 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0136635 |
| UBC | ubiquitin C | 0.0134101 |
| SSU72 | SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) | 0.0133684 |
| LMNA | lamin A/C | 0.0133058 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0132608 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0129257 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.0129055 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0126808 |
| BCCIP | BRCA2 and CDKN1A interacting protein | 0.0126516 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0125046 |
| PSMA4 | proteasome (prosome, macropain) subunit, alpha type, 4 | 0.0124361 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0124061 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0123984 |
| FLNA | filamin A, alpha | 0.0123626 |
| RBM25 | RNA binding motif protein 25 | 0.0123308 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0123304 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 0.0123161 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0122259 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0121306 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0120457 |
| RPL19 | ribosomal protein L19 | 0.0120231 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0118558 |
| CBX3 | chromobox homolog 3 | 0.011749 |
| SAFB | scaffold attachment factor B | 0.0116794 |
| RPS17 | ribosomal protein S17 | 0.0116722 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0116656 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0115933 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0115867 |
| HMGB2 | high mobility group box 2 | 0.0115377 |
| FUS | FUS RNA binding protein | 0.0114994 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0114215 |
| RAB13 | RAB13, member RAS oncogene family | 0.0113366 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0111589 |
| CCAR1 | cell division cycle and apoptosis regulator 1 | 0.0110957 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | 0.011068 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0110629 |
| SERINC1 | serine incorporator 1 | 0.0110479 |
| SAFB2 | scaffold attachment factor B2 | 0.0110267 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.205895 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.174411 |
| VCL | vinculin | -0.171034 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.155003 |
| FNDC3B | fibronectin type III domain containing 3B | -0.148944 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.114214 |
| VIM | vimentin | -0.102665 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0978228 |
| ACTN4 | actinin, alpha 4 | -0.0908906 |
| RPS16 | ribosomal protein S16 | -0.0862707 |
| JMJD1C | jumonji domain containing 1C | -0.0854838 |
| ZFP36 | ZFP36 ring finger protein | -0.0847566 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0736372 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0715383 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | -0.0687165 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0676811 |
| EGR1 | early growth response 1 | -0.0669177 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0665026 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0640713 |
| RTN4 | reticulon 4 | -0.0636264 |
| LDHA | lactate dehydrogenase A | -0.0612833 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | -0.0601971 |
| SEPTIN9 | septin 9 | -0.0598047 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0595501 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0592476 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0581812 |
| VMP1 | vacuole membrane protein 1 | -0.0574702 |
| FOSL1 | FOS-like antigen 1 | -0.0568839 |
| MT2A | metallothionein 2A | -0.0565076 |
| PTK2 | protein tyrosine kinase 2 | -0.0554962 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.055141 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0538817 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0533242 |
| HMGA1 | high mobility group AT-hook 1 | -0.0530247 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0525499 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0512951 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0511177 |
| EGFR | epidermal growth factor receptor | -0.0509907 |
| SBF2 | SET binding factor 2 | -0.0507982 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0503291 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0495151 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0492625 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0479638 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0477605 |
| MCL1 | myeloid cell leukemia 1 | -0.0477424 |
| PDE10A | phosphodiesterase 10A | -0.0473636 |
| FTL | ferritin, light polypeptide | -0.047281 |
| POTEF | POTE ankyrin domain family, member F | -0.0468628 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0466324 |
| TMSB10 | thymosin beta 10 | -0.046583 |
| RPL35A | ribosomal protein L35a | -0.0463646 |
| ATXN1 | ataxin 1 | -0.0462911 |
| CD44 | CD44 molecule (Indian blood group) | -0.0462004 |
| MYOF | myoferlin | -0.0460841 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0449414 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0442829 |
| DST | dystonin | -0.044106 |
| SMAD3 | SMAD family member 3 | -0.0439098 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.043458 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0422817 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0420122 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0420091 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.041384 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0398193 |
| TPM1 | tropomyosin 1 (alpha) | -0.0395098 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0385338 |
| PKM | pyruvate kinase, muscle | -0.0384543 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0375992 |
| FBL | fibrillarin | -0.0372991 |
| ITGAV | integrin, alpha V | -0.0372396 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0371659 |
| ATP13A3 | ATPase type 13A3 | -0.0370021 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0366121 |
| MAP1B | microtubule-associated protein 1B | -0.0365253 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.036212 |
| FMNL2 | formin-like 2 | -0.0359737 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0357465 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0356316 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0355382 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0352633 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0349178 |
| NAV2 | neuron navigator 2 | -0.0346957 |
| CTSD | cathepsin D | -0.0346658 |
| MYO10 | myosin X | -0.0345932 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0339811 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0338751 |
| RNF220 | ring finger protein 220 | -0.0336965 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0328726 |
| IPO7 | importin 7 | -0.032755 |
| PFN1 | profilin 1 | -0.0325528 |
| MEF2A | myocyte enhancer factor 2A | -0.0323453 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0320453 |
| NHSL1 | NHS-like 1 | -0.032002 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0319984 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0317031 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0314633 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0310704 |
| CDK19 | cyclin-dependent kinase 19 | -0.0309696 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0308346 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0308076 |
