| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.156215 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.114215 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0713067 |
| TMSB4X | thymosin beta 4, X-linked | 0.0644732 |
| CALR | calreticulin | 0.0624143 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0610511 |
| RPS6 | ribosomal protein S6 | 0.0576791 |
| RPS12 | ribosomal protein S12 | 0.0503484 |
| G0S2 | G0/G1 switch 2 | 0.0499884 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0494006 |
| RPS27A | ribosomal protein S27a | 0.0493269 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0489077 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0483067 |
| RPS3 | ribosomal protein S3 | 0.0468056 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0460075 |
| HDGF | hepatoma-derived growth factor | 0.0447504 |
| RPL37A | ribosomal protein L37a | 0.0440438 |
| OGA | O-GlcNAcase | 0.043623 |
| GOLGA4 | golgin A4 | 0.0429804 |
| SET | SET nuclear proto-oncogene | 0.0424576 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0421641 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0378715 |
| MKI67 | marker of proliferation Ki-67 | 0.03772 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0365941 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0360675 |
| MTAP | methylthioadenosine phosphorylase | 0.0346814 |
| XPO1 | exportin 1 | 0.0340699 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0330711 |
| FMNL2 | formin-like 2 | 0.0321985 |
| CENPF | centromere protein F, 350/400kDa | 0.0315445 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0314601 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0305868 |
| TPM3 | tropomyosin 3 | 0.0293919 |
| RBM25 | RNA binding motif protein 25 | 0.0291985 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0291306 |
| VIM | vimentin | 0.0288113 |
| SQSTM1 | sequestosome 1 | 0.0287294 |
| RPS8 | ribosomal protein S8 | 0.0286546 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0283784 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0281959 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0278622 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0276409 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.027279 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0272387 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.026776 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | 0.0267112 |
| FLNA | filamin A, alpha | 0.0265322 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0259999 |
| KIF5B | kinesin family member 5B | 0.0259823 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0250575 |
| RPL21 | ribosomal protein L21 | 0.0250221 |
| SRPK1 | SRSF protein kinase 1 | 0.0247105 |
| UBC | ubiquitin C | 0.0246555 |
| ANLN | anillin, actin binding protein | 0.0235982 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0233441 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0233119 |
| RPS17 | ribosomal protein S17 | 0.0230966 |
| SLTM | SAFB-like, transcription modulator | 0.0229941 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0227438 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0226917 |
| TPM4 | tropomyosin 4 | 0.0226738 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0226454 |
| SPAG9 | sperm associated antigen 9 | 0.0226175 |
| RPLP2 | ribosomal protein, large, P2 | 0.0222759 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.022015 |
| DSTN | destrin (actin depolymerizing factor) | 0.0219893 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0217976 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0215986 |
| SP100 | SP100 nuclear antigen | 0.0214277 |
| SLMAP | sarcolemma associated protein | 0.0213648 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0211202 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0210655 |
| RPL12 | ribosomal protein L12 | 0.020896 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0207912 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0207292 |
| PLAT | plasminogen activator, tissue | 0.0206521 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0205177 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0205122 |
| CAB39 | calcium binding protein 39 | 0.0204747 |
| FOSL1 | FOS-like antigen 1 | 0.0204096 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0203208 |
| PDE8A | phosphodiesterase 8A | 0.0201916 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0201336 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0199692 |
| SRP54 | signal recognition particle 54kDa | 0.019913 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.0197325 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0195759 |
| PDS5B | PDS5 cohesin associated factor B | 0.0195374 |
| CTTN | cortactin | 0.0194798 |
| NCKAP1 | NCK-associated protein 1 | 0.0194307 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0193126 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0193094 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0193067 |
| RAI1 | retinoic acid induced 1 | 0.019293 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0190775 |
| ADM | adrenomedullin | 0.0190011 |
| FAM13A | family with sequence similarity 13, member A | 0.0187314 |
| RPN1 | ribophorin I | 0.0186424 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0185067 |
| DTNA | dystrobrevin, alpha | 0.0183822 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.302067 |
| MT2A | metallothionein 2A | -0.121925 |
| LDHA | lactate dehydrogenase A | -0.109993 |
| HMGA1 | high mobility group AT-hook 1 | -0.105964 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0991838 |
| B2M | beta-2-microglobulin | -0.095354 |
| EGR1 | early growth response 1 | -0.0942625 |
| EMP1 | epithelial membrane protein 1 | -0.093194 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0878715 |
| LMO7 | LIM domain 7 | -0.0868147 |
| TGM2 | transglutaminase 2 | -0.0849224 |
| RPL35A | ribosomal protein L35a | -0.0838231 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0823812 |
| LAMA4 | laminin, alpha 4 | -0.0795572 |
| KRT19 | keratin 19, type I | -0.073179 |
| RASAL2 | RAS protein activator like 2 | -0.0730572 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0718222 |
| MYO1E | myosin IE | -0.0692861 |
| POTEF | POTE ankyrin domain family, member F | -0.0676457 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0671354 |
| ANXA2 | annexin A2 | -0.0665349 |
| WWC1 | WW and C2 domain containing 1 | -0.0663971 |
| VMP1 | vacuole membrane protein 1 | -0.0643819 |
| TJP1 | tight junction protein 1 | -0.0627972 |
| MYOF | myoferlin | -0.0622053 |
| VCL | vinculin | -0.0621095 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0612832 |
| OSMR | oncostatin M receptor | -0.0611585 |
| NDRG1 | N-myc downstream regulated 1 | -0.0598138 |
| INTS6 | integrator complex subunit 6 | -0.0590982 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0589003 |
| PLSCR1 | phospholipid scramblase 1 | -0.0576818 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0565233 |
| ACTN4 | actinin, alpha 4 | -0.0560787 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0553191 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0545384 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0539592 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0528728 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0520321 |
| RPLP1 | ribosomal protein, large, P1 | -0.0517133 |
| FAM3C | family with sequence similarity 3, member C | -0.0513723 |
| ERBIN | erbb2 interacting protein | -0.0503193 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0497027 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0496205 |
| AHNAK | AHNAK nucleoprotein | -0.0495812 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0491939 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0483268 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.048153 |
| EZR | ezrin | -0.0481449 |
| LAMB3 | laminin, beta 3 | -0.0470324 |
| MUC4 | mucin 4, cell surface associated | -0.0466415 |
| LATS2 | large tumor suppressor kinase 2 | -0.0457638 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0454993 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0441958 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0423673 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0418991 |
| SMAD3 | SMAD family member 3 | -0.04103 |
| SMYD3 | SET and MYND domain containing 3 | -0.0401768 |
| DIAPH1 | diaphanous-related formin 1 | -0.0394994 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0391347 |
| ACTG1 | actin gamma 1 | -0.039084 |
| ETV6 | ets variant 6 | -0.0390099 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0389945 |
| BCL2L1 | BCL2-like 1 | -0.0384352 |
| PGK1 | phosphoglycerate kinase 1 | -0.0379123 |
| RPS13 | ribosomal protein S13 | -0.0376592 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0376535 |
| EFNA5 | ephrin-A5 | -0.0374187 |
| EGFR | epidermal growth factor receptor | -0.0363653 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0363289 |
| AREG | amphiregulin | -0.0356914 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.035488 |
| TXNIP | thioredoxin interacting protein | -0.0349911 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0347211 |
| DSG2 | desmoglein 2 | -0.034698 |
| SEPTIN9 | septin 9 | -0.0345612 |
| TAPBP | TAP binding protein (tapasin) | -0.0344377 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0343409 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0338784 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0335677 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0334699 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0331362 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0329607 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0326341 |
| FAM107B | family with sequence similarity 107, member B | -0.0323576 |
| TGFA | transforming growth factor, alpha | -0.0321203 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0320313 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0318962 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0316746 |
| PLPP6 | phospholipid phosphatase 6 | -0.0315625 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0314318 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0311835 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0309326 |
| ZNF644 | zinc finger protein 644 | -0.0308117 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0307151 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0304522 |
| SDC4 | syndecan 4 | -0.0303905 |
| RCOR1 | REST corepressor 1 | -0.0300328 |
| HLA-E | major histocompatibility complex, class I, E | -0.0299217 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0299179 |
