| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUP58 | nucleoporin 58 | 0.0262543 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0208059 |
| ZNF292 | zinc finger protein 292 | 0.0202423 |
| NCKAP1 | NCK-associated protein 1 | 0.0200536 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0182149 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0178492 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0157515 |
| SPAG9 | sperm associated antigen 9 | 0.0152228 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0151392 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.014402 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0143976 |
| RPL3 | ribosomal protein L3 | 0.0143907 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.014182 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0139713 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0136453 |
| KIF5B | kinesin family member 5B | 0.013618 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0134802 |
| CCNL1 | cyclin L1 | 0.0131172 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0130346 |
| RLF | rearranged L-myc fusion | 0.0129952 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0128657 |
| TPX2 | TPX2, microtubule-associated | 0.0127811 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0127435 |
| NEK7 | NIMA-related kinase 7 | 0.0126116 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0124924 |
| OGA | O-GlcNAcase | 0.0124731 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0123721 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0123379 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0123214 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0119854 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0119569 |
| RBM33 | RNA binding motif protein 33 | 0.0118212 |
| HELZ | helicase with zinc finger | 0.011802 |
| UBXN7 | UBX domain protein 7 | 0.0116198 |
| HDAC3 | histone deacetylase 3 | 0.0116024 |
| FOXJ3 | forkhead box J3 | 0.0115007 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0114865 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0113709 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.011266 |
| YTHDC1 | YTH domain containing 1 | 0.0112136 |
| POU2F1 | POU class 2 homeobox 1 | 0.0111715 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0110126 |
| ZNF654 | zinc finger protein 654 | 0.0110071 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.010907 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.010858 |
| SUCO | SUN domain containing ossification factor | 0.0107095 |
| RNF145 | ring finger protein 145 | 0.0106722 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0106379 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0106237 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0104577 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0103917 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0101251 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.0101055 |
| NUP54 | nucleoporin 54kDa | 0.00996996 |
| YME1L1 | YME1-like 1 ATPase | 0.00991639 |
| RAB18 | RAB18, member RAS oncogene family | 0.00988083 |
| FAR1 | fatty acyl CoA reductase 1 | 0.00979652 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.00977131 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.00969711 |
| PHIP | pleckstrin homology domain interacting protein | 0.00949772 |
| USP3 | ubiquitin specific peptidase 3 | 0.00943956 |
| CASC3 | cancer susceptibility candidate 3 | 0.00943104 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.00939296 |
| RIOK3 | RIO kinase 3 | 0.00932223 |
| NAA35 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit | 0.00932126 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0092744 |
| MEF2A | myocyte enhancer factor 2A | 0.00927226 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.00921826 |
| FOXO3 | forkhead box O3 | 0.00912511 |
| PCBP2 | poly(rC) binding protein 2 | 0.00911987 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.00905305 |
| RYBP | RING1 and YY1 binding protein | 0.00905153 |
| ATP11B | ATPase, class VI, type 11B | 0.00903386 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.00897952 |
| TFG | TRK-fused gene | 0.00893093 |
| ANLN | anillin, actin binding protein | 0.00888707 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0088282 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.00879228 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.00874595 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.00869773 |
| ABI1 | abl-interactor 1 | 0.00866228 |
| IFRD1 | interferon-related developmental regulator 1 | 0.00853547 |
| ARHGAP11A | Rho GTPase activating protein 11A | 0.00853152 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00839699 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00830539 |
| MTF2 | metal response element binding transcription factor 2 | 0.00828253 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.00821939 |
| ATP13A3 | ATPase type 13A3 | 0.0081939 |
| CKAP5 | cytoskeleton associated protein 5 | 0.00818283 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.00812747 |
| PUM2 | pumilio RNA-binding family member 2 | 0.00804877 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00803092 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.00797867 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.00796919 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.00795482 |
| MXD1 | MAX dimerization protein 1 | 0.00787545 |
| MTMR3 | myotubularin related protein 3 | 0.007861 |
| ZNF451 | zinc finger protein 451 | 0.00783595 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.00780831 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.00779698 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DLC1 | DLC1 Rho GTPase activating protein | -0.172707 |
| MT2A | metallothionein 2A | -0.147577 |
| NAV3 | neuron navigator 3 | -0.125075 |
| ZNF438 | zinc finger protein 438 | -0.120586 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.118034 |
| FRMD4A | FERM domain containing 4A | -0.11102 |
| FLNB | filamin B, beta | -0.10542 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.101578 |
| FRMD6 | FERM domain containing 6 | -0.0818294 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0788114 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0728848 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0720817 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0715157 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.062256 |
| RPS6 | ribosomal protein S6 | -0.061267 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0607686 |
| HMGA2 | high mobility group AT-hook 2 | -0.0602055 |
| LAMB3 | laminin, beta 3 | -0.0601786 |
| ACTG1 | actin gamma 1 | -0.0596035 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0582941 |
| BNC2 | basonuclin 2 | -0.0570506 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0548219 |
| HDAC9 | histone deacetylase 9 | -0.0540013 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0535431 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0497578 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0485524 |
| RPL35A | ribosomal protein L35a | -0.0472443 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0469003 |
| FTL | ferritin, light polypeptide | -0.0466856 |
| NAV2 | neuron navigator 2 | -0.0461053 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0458938 |
| TPM4 | tropomyosin 4 | -0.0457217 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.044941 |
| RPS8 | ribosomal protein S8 | -0.0448975 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0440625 |
| RPLP1 | ribosomal protein, large, P1 | -0.0431007 |
| DGKI | diacylglycerol kinase, iota | -0.0414722 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.041336 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0410592 |
| STC1 | stanniocalcin 1 | -0.040997 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0405186 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0403299 |
| TTR | transthyretin | -0.0394247 |
| RPL12 | ribosomal protein L12 | -0.0392226 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0390893 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0388114 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0387104 |
| RPL7A | ribosomal protein L7a | -0.0386601 |
| NABP1 | nucleic acid binding protein 1 | -0.0380488 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0374228 |
| HMGA1 | high mobility group AT-hook 1 | -0.0373953 |
| TMSB10 | thymosin beta 10 | -0.0372613 |
| RAD51B | RAD51 paralog B | -0.0372497 |
| RPL8 | ribosomal protein L8 | -0.0372009 |
| EFNB2 | ephrin-B2 | -0.0362504 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0343048 |
| RPS3 | ribosomal protein S3 | -0.0340009 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0339049 |
| RPLP0 | ribosomal protein, large, P0 | -0.0334915 |
| ASPH | aspartate beta-hydroxylase | -0.0331844 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0322633 |
| CALD1 | caldesmon 1 | -0.0320442 |
| RPL37A | ribosomal protein L37a | -0.0319688 |
| FHIT | fragile histidine triad | -0.0318256 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0314455 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0314048 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0303248 |
| MTAP | methylthioadenosine phosphorylase | -0.030212 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0301671 |
| LDHA | lactate dehydrogenase A | -0.0298797 |
| RPS19 | ribosomal protein S19 | -0.0298177 |
| RPL26 | ribosomal protein L26 | -0.0298165 |
| SMYD3 | SET and MYND domain containing 3 | -0.0297727 |
| RPL30 | ribosomal protein L30 | -0.0297578 |
| SP100 | SP100 nuclear antigen | -0.0296164 |
| ENO1 | enolase 1, (alpha) | -0.0293248 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0292145 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0290918 |
| RPL9 | ribosomal protein L9 | -0.0289614 |
| RPL7 | ribosomal protein L7 | -0.028537 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0279022 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.027616 |
| PGK1 | phosphoglycerate kinase 1 | -0.0275479 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0274066 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0273985 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0273742 |
| RPS12 | ribosomal protein S12 | -0.0272743 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0267892 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0263132 |
| RRBP1 | ribosome binding protein 1 | -0.0262682 |
| JMJD1C | jumonji domain containing 1C | -0.0262491 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0261855 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0260875 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0260663 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0260151 |
| RPS29 | ribosomal protein S29 | -0.025449 |
| RPS24 | ribosomal protein S24 | -0.0253493 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0251726 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0250064 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0249635 |
