| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.0937084 |
| PTMA | prothymosin, alpha | 0.0908751 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0887609 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0782413 |
| MKI67 | marker of proliferation Ki-67 | 0.0699371 |
| MT2A | metallothionein 2A | 0.0656156 |
| CENPF | centromere protein F, 350/400kDa | 0.0647216 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.059367 |
| RPS6 | ribosomal protein S6 | 0.0585835 |
| CALR | calreticulin | 0.0551319 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0535274 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0493736 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0479032 |
| RPLP2 | ribosomal protein, large, P2 | 0.0454235 |
| RPS12 | ribosomal protein S12 | 0.0454109 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0448245 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0445139 |
| STC1 | stanniocalcin 1 | 0.0425259 |
| RPL37A | ribosomal protein L37a | 0.0408561 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0402477 |
| RPS17 | ribosomal protein S17 | 0.0401979 |
| RPS19 | ribosomal protein S19 | 0.0398417 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0393664 |
| TPX2 | TPX2, microtubule-associated | 0.0391813 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0391602 |
| ADM | adrenomedullin | 0.0383741 |
| RPS3 | ribosomal protein S3 | 0.0377754 |
| ZNF292 | zinc finger protein 292 | 0.0373852 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.035867 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0353214 |
| RPL11 | ribosomal protein L11 | 0.0349419 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0349362 |
| RPL12 | ribosomal protein L12 | 0.0348429 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0345661 |
| RPS27A | ribosomal protein S27a | 0.0337501 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0329595 |
| HDGF | hepatoma-derived growth factor | 0.0322126 |
| GOLGA4 | golgin A4 | 0.031576 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0312212 |
| CBX3 | chromobox homolog 3 | 0.0308924 |
| XPO1 | exportin 1 | 0.0307022 |
| FAM13A | family with sequence similarity 13, member A | 0.030301 |
| ANLN | anillin, actin binding protein | 0.0302734 |
| TUBA1B | tubulin, alpha 1b | 0.0301604 |
| KIF5B | kinesin family member 5B | 0.029595 |
| RPS8 | ribosomal protein S8 | 0.0294772 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0293831 |
| RPL5 | ribosomal protein L5 | 0.0292578 |
| RPL23 | ribosomal protein L23 | 0.0288809 |
| TMSB10 | thymosin beta 10 | 0.0285796 |
| FAM162A | family with sequence similarity 162, member A | 0.0285152 |
| SET | SET nuclear proto-oncogene | 0.028478 |
| YBX1 | Y box binding protein 1 | 0.0280835 |
| RPL32 | ribosomal protein L32 | 0.0265746 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.026449 |
| RPL13A | ribosomal protein L13a | 0.0263039 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0259234 |
| RPL36 | ribosomal protein L36 | 0.0258338 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0255548 |
| RPL26 | ribosomal protein L26 | 0.0251779 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0251775 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0249715 |
| RPLP1 | ribosomal protein, large, P1 | 0.024954 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0248799 |
| RPS25 | ribosomal protein S25 | 0.0245674 |
| UBC | ubiquitin C | 0.0241386 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0241106 |
| VEGFA | vascular endothelial growth factor A | 0.0240856 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0240756 |
| NUP58 | nucleoporin 58 | 0.0240636 |
| RPL19 | ribosomal protein L19 | 0.0239729 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0239183 |
| PCBP2 | poly(rC) binding protein 2 | 0.0238121 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0233821 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0232927 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0232889 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0230588 |
| ENO1 | enolase 1, (alpha) | 0.0229051 |
| CKAP2L | cytoskeleton associated protein 2-like | 0.0228037 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0227011 |
| ARHGAP11A | Rho GTPase activating protein 11A | 0.0226688 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0226111 |
| PRC1 | protein regulator of cytokinesis 1 | 0.0224251 |
| TPM3 | tropomyosin 3 | 0.022221 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0219347 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0216763 |
| H1-0 | H1.0 linker histone | 0.0216321 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0212295 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0208795 |
| SERF2 | small EDRK-rich factor 2 | 0.0208659 |
| CCNL1 | cyclin L1 | 0.0207524 |
| CENPE | centromere protein E, 312kDa | 0.0207247 |
| RPL7A | ribosomal protein L7a | 0.0207218 |
| CANX | calnexin | 0.0207043 |
| FTL | ferritin, light polypeptide | 0.0206561 |
| RPS11 | ribosomal protein S11 | 0.0204861 |
| RPS16 | ribosomal protein S16 | 0.0203658 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.020241 |
| PDCD5 | programmed cell death 5 | 0.0200073 |
| LMNA | lamin A/C | 0.0199639 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.306163 |
| FRMD4A | FERM domain containing 4A | -0.143997 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.139419 |
| CD44 | CD44 molecule (Indian blood group) | -0.102216 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0926228 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0912377 |
| TMEM178B | transmembrane protein 178B | -0.0725105 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0720397 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0707421 |
| VCL | vinculin | -0.0670552 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0662368 |
| FAM20C | family with sequence similarity 20, member C | -0.0656659 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0610319 |
| NAV1 | neuron navigator 1 | -0.0609064 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0593958 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0588128 |
| HPCAL1 | hippocalcin-like 1 | -0.0581373 |
| COL5A1 | collagen, type V, alpha 1 | -0.0571389 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0558717 |
| SVIL | supervillin | -0.0555255 |
| NRP1 | neuropilin 1 | -0.0554375 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0553337 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0537991 |
| HLA-B | major histocompatibility complex, class I, B | -0.0519571 |
| PCBP3 | poly(rC) binding protein 3 | -0.0513083 |
| COL1A1 | collagen, type I, alpha 1 | -0.049882 |
| GLIS3 | GLIS family zinc finger 3 | -0.0496546 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0494387 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.048963 |
| LOXL2 | lysyl oxidase-like 2 | -0.0474639 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0471149 |
| COL5A3 | collagen, type V, alpha 3 | -0.0463046 |
| ANXA2 | annexin A2 | -0.0449538 |
| SMAD3 | SMAD family member 3 | -0.0448297 |
| TNNC1 | troponin C type 1 (slow) | -0.0445042 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0440845 |
| B2M | beta-2-microglobulin | -0.0432558 |
| LDHA | lactate dehydrogenase A | -0.0432541 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0422853 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0414809 |
| ASPH | aspartate beta-hydroxylase | -0.0412053 |
| EGR1 | early growth response 1 | -0.0410658 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0407438 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0394299 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.038321 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0367584 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0362771 |
| ANKRD28 | ankyrin repeat domain 28 | -0.036222 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0358124 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0355658 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0354211 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0353546 |
| NDRG1 | N-myc downstream regulated 1 | -0.0352515 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0349036 |
| TNS3 | tensin 3 | -0.0348936 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0345001 |
| TPM1 | tropomyosin 1 (alpha) | -0.0341449 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0340494 |
| NF1 | neurofibromin 1 | -0.0340312 |
| MEF2A | myocyte enhancer factor 2A | -0.0340079 |
| FBXO11 | F-box protein 11 | -0.0336181 |
| CDH13 | cadherin 13 | -0.0335443 |
| FHIT | fragile histidine triad | -0.0328303 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0325295 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0322181 |
| HMGA2 | high mobility group AT-hook 2 | -0.032198 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0321329 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0317393 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0311792 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0311785 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0309892 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0309597 |
| ATXN1 | ataxin 1 | -0.0308609 |
| ZNF644 | zinc finger protein 644 | -0.0308284 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0302358 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0300469 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0299102 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0298156 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0297341 |
| ACTN1 | actinin, alpha 1 | -0.0295331 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0291319 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0288499 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0287463 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0284753 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0279976 |
| CDK13 | cyclin-dependent kinase 13 | -0.0279959 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0274997 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0273588 |
| INTS6 | integrator complex subunit 6 | -0.0273283 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0271993 |
| SHISA5 | shisa family member 5 | -0.0271755 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0267609 |
| MYO1E | myosin IE | -0.0264676 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0264545 |
| MX2 | MX dynamin-like GTPase 2 | -0.0261633 |
| MTSS1 | metastasis suppressor 1 | -0.0260889 |
| TSPAN9 | tetraspanin 9 | -0.025859 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0254286 |
| CLIC4 | chloride intracellular channel 4 | -0.0252584 |
| AOPEP | aminopeptidase O (putative) | -0.0251068 |
