| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Docetaxel (Trihydrate)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS12 | ribosomal protein S12 | 0.0512338 |
| RPS3 | ribosomal protein S3 | 0.0469049 |
| FTL | ferritin, light polypeptide | 0.0465312 |
| RPS6 | ribosomal protein S6 | 0.0439373 |
| RPLP2 | ribosomal protein, large, P2 | 0.0406433 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0403542 |
| FN1 | fibronectin 1 | 0.0380542 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0346773 |
| RPL37A | ribosomal protein L37a | 0.0336723 |
| RPL38 | ribosomal protein L38 | 0.0331642 |
| RPL32 | ribosomal protein L32 | 0.0293138 |
| RPL12 | ribosomal protein L12 | 0.0281428 |
| RPS17 | ribosomal protein S17 | 0.0262545 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.025593 |
| RPL11 | ribosomal protein L11 | 0.0255221 |
| RPL7A | ribosomal protein L7a | 0.0199408 |
| RPL27 | ribosomal protein L27 | 0.0186052 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0182939 |
| RPL5 | ribosomal protein L5 | 0.0179935 |
| MKI67 | marker of proliferation Ki-67 | 0.0178894 |
| RPL35 | ribosomal protein L35 | 0.0175353 |
| RPS27 | ribosomal protein S27 | 0.0174333 |
| RPS14 | ribosomal protein S14 | 0.017234 |
| RPL37 | ribosomal protein L37 | 0.0172279 |
| RPL31 | ribosomal protein L31 | 0.016992 |
| RPS2 | ribosomal protein S2 | 0.0168091 |
| RAB13 | RAB13, member RAS oncogene family | 0.0163403 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0163273 |
| RPL13A | ribosomal protein L13a | 0.0160155 |
| RPS25 | ribosomal protein S25 | 0.0158091 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0148546 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0147241 |
| RPS19 | ribosomal protein S19 | 0.0143342 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.014026 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0138164 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.013813 |
| RPL36 | ribosomal protein L36 | 0.0136048 |
| RPS10 | ribosomal protein S10 | 0.0135943 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0132862 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0131088 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0130546 |
| S100A9 | S100 calcium binding protein A9 | 0.0128576 |
| RPS8 | ribosomal protein S8 | 0.0128481 |
| FAM13A | family with sequence similarity 13, member A | 0.0123592 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.0122669 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 0.0122444 |
| TENM1 | teneurin transmembrane protein 1 | 0.0121841 |
| RPS23 | ribosomal protein S23 | 0.0117451 |
| DCAF5 | DDB1 and CUL4 associated factor 5 | 0.0117396 |
| RPL35A | ribosomal protein L35a | 0.0117102 |
| HDGF | hepatoma-derived growth factor | 0.0116323 |
| RPS16 | ribosomal protein S16 | 0.0115586 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0115002 |
| EEA1 | early endosome antigen 1 | 0.0114878 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0114594 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | 0.0113519 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0113125 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0112311 |
| RPL19 | ribosomal protein L19 | 0.011166 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0111296 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | 0.0109726 |
| RACK1 | receptor for activated C kinase 1 | 0.0108553 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0106799 |
| PPP1R3B | protein phosphatase 1, regulatory subunit 3B | 0.0106177 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0105589 |
| RPL26 | ribosomal protein L26 | 0.0104138 |
| CAPRIN1 | cell cycle associated protein 1 | 0.010077 |
| RPS15 | ribosomal protein S15 | 0.00990096 |
| FAM117B | family with sequence similarity 117, member B | 0.00986443 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | 0.00980412 |
| UBXN7 | UBX domain protein 7 | 0.00976532 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00961066 |
| PRELID1 | PRELI domain containing 1 | 0.0096008 |
| PDAP1 | PDGFA associated protein 1 | 0.00941646 |
| SERF2 | small EDRK-rich factor 2 | 0.00937789 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | 0.00937677 |
| UPP1 | uridine phosphorylase 1 | 0.00930182 |
| RPS24 | ribosomal protein S24 | 0.00925341 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.00924601 |
| KAZN | kazrin, periplakin interacting protein | 0.00907815 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.009047 |
| RPL27A | ribosomal protein L27a | 0.00900129 |
| NOL7 | nucleolar protein 7, 27kDa | 0.00892241 |
| MLEC | malectin | 0.00882998 |
| FAM162A | family with sequence similarity 162, member A | 0.00882364 |
| NIFK | nucleolar protein interacting with the FHA domain of MKI67 | 0.00860592 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00854785 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0084047 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00838184 |
| RPL34 | ribosomal protein L34 | 0.00836019 |
| RSL24D1 | ribosomal L24 domain containing 1 | 0.00832428 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | 0.00823159 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.00814792 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 0.00806243 |
| RPLP0 | ribosomal protein, large, P0 | 0.00805675 |
| PRC1 | protein regulator of cytokinesis 1 | 0.008049 |
| H2AZ1 | H2A.Z variant histone 1 | 0.00798422 |
| RPS11 | ribosomal protein S11 | 0.0078945 |
| TMEM45A | transmembrane protein 45A | 0.00788679 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0078057 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.185939 |
| UBC | ubiquitin C | -0.100018 |
| FMN1 | formin 1 | -0.0902815 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0838607 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0835616 |
| ENO1 | enolase 1, (alpha) | -0.0768969 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0723244 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0717898 |
| NRG3 | neuregulin 3 | -0.0681538 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.063434 |
| POTEF | POTE ankyrin domain family, member F | -0.0586201 |
| LDHA | lactate dehydrogenase A | -0.0585455 |
| NLGN1 | neuroligin 1 | -0.0578512 |
| PGK1 | phosphoglycerate kinase 1 | -0.0556857 |
| PKM | pyruvate kinase, muscle | -0.0532556 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0523984 |
| PCBP2 | poly(rC) binding protein 2 | -0.0497579 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0489827 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0478221 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0474937 |
| MT2A | metallothionein 2A | -0.0459269 |
| NAV2 | neuron navigator 2 | -0.0450634 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0424225 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0417918 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0416792 |
| CCND1 | cyclin D1 | -0.0411611 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0404344 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0401865 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.039992 |
| B2M | beta-2-microglobulin | -0.0398394 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0396739 |
| EMP1 | epithelial membrane protein 1 | -0.0386246 |
| TXNRD1 | thioredoxin reductase 1 | -0.0384951 |
| NOTCH2 | notch 2 | -0.0372883 |
| SQSTM1 | sequestosome 1 | -0.0370264 |
| ACTN4 | actinin, alpha 4 | -0.0360114 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0346582 |
| ANXA2 | annexin A2 | -0.0343265 |
| RUNX1 | runt-related transcription factor 1 | -0.0342464 |
| ATXN1 | ataxin 1 | -0.0340294 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0339397 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0338881 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0332273 |
| RAD51B | RAD51 paralog B | -0.0322241 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0319949 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0318361 |
| EP300 | E1A binding protein p300 | -0.0315986 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0313742 |
| AHNAK | AHNAK nucleoprotein | -0.0312972 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0311859 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0311605 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0304208 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0299949 |
| MAP4 | microtubule-associated protein 4 | -0.0299636 |
| CD44 | CD44 molecule (Indian blood group) | -0.0296719 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0296601 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0289497 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0283708 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0281853 |
| RASAL2 | RAS protein activator like 2 | -0.0280355 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0277179 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0270093 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0269492 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0269407 |
| RHOA | ras homolog family member A | -0.0267413 |
| MSN | moesin | -0.026737 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0266902 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0266511 |
| FRMD4A | FERM domain containing 4A | -0.0266161 |
| CANX | calnexin | -0.026563 |
| VMP1 | vacuole membrane protein 1 | -0.0265025 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.026433 |
| TPM3 | tropomyosin 3 | -0.0263846 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0263483 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0261988 |
| DIAPH1 | diaphanous-related formin 1 | -0.0260522 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0259099 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0258969 |
| SEPTIN7 | septin 7 | -0.0258088 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0255224 |
| CLIC4 | chloride intracellular channel 4 | -0.0253947 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0253503 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0253432 |
| PTK2 | protein tyrosine kinase 2 | -0.0250226 |
| PMEL | premelanosome protein | -0.0249199 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0249077 |
| RTN4 | reticulon 4 | -0.0245985 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0244037 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0241328 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0241182 |
| FRMD5 | FERM domain containing 5 | -0.0240234 |
| FAM13B | family with sequence similarity 13, member B | -0.0238732 |
| HLA-E | major histocompatibility complex, class I, E | -0.0238615 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0237147 |
| SMYD3 | SET and MYND domain containing 3 | -0.0237069 |
| CTTN | cortactin | -0.0236409 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0233691 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0233662 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0233407 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0232913 |
