| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0685745 |
| RPL3 | ribosomal protein L3 | 0.061097 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0580897 |
| HDAC9 | histone deacetylase 9 | 0.0533205 |
| CCNL1 | cyclin L1 | 0.0527975 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.050356 |
| PCBP2 | poly(rC) binding protein 2 | 0.0461322 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0458129 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0429449 |
| RTN4 | reticulon 4 | 0.042733 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0423643 |
| NUP58 | nucleoporin 58 | 0.0405098 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0385185 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0379249 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0378995 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0373576 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0367864 |
| UBC | ubiquitin C | 0.0361524 |
| RPLP2 | ribosomal protein, large, P2 | 0.0352461 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.034774 |
| RPL21 | ribosomal protein L21 | 0.034409 |
| RPL23 | ribosomal protein L23 | 0.0325813 |
| SESN2 | sestrin 2 | 0.0323091 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0323005 |
| RPS12 | ribosomal protein S12 | 0.0315987 |
| PNN | pinin, desmosome associated protein | 0.0315693 |
| VMP1 | vacuole membrane protein 1 | 0.0309383 |
| ANK2 | ankyrin 2, neuronal | 0.0301572 |
| ZNF292 | zinc finger protein 292 | 0.0296134 |
| RPS6 | ribosomal protein S6 | 0.0291789 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0289708 |
| WDR43 | WD repeat domain 43 | 0.0285295 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0279464 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0273392 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0270697 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0266652 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0263211 |
| PLK2 | polo-like kinase 2 | 0.0259292 |
| TUBA1B | tubulin, alpha 1b | 0.0258115 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0253918 |
| NCKAP1 | NCK-associated protein 1 | 0.0253566 |
| MEF2A | myocyte enhancer factor 2A | 0.0252799 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0252011 |
| JMJD1C | jumonji domain containing 1C | 0.0251417 |
| HDGF | hepatoma-derived growth factor | 0.0248814 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0247506 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0240034 |
| BRD2 | bromodomain containing 2 | 0.0239758 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0236415 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0234246 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0231597 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0229702 |
| YAP1 | Yes-associated protein 1 | 0.022647 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0224929 |
| VEGFA | vascular endothelial growth factor A | 0.0221533 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0220534 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0220222 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0220017 |
| RPS3A | ribosomal protein S3A | 0.0219976 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0217453 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | 0.0216427 |
| DIAPH3 | diaphanous-related formin 3 | 0.0216208 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0215809 |
| CASC3 | cancer susceptibility candidate 3 | 0.0212992 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0212288 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0211544 |
| FAM168A | family with sequence similarity 168, member A | 0.0203334 |
| RPS2 | ribosomal protein S2 | 0.020219 |
| TXNRD1 | thioredoxin reductase 1 | 0.0202062 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0201852 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0201141 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.019942 |
| RPS3 | ribosomal protein S3 | 0.0198164 |
| QKI | QKI, KH domain containing, RNA binding | 0.0196431 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0195013 |
| SET | SET nuclear proto-oncogene | 0.0194344 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.019279 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0192601 |
| RPL37A | ribosomal protein L37a | 0.0190529 |
| CALR | calreticulin | 0.01865 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0185694 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0184918 |
| EZR | ezrin | 0.018437 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0184254 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0183864 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0182742 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0182575 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | 0.018133 |
| TPM3 | tropomyosin 3 | 0.0179734 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0179512 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0177108 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0174008 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0173027 |
| YTHDC1 | YTH domain containing 1 | 0.0168909 |
| PDGFC | platelet derived growth factor C | 0.0168069 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0167751 |
| PAPOLA | poly(A) polymerase alpha | 0.0166708 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0165543 |
| MED13L | mediator complex subunit 13-like | 0.0164952 |
| DAPK3 | death-associated protein kinase 3 | 0.016487 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.295548 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.227131 |
| VCL | vinculin | -0.153542 |
| LDHA | lactate dehydrogenase A | -0.115956 |
| PKM | pyruvate kinase, muscle | -0.106755 |
| AHNAK | AHNAK nucleoprotein | -0.106676 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.102045 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0965894 |
| NBEA | neurobeachin | -0.0891768 |
| ACTG1 | actin gamma 1 | -0.0859479 |
| TJP1 | tight junction protein 1 | -0.0831381 |
| PTMA | prothymosin, alpha | -0.0828902 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0817829 |
| CCND1 | cyclin D1 | -0.07773 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0772773 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0772461 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0735796 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0723415 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0679903 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.067747 |
| FOXP1 | forkhead box P1 | -0.0665935 |
| EFNA5 | ephrin-A5 | -0.0640923 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0639861 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0630757 |
| TMSB4X | thymosin beta 4, X-linked | -0.0619786 |
| PGK1 | phosphoglycerate kinase 1 | -0.0609709 |
| NFIA | nuclear factor I/A | -0.0580874 |
| RPL35A | ribosomal protein L35a | -0.0579908 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0560155 |
| TMEM65 | transmembrane protein 65 | -0.0556846 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0543386 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0541966 |
| S100A6 | S100 calcium binding protein A6 | -0.0536907 |
| HDLBP | high density lipoprotein binding protein | -0.053576 |
| PYGB | phosphorylase, glycogen; brain | -0.0520085 |
| BMP10 | bone morphogenetic protein 10 | -0.0517523 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.051607 |
| S100A4 | S100 calcium binding protein A4 | -0.0514251 |
| GLI2 | GLI family zinc finger 2 | -0.0494568 |
| CD47 | CD47 molecule | -0.0477228 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0469672 |
| RPLP1 | ribosomal protein, large, P1 | -0.0469042 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0451409 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0442629 |
| NF1 | neurofibromin 1 | -0.0439506 |
| SQSTM1 | sequestosome 1 | -0.0431971 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0430339 |
| EGFR | epidermal growth factor receptor | -0.0414756 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0408396 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0408355 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0403217 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0400768 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0397429 |
| ENOSF1 | enolase superfamily member 1 | -0.0393545 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0390754 |
| GNAS | GNAS complex locus | -0.0390084 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0373477 |
| FLNB | filamin B, beta | -0.0365655 |
| PRDX2 | peroxiredoxin 2 | -0.0363534 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0360439 |
| PRELID2 | PRELI domain containing 2 | -0.0354394 |
| SMYD3 | SET and MYND domain containing 3 | -0.0350121 |
| BMP2K | BMP2 inducible kinase | -0.0347457 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.034324 |
| FHIT | fragile histidine triad | -0.0339951 |
| RHOA | ras homolog family member A | -0.0336243 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0331567 |
| RPLP0 | ribosomal protein, large, P0 | -0.0329773 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0317398 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0316919 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0307886 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0307563 |
| MYO5C | myosin VC | -0.0305853 |
| CCDC68 | coiled-coil domain containing 68 | -0.0302675 |
| AHI1 | Abelson helper integration site 1 | -0.0302664 |
| ZNF608 | zinc finger protein 608 | -0.029902 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0297671 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.0296926 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0296825 |
| RRBP1 | ribosome binding protein 1 | -0.0293789 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0291085 |
| ALDOC | aldolase C, fructose-bisphosphate | -0.029088 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0289954 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | -0.0286264 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0285628 |
| LMAN1 | lectin, mannose-binding, 1 | -0.028196 |
| ENO1 | enolase 1, (alpha) | -0.0277222 |
| RPS24 | ribosomal protein S24 | -0.0276628 |
| S100A10 | S100 calcium binding protein A10 | -0.027047 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0269575 |
| METTL15 | methyltransferase like 15 | -0.0268361 |
| RPL34 | ribosomal protein L34 | -0.0267536 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0266885 |
| NBAS | neuroblastoma amplified sequence | -0.0265907 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0264095 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0262053 |
| DGKH | diacylglycerol kinase, eta | -0.0256559 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0255442 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0250397 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0247488 |
