| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.068896 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0432063 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0419258 |
| RPL37A | ribosomal protein L37a | 0.0388622 |
| RPS12 | ribosomal protein S12 | 0.0374101 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0332636 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0321072 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0311444 |
| RPL31 | ribosomal protein L31 | 0.0293169 |
| RPS3 | ribosomal protein S3 | 0.0288456 |
| RPLP2 | ribosomal protein, large, P2 | 0.0286009 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0274355 |
| KYNU | kynureninase | 0.0260901 |
| RPS8 | ribosomal protein S8 | 0.0252662 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0244517 |
| MX1 | MX dynamin-like GTPase 1 | 0.024205 |
| RPS27A | ribosomal protein S27a | 0.0240429 |
| RPS25 | ribosomal protein S25 | 0.0238753 |
| FLNA | filamin A, alpha | 0.022309 |
| GOLGB1 | golgin B1 | 0.0217834 |
| RPS29 | ribosomal protein S29 | 0.0214374 |
| RPL38 | ribosomal protein L38 | 0.020935 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0207358 |
| INTS6 | integrator complex subunit 6 | 0.0200893 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0187474 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.018571 |
| CALR | calreticulin | 0.0183506 |
| USP53 | ubiquitin specific peptidase 53 | 0.018212 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0177936 |
| RPL3 | ribosomal protein L3 | 0.017493 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.017356 |
| RPS2 | ribosomal protein S2 | 0.0170839 |
| RPS17 | ribosomal protein S17 | 0.0167535 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0162915 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0160886 |
| CFB | complement factor B | 0.0158558 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0158539 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0153759 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0149969 |
| CEP250 | centrosomal protein 250kDa | 0.0149901 |
| HSPA8 | heat shock 70kDa protein 8 | 0.014953 |
| PLEC | plectin | 0.0149125 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0145465 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0144603 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0144531 |
| RPL21 | ribosomal protein L21 | 0.0143793 |
| TPM3 | tropomyosin 3 | 0.0141208 |
| RPS27 | ribosomal protein S27 | 0.014044 |
| MKI67 | marker of proliferation Ki-67 | 0.0140192 |
| RPL13A | ribosomal protein L13a | 0.0138091 |
| SLFN5 | schlafen family member 5 | 0.013457 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.013422 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0133556 |
| KIF3B | kinesin family member 3B | 0.0132559 |
| DNER | delta/notch-like EGF repeat containing | 0.0132489 |
| DSPP | dentin sialophosphoprotein | 0.0129385 |
| KIAA1217 | KIAA1217 | 0.012928 |
| RPL5 | ribosomal protein L5 | 0.0128081 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0125509 |
| C3 | complement component 3 | 0.0125389 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0125136 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0124305 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.0123228 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0122342 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0122191 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0122115 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0121949 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0121074 |
| TUBA1B | tubulin, alpha 1b | 0.0120753 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0120651 |
| PGM3 | phosphoglucomutase 3 | 0.0119038 |
| VCP | valosin containing protein | 0.0118774 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.011584 |
| RPS6 | ribosomal protein S6 | 0.0115225 |
| CENPF | centromere protein F, 350/400kDa | 0.0115206 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0115193 |
| RPS16 | ribosomal protein S16 | 0.0113505 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0112968 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.01116 |
| CPNE1 | copine I | 0.0111334 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0111228 |
| PDCD5 | programmed cell death 5 | 0.0110725 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0110648 |
| MT1E | metallothionein 1E | 0.0109227 |
| RPS15A | ribosomal protein S15a | 0.0109219 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0108698 |
| LMO7 | LIM domain 7 | 0.0108626 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.010834 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0107817 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0107633 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0107353 |
| TRIM22 | tripartite motif containing 22 | 0.0107204 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0106364 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 0.0106259 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0105907 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0105152 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0104192 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0104043 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0103944 |
| TRIM25 | tripartite motif containing 25 | 0.0103662 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.323177 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.177729 |
| FRMD4A | FERM domain containing 4A | -0.158607 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.143485 |
| PGK1 | phosphoglycerate kinase 1 | -0.116563 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.111118 |
| COL6A3 | collagen, type VI, alpha 3 | -0.105387 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0985702 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0941372 |
| IER3 | immediate early response 3 | -0.0931811 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0891964 |
| CD44 | CD44 molecule (Indian blood group) | -0.0877914 |
| PDE10A | phosphodiesterase 10A | -0.0871949 |
| VCL | vinculin | -0.0849678 |
| LDHA | lactate dehydrogenase A | -0.0829485 |
| EGR1 | early growth response 1 | -0.0811845 |
| GLIS3 | GLIS family zinc finger 3 | -0.0786001 |
| ANXA2 | annexin A2 | -0.0737943 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0698692 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0673715 |
| MYOF | myoferlin | -0.0668576 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0636448 |
| TMSB10 | thymosin beta 10 | -0.0635623 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0629045 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0622873 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0622137 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0619982 |
| GNAS | GNAS complex locus | -0.0591069 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0570269 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0559408 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0558158 |
| B2M | beta-2-microglobulin | -0.0553771 |
| ZNF292 | zinc finger protein 292 | -0.0553302 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.055168 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0546554 |
| VCAN | versican | -0.0546442 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0528477 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0513389 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0500478 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0495254 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0493324 |
| TNS3 | tensin 3 | -0.0488601 |
| GPC6 | glypican 6 | -0.0482924 |
| CTSD | cathepsin D | -0.0471953 |
| DEK | DEK proto-oncogene | -0.0471403 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0471189 |
| FTL | ferritin, light polypeptide | -0.0470312 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.04699 |
| NAV1 | neuron navigator 1 | -0.0468798 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0468335 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0464421 |
| NDRG1 | N-myc downstream regulated 1 | -0.0461834 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0461771 |
| FN1 | fibronectin 1 | -0.0460789 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0460087 |
| STC1 | stanniocalcin 1 | -0.0457312 |
| HELZ | helicase with zinc finger | -0.0454148 |
| HLA-B | major histocompatibility complex, class I, B | -0.0447221 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0444782 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.044407 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.044348 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0443155 |
| RAI14 | retinoic acid induced 14 | -0.0413629 |
| CADM1 | cell adhesion molecule 1 | -0.0413181 |
| PLIN2 | perilipin 2 | -0.0410051 |
| HMGA1 | high mobility group AT-hook 1 | -0.0408654 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0404255 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0400505 |
| SEPTIN7 | septin 7 | -0.0395938 |
| ATP13A3 | ATPase type 13A3 | -0.0395747 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0395217 |
| RPS24 | ribosomal protein S24 | -0.0392569 |
| TKT | transketolase | -0.0389304 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0387436 |
| TMSB4X | thymosin beta 4, X-linked | -0.038525 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.037438 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.037007 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0368901 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0365808 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0364995 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0357411 |
| JUN | jun proto-oncogene | -0.0355029 |
| AHNAK | AHNAK nucleoprotein | -0.0353611 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0353387 |
| JMJD1C | jumonji domain containing 1C | -0.0353311 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0348352 |
| TMEM123 | transmembrane protein 123 | -0.0348269 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0341977 |
| ERBIN | erbb2 interacting protein | -0.034021 |
| KLF6 | Kruppel-like factor 6 | -0.0337062 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0327906 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0320013 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0319541 |
| COL1A1 | collagen, type I, alpha 1 | -0.0312731 |
| WTAP | Wilms tumor 1 associated protein | -0.0311138 |
| SNX9 | sorting nexin 9 | -0.0308885 |
| CDH13 | cadherin 13 | -0.0307886 |
| GOLGA4 | golgin A4 | -0.0307399 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0301604 |
| DIAPH2 | diaphanous-related formin 2 | -0.0300861 |
