| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.228318 |
| CDH13 | cadherin 13 | 0.0872267 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.07924 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0703293 |
| UBC | ubiquitin C | 0.0599611 |
| TMSB10 | thymosin beta 10 | 0.0486779 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.048233 |
| RPL37A | ribosomal protein L37a | 0.0463788 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0453298 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0445499 |
| RPS27A | ribosomal protein S27a | 0.0442755 |
| HELZ | helicase with zinc finger | 0.0442547 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0436147 |
| PTK2 | protein tyrosine kinase 2 | 0.0418579 |
| RPS19 | ribosomal protein S19 | 0.0414116 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0406009 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0389835 |
| TLK1 | tousled-like kinase 1 | 0.0385011 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0379821 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0379176 |
| KAZN | kazrin, periplakin interacting protein | 0.0373405 |
| FLNA | filamin A, alpha | 0.0371991 |
| FAM13A | family with sequence similarity 13, member A | 0.0371341 |
| ARMC9 | armadillo repeat containing 9 | 0.037072 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0370467 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0369992 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0367531 |
| ORC4 | origin recognition complex, subunit 4 | 0.0359421 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0358434 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0354735 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0350601 |
| RPS6 | ribosomal protein S6 | 0.0349494 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0348547 |
| DIDO1 | death inducer-obliterator 1 | 0.0343752 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.034293 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0338069 |
| DENND1A | DENN/MADD domain containing 1A | 0.0337758 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.033545 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0332102 |
| H1-0 | H1.0 linker histone | 0.0331904 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0331713 |
| RPL8 | ribosomal protein L8 | 0.0328328 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0328283 |
| RPS12 | ribosomal protein S12 | 0.032667 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.03265 |
| CUL4A | cullin 4A | 0.0322522 |
| TPI1 | triosephosphate isomerase 1 | 0.0321851 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0321563 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0318719 |
| EHBP1 | EH domain binding protein 1 | 0.031533 |
| RPL36A | ribosomal protein L36a | 0.0314043 |
| FNBP1L | formin binding protein 1-like | 0.0313772 |
| RPL12 | ribosomal protein L12 | 0.0312885 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0309772 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0309724 |
| AUTS2 | autism susceptibility candidate 2 | 0.0309247 |
| SPPL3 | signal peptide peptidase like 3 | 0.0308381 |
| FNBP4 | formin binding protein 4 | 0.0307533 |
| DST | dystonin | 0.0305744 |
| KYNU | kynureninase | 0.0304033 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | 0.0303085 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0300475 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.029915 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.029645 |
| RPS17 | ribosomal protein S17 | 0.0296026 |
| PHF3 | PHD finger protein 3 | 0.0294223 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0293495 |
| CANX | calnexin | 0.0292075 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0289443 |
| LSAMP | limbic system-associated membrane protein | 0.0288652 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0288197 |
| PDS5A | PDS5 cohesin associated factor A | 0.0287277 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0287211 |
| CD2AP | CD2-associated protein | 0.0285979 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0282846 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0278172 |
| VMP1 | vacuole membrane protein 1 | 0.0276555 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0276263 |
| PRKCA | protein kinase C, alpha | 0.0271778 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.0270001 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0266421 |
| SLC30A9 | solute carrier family 30 (zinc transporter), member 9 | 0.0265267 |
| PDGFC | platelet derived growth factor C | 0.0264985 |
| RPLP2 | ribosomal protein, large, P2 | 0.0263346 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0260427 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0260349 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0255515 |
| AHNAK | AHNAK nucleoprotein | 0.0255139 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0254524 |
| RPL10A | ribosomal protein L10a | 0.0253804 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.02537 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0252398 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0249866 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0249541 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0248465 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.0248429 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0246922 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0246718 |
| TBC1D22A | TBC1 domain family, member 22A | 0.024628 |
| RPL7A | ribosomal protein L7a | 0.0246115 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.273013 |
| B2M | beta-2-microglobulin | -0.205901 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.173144 |
| HLA-B | major histocompatibility complex, class I, B | -0.102927 |
| CD44 | CD44 molecule (Indian blood group) | -0.101782 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.100239 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0953654 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0893243 |
| LDHA | lactate dehydrogenase A | -0.078838 |
| MAP1B | microtubule-associated protein 1B | -0.0694019 |
| FN1 | fibronectin 1 | -0.0693341 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0671099 |
| ARRDC3 | arrestin domain containing 3 | -0.0669466 |
| H3-3B | H3.3 histone B | -0.0648699 |
| PKM | pyruvate kinase, muscle | -0.0610496 |
| COL6A3 | collagen, type VI, alpha 3 | -0.060609 |
| ZNF395 | zinc finger protein 395 | -0.0577642 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0541151 |
| SDC4 | syndecan 4 | -0.0526017 |
| RTN4 | reticulon 4 | -0.0525601 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0521593 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0517427 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.051688 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0512678 |
| SMAD3 | SMAD family member 3 | -0.0491411 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0489913 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0484011 |
| TXNIP | thioredoxin interacting protein | -0.0483253 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0464475 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0450737 |
| SETD5 | SET domain containing 5 | -0.045069 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0449531 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0449244 |
| FAM13B | family with sequence similarity 13, member B | -0.0441741 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0439748 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0432165 |
| CALD1 | caldesmon 1 | -0.0431782 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0429805 |
| VCL | vinculin | -0.0427206 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0421529 |
| SEPTIN7 | septin 7 | -0.0412088 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0410147 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0409665 |
| RRBP1 | ribosome binding protein 1 | -0.0408157 |
| LOXL2 | lysyl oxidase-like 2 | -0.040736 |
| STC1 | stanniocalcin 1 | -0.0402305 |
| COL1A1 | collagen, type I, alpha 1 | -0.0398019 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0396931 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0394805 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0394568 |
| SRPK2 | SRSF protein kinase 2 | -0.0390994 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0388337 |
| EGR1 | early growth response 1 | -0.0386313 |
| PTGES2 | prostaglandin E synthase 2 | -0.0380233 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0377364 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0376889 |
| HMGA2 | high mobility group AT-hook 2 | -0.0373504 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0372838 |
| STK17A | serine/threonine kinase 17a | -0.0372309 |
| PTN | pleiotrophin | -0.0368391 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.036529 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0364832 |
| MTPN | myotrophin | -0.0362441 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0362135 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | -0.035961 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0358486 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0355644 |
| RNF24 | ring finger protein 24 | -0.0353283 |
| POTEF | POTE ankyrin domain family, member F | -0.0353232 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0353185 |
| NBAS | neuroblastoma amplified sequence | -0.0352255 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0349087 |
| ACTG1 | actin gamma 1 | -0.0348197 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0347777 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0346099 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0344946 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0344273 |
| FNBP1 | formin binding protein 1 | -0.0343648 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0337796 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0336352 |
| PRSS23 | protease, serine, 23 | -0.0335423 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0333226 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0324523 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.03222 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0311275 |
| ECE1 | endothelin converting enzyme 1 | -0.0309727 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0308763 |
| TMEM131 | transmembrane protein 131 | -0.0305199 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0304436 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0301669 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0300948 |
| HMGB1 | high mobility group box 1 | -0.0300618 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.030043 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0299872 |
| FTL | ferritin, light polypeptide | -0.0296271 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | -0.0292917 |
| PALLD | palladin, cytoskeletal associated protein | -0.0291893 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.029054 |
| SEC24D | SEC24 family member D | -0.0289645 |
| FOSL1 | FOS-like antigen 1 | -0.0289165 |
