| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.0722403 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0506919 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0505798 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0491244 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0467081 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.046256 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0433132 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0419339 |
| RPL37A | ribosomal protein L37a | 0.0407329 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0399371 |
| TUBA1B | tubulin, alpha 1b | 0.0397164 |
| RPLP2 | ribosomal protein, large, P2 | 0.0392611 |
| RPS27A | ribosomal protein S27a | 0.037591 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0347811 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0346181 |
| RPS6 | ribosomal protein S6 | 0.0331517 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.0323668 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.032339 |
| KIAA1328 | KIAA1328 | 0.0320014 |
| RPL14 | ribosomal protein L14 | 0.0317236 |
| RPS17 | ribosomal protein S17 | 0.0309216 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0309052 |
| TUBB | tubulin, beta class I | 0.0307265 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0304113 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0299822 |
| UBB | ubiquitin B | 0.0294591 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0285586 |
| QSER1 | glutamine and serine rich 1 | 0.0285275 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0282727 |
| RPS3 | ribosomal protein S3 | 0.0275897 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0270319 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.026801 |
| RPL23 | ribosomal protein L23 | 0.0265922 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0262111 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0261188 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0260648 |
| CALR | calreticulin | 0.0256141 |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.0254884 |
| WDR43 | WD repeat domain 43 | 0.0249362 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0247342 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0246285 |
| THOC2 | THO complex 2 | 0.0245681 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0241392 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0238879 |
| RPL35 | ribosomal protein L35 | 0.0238601 |
| RAB18 | RAB18, member RAS oncogene family | 0.0238435 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0238186 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0236636 |
| SET | SET nuclear proto-oncogene | 0.0235741 |
| RPL21 | ribosomal protein L21 | 0.0235382 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0233551 |
| PDCD5 | programmed cell death 5 | 0.0231621 |
| PTTG1 | pituitary tumor-transforming 1 | 0.0225826 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0225564 |
| UBC | ubiquitin C | 0.0223468 |
| LYRM4 | LYR motif containing 4 | 0.022177 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | 0.0220355 |
| H2AZ1 | H2A.Z variant histone 1 | 0.0216839 |
| TMSB4X | thymosin beta 4, X-linked | 0.021448 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.021348 |
| HDGFL3 | HDGF like 3 | 0.0212426 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0211957 |
| PAPOLA | poly(A) polymerase alpha | 0.0210375 |
| KIAA0586 | KIAA0586 | 0.0209365 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0208929 |
| FANCI | Fanconi anemia, complementation group I | 0.0208499 |
| CEP192 | centrosomal protein 192kDa | 0.0207972 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0206961 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0206402 |
| TFCP2 | transcription factor CP2 | 0.0205752 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0204662 |
| CEP250 | centrosomal protein 250kDa | 0.0204655 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 0.0202106 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0201926 |
| AATF | apoptosis antagonizing transcription factor | 0.0200418 |
| ARHGAP11A | Rho GTPase activating protein 11A | 0.0200137 |
| RPL37 | ribosomal protein L37 | 0.0198888 |
| TUBA1C | tubulin, alpha 1c | 0.0197342 |
| PSMA4 | proteasome (prosome, macropain) subunit, alpha type, 4 | 0.0197282 |
| TRIM4 | tripartite motif containing 4 | 0.0196359 |
| KIF16B | kinesin family member 16B | 0.0195871 |
| TSPYL2 | TSPY-like 2 | 0.0195645 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0195444 |
| MAP1B | microtubule-associated protein 1B | 0.0194143 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.019362 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0193532 |
| HMGB1 | high mobility group box 1 | 0.0193386 |
| CNOT6 | CCR4-NOT transcription complex, subunit 6 | 0.0192627 |
| FSD1L | fibronectin type III and SPRY domain containing 1-like | 0.0192288 |
| TOP1 | topoisomerase (DNA) I | 0.0191823 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0191717 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0190945 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0190372 |
| PCBP2 | poly(rC) binding protein 2 | 0.0190139 |
| DYM | dymeclin | 0.0189692 |
| SQSTM1 | sequestosome 1 | 0.0189255 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.018734 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0186736 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0185433 |
| AHNAK | AHNAK nucleoprotein | 0.0184936 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.39068 |
| FNDC3B | fibronectin type III domain containing 3B | -0.123814 |
| LDHA | lactate dehydrogenase A | -0.106501 |
| SMYD3 | SET and MYND domain containing 3 | -0.10071 |
| MT2A | metallothionein 2A | -0.0972123 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.097096 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0956959 |
| CD44 | CD44 molecule (Indian blood group) | -0.0831637 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0809529 |
| YBX3 | Y box binding protein 3 | -0.0796732 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0784138 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.074925 |
| SNX14 | sorting nexin 14 | -0.0688635 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0633796 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0625569 |
| RPLP1 | ribosomal protein, large, P1 | -0.0622211 |
| POTEF | POTE ankyrin domain family, member F | -0.0621347 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0618501 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0610574 |
| SMAD3 | SMAD family member 3 | -0.0599085 |
| DEK | DEK proto-oncogene | -0.0594897 |
| TMSB10 | thymosin beta 10 | -0.0571477 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0566885 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0563208 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0558352 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0551074 |
| ATM | ATM serine/threonine kinase | -0.0528235 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0496669 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0485449 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0484036 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0481073 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0470201 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0466293 |
| DST | dystonin | -0.0464594 |
| ANLN | anillin, actin binding protein | -0.0456579 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0455231 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0451971 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0451847 |
| RBM39 | RNA binding motif protein 39 | -0.0450976 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0448483 |
| ANXA2 | annexin A2 | -0.0446307 |
| ATXN1 | ataxin 1 | -0.0439046 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0436096 |
| RTN4 | reticulon 4 | -0.0434699 |
| SPAG9 | sperm associated antigen 9 | -0.0427446 |
| FBXO11 | F-box protein 11 | -0.0426202 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0423884 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0422966 |
| TAOK1 | TAO kinase 1 | -0.0421495 |
| NF1 | neurofibromin 1 | -0.0420476 |
| GNAS | GNAS complex locus | -0.0420278 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0411407 |
| RDX | radixin | -0.0406218 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0404604 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0403299 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0402089 |
| ANGPTL4 | angiopoietin-like 4 | -0.0395653 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0387142 |
| VCL | vinculin | -0.038605 |
| NALCN | sodium leak channel, non selective | -0.0384686 |
| ANO6 | anoctamin 6 | -0.0375774 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0370958 |
| UBQLN1 | ubiquilin 1 | -0.0370706 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0364248 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0363772 |
| GOLGA4 | golgin A4 | -0.0363617 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0361846 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0360802 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0358885 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0358408 |
| CENPF | centromere protein F, 350/400kDa | -0.0357794 |
| PHF20 | PHD finger protein 20 | -0.0357149 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0353902 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0352149 |
| RIGI | RNA sensor RIG-I | -0.0352063 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0351801 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0345559 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0340263 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.033975 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0337395 |
| OGA | O-GlcNAcase | -0.0335454 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0335061 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0334111 |
| MSN | moesin | -0.0330638 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0322854 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0317677 |
| ANXA1 | annexin A1 | -0.0315754 |
| SETD5 | SET domain containing 5 | -0.0314996 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0312806 |
| NLK | nemo-like kinase | -0.03098 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0308994 |
| PTGES2 | prostaglandin E synthase 2 | -0.0308422 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0308334 |
| SDC4 | syndecan 4 | -0.0308251 |
| DNER | delta/notch-like EGF repeat containing | -0.0307133 |
| CLINT1 | clathrin interactor 1 | -0.0305765 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0304996 |
| RORA | RAR-related orphan receptor A | -0.0304873 |
| FRYL | FRY-like | -0.0303978 |
| USP34 | ubiquitin specific peptidase 34 | -0.0302793 |
