| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.0947029 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0732822 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0584342 |
| STC2 | stanniocalcin 2 | 0.0547738 |
| CENPF | centromere protein F, 350/400kDa | 0.0536067 |
| MKI67 | marker of proliferation Ki-67 | 0.0520541 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0419298 |
| RPS6 | ribosomal protein S6 | 0.0418935 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0412915 |
| HDGF | hepatoma-derived growth factor | 0.0405842 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0374086 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0322296 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.027587 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0254129 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0244059 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0238316 |
| RPL37A | ribosomal protein L37a | 0.0236215 |
| TMSB10 | thymosin beta 10 | 0.0228938 |
| CKAP2 | cytoskeleton associated protein 2 | 0.02289 |
| RPS27A | ribosomal protein S27a | 0.0227719 |
| CALR | calreticulin | 0.0226072 |
| RPS3 | ribosomal protein S3 | 0.0220435 |
| TPM3 | tropomyosin 3 | 0.0214592 |
| HMGB3 | high mobility group box 3 | 0.0196782 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0193573 |
| RPLP2 | ribosomal protein, large, P2 | 0.0192744 |
| RPL21 | ribosomal protein L21 | 0.0188362 |
| RPS12 | ribosomal protein S12 | 0.0185442 |
| RPS17 | ribosomal protein S17 | 0.0184565 |
| CBX3 | chromobox homolog 3 | 0.0181963 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0176018 |
| TPX2 | TPX2, microtubule-associated | 0.0170171 |
| RPL19 | ribosomal protein L19 | 0.0166968 |
| VIM | vimentin | 0.0164654 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0164595 |
| RPL31 | ribosomal protein L31 | 0.0162093 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.0159235 |
| H2AZ1 | H2A.Z variant histone 1 | 0.015906 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0155412 |
| PDCD5 | programmed cell death 5 | 0.0153097 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0152593 |
| TUBA1C | tubulin, alpha 1c | 0.0150336 |
| RPS27 | ribosomal protein S27 | 0.0147156 |
| TUBA1B | tubulin, alpha 1b | 0.0141749 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0140156 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0139215 |
| FLNA | filamin A, alpha | 0.0137913 |
| CCDC88A | coiled-coil domain containing 88A | 0.0137611 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0135862 |
| CENPE | centromere protein E, 312kDa | 0.0135155 |
| KIF14 | kinesin family member 14 | 0.0133078 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0132182 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0130446 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0129353 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0127108 |
| RPS8 | ribosomal protein S8 | 0.0125666 |
| SET | SET nuclear proto-oncogene | 0.0125261 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0124985 |
| RPS19 | ribosomal protein S19 | 0.0123731 |
| SGO2 | shugoshin 2 | 0.0122599 |
| LMO7 | LIM domain 7 | 0.0122358 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0122299 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0122261 |
| CKAP2L | cytoskeleton associated protein 2-like | 0.0119669 |
| RACK1 | receptor for activated C kinase 1 | 0.0119141 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0118692 |
| INTS6 | integrator complex subunit 6 | 0.0118036 |
| FOSL1 | FOS-like antigen 1 | 0.011704 |
| RPL5 | ribosomal protein L5 | 0.0116142 |
| PRR11 | proline rich 11 | 0.0116057 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.011578 |
| RPL11 | ribosomal protein L11 | 0.0114794 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.011413 |
| RPL23 | ribosomal protein L23 | 0.0113285 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0113174 |
| RPL3 | ribosomal protein L3 | 0.0112892 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0112045 |
| CCNB1 | cyclin B1 | 0.0111984 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0111975 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.011077 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0110232 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0110113 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.010718 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0107133 |
| PDAP1 | PDGFA associated protein 1 | 0.0107076 |
| RPS26 | ribosomal protein S26 | 0.0104657 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0103126 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0102835 |
| RPS25 | ribosomal protein S25 | 0.0101758 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0100836 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0100124 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.00997238 |
| RPL38 | ribosomal protein L38 | 0.00996346 |
| RPL36 | ribosomal protein L36 | 0.0099215 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0098086 |
| UBC | ubiquitin C | 0.00976117 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.00959584 |
| ARHGAP11A | Rho GTPase activating protein 11A | 0.00957221 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.00955428 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.00951057 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.31115 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.232648 |
| FN1 | fibronectin 1 | -0.223559 |
| EXT1 | exostosin glycosyltransferase 1 | -0.135361 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.132916 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.115475 |
| GLIS3 | GLIS family zinc finger 3 | -0.0849599 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0837064 |
| ITGA1 | integrin, alpha 1 | -0.0757403 |
| SQSTM1 | sequestosome 1 | -0.0752681 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0706343 |
| ASPH | aspartate beta-hydroxylase | -0.0701338 |
| VCL | vinculin | -0.066 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.064026 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0627451 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0583904 |
| EFNA5 | ephrin-A5 | -0.0571669 |
| NRP1 | neuropilin 1 | -0.056372 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0562023 |
| NRG1 | neuregulin 1 | -0.0551298 |
| AHR | aryl hydrocarbon receptor | -0.0539842 |
| TMEM156 | transmembrane protein 156 | -0.0538224 |
| OSMR | oncostatin M receptor | -0.0515752 |
| HMGA2 | high mobility group AT-hook 2 | -0.0515662 |
| SMAD3 | SMAD family member 3 | -0.0497064 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0489152 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0488948 |
| NDRG1 | N-myc downstream regulated 1 | -0.0487132 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0477425 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0474059 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0447736 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0444293 |
| RBM39 | RNA binding motif protein 39 | -0.0444282 |
| SYT1 | synaptotagmin I | -0.0436388 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0434623 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0430584 |
| TPR | translocated promoter region, nuclear basket protein | -0.0418394 |
| ACTN4 | actinin, alpha 4 | -0.0399597 |
| CANX | calnexin | -0.0396245 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0393141 |
| FNBP1 | formin binding protein 1 | -0.039227 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0389069 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0388906 |
| PELO | pelota homolog (Drosophila) | -0.0387788 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0385581 |
| ETV6 | ets variant 6 | -0.0380139 |
| SMYD3 | SET and MYND domain containing 3 | -0.0378897 |
| RUNX2 | runt-related transcription factor 2 | -0.037781 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0374616 |
| CD109 | CD109 molecule | -0.0371293 |
| CDC73 | cell division cycle 73 | -0.0364013 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0352886 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0349056 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0334534 |
| EREG | epiregulin | -0.0330872 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.032985 |
| FOXP1 | forkhead box P1 | -0.0326509 |
| DST | dystonin | -0.0322767 |
| ETV1 | ets variant 1 | -0.0322609 |
| COPA | coatomer protein complex, subunit alpha | -0.0319947 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0319123 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0318438 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0314584 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0313945 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0313861 |
| OGA | O-GlcNAcase | -0.0306235 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0303907 |
| DENND5B | DENN/MADD domain containing 5B | -0.0299881 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0299689 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0298062 |
| CD44 | CD44 molecule (Indian blood group) | -0.0297673 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0294534 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0291817 |
| SPAG9 | sperm associated antigen 9 | -0.028917 |
| PTK2 | protein tyrosine kinase 2 | -0.0286995 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.02827 |
| RAB31 | RAB31, member RAS oncogene family | -0.0281824 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0280564 |
| NEK7 | NIMA-related kinase 7 | -0.028047 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.028041 |
| ARF1 | ADP-ribosylation factor 1 | -0.0279624 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0278378 |
| SMOX | spermine oxidase | -0.0277691 |
| ETNK1 | ethanolamine kinase 1 | -0.0275793 |
| ZNF217 | zinc finger protein 217 | -0.0275776 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0275049 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0273352 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0272214 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0270965 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0270751 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.026971 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0268989 |
| CALU | calumenin | -0.0265481 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0264546 |
| HPCAL1 | hippocalcin-like 1 | -0.0263999 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0262388 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0259702 |
| RRBP1 | ribosome binding protein 1 | -0.0259502 |
| HLA-B | major histocompatibility complex, class I, B | -0.0257828 |
| CLTC | clathrin, heavy chain (Hc) | -0.0257313 |
