| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | 0.0520341 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0498341 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0411437 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0406127 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0370163 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0359491 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0333753 |
| PTMA | prothymosin, alpha | 0.0332713 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0310583 |
| PCBP2 | poly(rC) binding protein 2 | 0.030555 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0302218 |
| HLA-A | major histocompatibility complex, class I, A | 0.0301949 |
| NDRG1 | N-myc downstream regulated 1 | 0.0298879 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0294993 |
| SET | SET nuclear proto-oncogene | 0.0290676 |
| VEGFA | vascular endothelial growth factor A | 0.0289275 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0284158 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0277181 |
| HDGF | hepatoma-derived growth factor | 0.0271821 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0265254 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0257247 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0253351 |
| RPL3 | ribosomal protein L3 | 0.0234906 |
| TPM3 | tropomyosin 3 | 0.023123 |
| CADPS | Ca++-dependent secretion activator | 0.0228947 |
| CCNL1 | cyclin L1 | 0.0228355 |
| RCOR1 | REST corepressor 1 | 0.022781 |
| ADM | adrenomedullin | 0.0221576 |
| CALR | calreticulin | 0.0213849 |
| STC2 | stanniocalcin 2 | 0.0210655 |
| VASP | vasodilator-stimulated phosphoprotein | 0.0210148 |
| PNN | pinin, desmosome associated protein | 0.0209948 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0207576 |
| RPL21 | ribosomal protein L21 | 0.0195305 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0195239 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.019445 |
| HYOU1 | hypoxia up-regulated 1 | 0.0182358 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0177874 |
| RPS12 | ribosomal protein S12 | 0.017658 |
| ASPH | aspartate beta-hydroxylase | 0.0169541 |
| TMF1 | TATA element modulatory factor 1 | 0.016672 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0163244 |
| DYNLL2 | dynein, light chain, LC8-type 2 | 0.0160136 |
| VIM | vimentin | 0.0159602 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0159431 |
| SSRP1 | structure specific recognition protein 1 | 0.0155769 |
| MXD1 | MAX dimerization protein 1 | 0.0154554 |
| PCDH1 | protocadherin 1 | 0.0154099 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0149847 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0148614 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0144815 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0144489 |
| HBEGF | heparin-binding EGF-like growth factor | 0.0142987 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.014253 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.0141832 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0140008 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0139245 |
| FLNA | filamin A, alpha | 0.0139098 |
| YY1 | YY1 transcription factor | 0.0138095 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0136287 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0135617 |
| ATF4 | activating transcription factor 4 | 0.013418 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0133462 |
| RPS3A | ribosomal protein S3A | 0.0133102 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0131217 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0130495 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0127699 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 0.0127647 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.012672 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0125719 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0124254 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0123695 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0122213 |
| UNC13A | unc-13 homolog A (C. elegans) | 0.0121082 |
| RPL9 | ribosomal protein L9 | 0.0120914 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | 0.0119742 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0119462 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0119006 |
| CDK19 | cyclin-dependent kinase 19 | 0.0118852 |
| XPOT | exportin, tRNA | 0.0117395 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0117232 |
| DSTN | destrin (actin depolymerizing factor) | 0.0117055 |
| MSN | moesin | 0.0116974 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.011662 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0116543 |
| GPC6 | glypican 6 | 0.0116054 |
| CHMP4B | charged multivesicular body protein 4B | 0.0115776 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0114586 |
| PAPOLA | poly(A) polymerase alpha | 0.0114529 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0114121 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0113042 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0112482 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0112148 |
| NCKIPSD | NCK interacting protein with SH3 domain | 0.0111416 |
| ENO1 | enolase 1, (alpha) | 0.0110876 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.011056 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.01088 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0107183 |
| PDAP1 | PDGFA associated protein 1 | 0.0107071 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.010583 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.140862 |
| ACTN4 | actinin, alpha 4 | -0.114281 |
| ANXA2 | annexin A2 | -0.106846 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.105601 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.105161 |
| KRT8 | keratin 8, type II | -0.100139 |
| EZR | ezrin | -0.0971155 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0923736 |
| H1-0 | H1.0 linker histone | -0.0911239 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0905177 |
| BCL2L1 | BCL2-like 1 | -0.0826364 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0798052 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0795292 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0795003 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0759666 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0750086 |
| MYOF | myoferlin | -0.0656054 |
| RHEB | Ras homolog enriched in brain | -0.0634489 |
| FTL | ferritin, light polypeptide | -0.0633053 |
| TMSB10 | thymosin beta 10 | -0.0603734 |
| SDC4 | syndecan 4 | -0.0602431 |
| RPS21 | ribosomal protein S21 | -0.0592221 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0562919 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.055291 |
| PRELID2 | PRELI domain containing 2 | -0.0552695 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0551549 |
| FAM3C | family with sequence similarity 3, member C | -0.0541853 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0540666 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0534985 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0528982 |
| VCL | vinculin | -0.0523415 |
| GNAS | GNAS complex locus | -0.0517226 |
| SERINC5 | serine incorporator 5 | -0.0513811 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0510785 |
| SNX9 | sorting nexin 9 | -0.0480893 |
| JMJD1C | jumonji domain containing 1C | -0.0479596 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0478855 |
| IER3 | immediate early response 3 | -0.0473312 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0470928 |
| RBM39 | RNA binding motif protein 39 | -0.0469692 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.046948 |
| RPLP1 | ribosomal protein, large, P1 | -0.0463193 |
| CCND1 | cyclin D1 | -0.0460898 |
| AHNAK | AHNAK nucleoprotein | -0.0450478 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0447217 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0432151 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0431222 |
| TOP1 | topoisomerase (DNA) I | -0.0428962 |
| FRMD5 | FERM domain containing 5 | -0.0422967 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.042225 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0420226 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0417801 |
| MATR3 | matrin 3 | -0.0415226 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0412408 |
| NEK7 | NIMA-related kinase 7 | -0.0401073 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0399962 |
| NF1 | neurofibromin 1 | -0.0398744 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0398463 |
| KRT18 | keratin 18, type I | -0.0398201 |
| VMP1 | vacuole membrane protein 1 | -0.039723 |
| RPL35A | ribosomal protein L35a | -0.0394075 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0394015 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0393576 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0392932 |
| SQSTM1 | sequestosome 1 | -0.0392777 |
| AFDN | afadin, adherens junction formation factor | -0.0390212 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0388529 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0387544 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0381091 |
| STK4 | serine/threonine kinase 4 | -0.038064 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0378214 |
| ZNF217 | zinc finger protein 217 | -0.0377548 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0376849 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0376478 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0373371 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0371514 |
| APP | amyloid beta (A4) precursor protein | -0.0369384 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0366244 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0363134 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0362185 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0362162 |
| WWC1 | WW and C2 domain containing 1 | -0.0360212 |
| LDHA | lactate dehydrogenase A | -0.0359247 |
| OGA | O-GlcNAcase | -0.0357964 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.035147 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0351012 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0349735 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0344896 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0344893 |
| PLAUR | plasminogen activator, urokinase receptor | -0.03416 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0338495 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0337022 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.033471 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0334482 |
| TMEM123 | transmembrane protein 123 | -0.0332613 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0332604 |
| NEBL | nebulette | -0.0331492 |
| EPCAM | epithelial cell adhesion molecule | -0.0329798 |
| IPO7 | importin 7 | -0.0328733 |
| PLSCR1 | phospholipid scramblase 1 | -0.0328481 |
