| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Docetaxel (Trihydrate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MKI67 | marker of proliferation Ki-67 | 0.0259808 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0224386 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0222836 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0212709 |
| RPLP2 | ribosomal protein, large, P2 | 0.0196752 |
| HSPA8 | heat shock 70kDa protein 8 | 0.01935 |
| RPL13A | ribosomal protein L13a | 0.0188092 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.018519 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0182413 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0159966 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0158888 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.015474 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0152625 |
| RPS6 | ribosomal protein S6 | 0.0150711 |
| ZBTB7C | zinc finger and BTB domain containing 7C | 0.0150268 |
| RPS12 | ribosomal protein S12 | 0.0149678 |
| MYO5B | myosin VB | 0.0134465 |
| H1-4 | H1.4 linker histone, cluster member | 0.013434 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0134175 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0123572 |
| RPS17 | ribosomal protein S17 | 0.0121683 |
| RPL37A | ribosomal protein L37a | 0.0121039 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0120847 |
| KLC1 | kinesin light chain 1 | 0.0120778 |
| RPL3 | ribosomal protein L3 | 0.0118486 |
| FMNL2 | formin-like 2 | 0.0113222 |
| SLK | STE20-like kinase | 0.0107939 |
| RREB1 | ras responsive element binding protein 1 | 0.010558 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0103659 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0103466 |
| TXNRD1 | thioredoxin reductase 1 | 0.0103154 |
| XPOT | exportin, tRNA | 0.0102049 |
| ABHD3 | abhydrolase domain containing 3 | 0.00993723 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 | 0.00974572 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | 0.00957838 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.00937523 |
| RPL38 | ribosomal protein L38 | 0.00922187 |
| PSPC1 | paraspeckle component 1 | 0.00920072 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.00918842 |
| CKAP2 | cytoskeleton associated protein 2 | 0.00895597 |
| FN1 | fibronectin 1 | 0.00893976 |
| NFXL1 | nuclear transcription factor, X-box binding-like 1 | 0.00892382 |
| RPL32 | ribosomal protein L32 | 0.00890177 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00889105 |
| CCNC | cyclin C | 0.00883167 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.00871153 |
| RSL24D1 | ribosomal L24 domain containing 1 | 0.00870224 |
| RPL21 | ribosomal protein L21 | 0.0086583 |
| MTAP | methylthioadenosine phosphorylase | 0.00857575 |
| LBR | lamin B receptor | 0.00854198 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00848953 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | 0.00831307 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.00831274 |
| TUBB | tubulin, beta class I | 0.00828529 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.00821221 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0080806 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.00807168 |
| STRN4 | striatin, calmodulin binding protein 4 | 0.00803106 |
| CREB5 | cAMP responsive element binding protein 5 | 0.00801425 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.00778578 |
| GAK | cyclin G associated kinase | 0.00768949 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.00768422 |
| RPS24 | ribosomal protein S24 | 0.00767054 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00765345 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.00762479 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.00759522 |
| STIP1 | stress-induced phosphoprotein 1 | 0.00759414 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.00751695 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.00751418 |
| SEM1 | SEM1 26S proteasome subunit | 0.00748174 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.00744637 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.00743044 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.00741578 |
| SRFBP1 | serum response factor binding protein 1 | 0.00741234 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | 0.00741199 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0073707 |
| EPS8L2 | EPS8-like 2 | 0.00735665 |
| FDPS | farnesyl diphosphate synthase | 0.00729844 |
| PDAP1 | PDGFA associated protein 1 | 0.00728662 |
| TMED7 | transmembrane emp24 protein transport domain containing 7 | 0.00727819 |
| LYAR | Ly1 antibody reactive | 0.00725579 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.00725529 |
| MAOB | monoamine oxidase B | 0.00721694 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.00720714 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.00719607 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | 0.00719556 |
| RBM17 | RNA binding motif protein 17 | 0.00719136 |
| PYGB | phosphorylase, glycogen; brain | 0.00711182 |
| H1-2 | H1.2 linker histone, cluster member | 0.00710378 |
| RPS3A | ribosomal protein S3A | 0.00707421 |
| COL5A2 | collagen, type V, alpha 2 | 0.00698597 |
| SAFB | scaffold attachment factor B | 0.00698557 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein | 0.00696671 |
| PARK7 | parkinson protein 7 | 0.00696486 |
| TMSB4X | thymosin beta 4, X-linked | 0.00693538 |
| BBX | bobby sox homolog (Drosophila) | 0.00692789 |
| NCKAP1 | NCK-associated protein 1 | 0.00690924 |
| ZNF706 | zinc finger protein 706 | 0.00690737 |
| RPL41 | ribosomal protein L41 | 0.00688162 |
| WDR75 | WD repeat domain 75 | 0.00687072 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.129829 |
| AREG | amphiregulin | -0.11242 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.110367 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.10471 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0947124 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0843785 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0835756 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0724255 |
| TMSB10 | thymosin beta 10 | -0.0717399 |
| EGFR | epidermal growth factor receptor | -0.0708958 |
| LDHA | lactate dehydrogenase A | -0.0700281 |
| ATXN1 | ataxin 1 | -0.0654361 |
| UBC | ubiquitin C | -0.0637534 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.058976 |
| EZR | ezrin | -0.0578184 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0572452 |
| ACTG1 | actin gamma 1 | -0.0556043 |
| ANXA1 | annexin A1 | -0.0531446 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0500981 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0474198 |
| EGR1 | early growth response 1 | -0.0464559 |
| OXR1 | oxidation resistance 1 | -0.0461252 |
| IER3 | immediate early response 3 | -0.0434734 |
| PCBP2 | poly(rC) binding protein 2 | -0.0427302 |
| AHNAK | AHNAK nucleoprotein | -0.042576 |
| ACTN4 | actinin, alpha 4 | -0.0422451 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0410001 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0408768 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0406746 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.039477 |
| FAT1 | FAT atypical cadherin 1 | -0.0390534 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0375684 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0374451 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0368091 |
| CD9 | CD9 molecule | -0.0367995 |
| HMGA1 | high mobility group AT-hook 1 | -0.0348472 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0345102 |
| ENO1 | enolase 1, (alpha) | -0.0342575 |
| VMP1 | vacuole membrane protein 1 | -0.0338789 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0337198 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0329019 |
| ZNF292 | zinc finger protein 292 | -0.0319896 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0313652 |
| EMP1 | epithelial membrane protein 1 | -0.0309894 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0305289 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0298756 |
| LMO7 | LIM domain 7 | -0.0292379 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0290386 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0289551 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0283038 |
| RPS27A | ribosomal protein S27a | -0.0282446 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0280062 |
| HMGA2 | high mobility group AT-hook 2 | -0.0277839 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0273346 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0272744 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0268758 |
| LAMC2 | laminin, gamma 2 | -0.0267666 |
| CPOX | coproporphyrinogen oxidase | -0.0265443 |
| YAP1 | Yes-associated protein 1 | -0.0262738 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0261249 |
| LAMB3 | laminin, beta 3 | -0.0258566 |
| SDC4 | syndecan 4 | -0.0255779 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0254975 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0254454 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0253751 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0253422 |
| S100A10 | S100 calcium binding protein A10 | -0.0248917 |
| TXNIP | thioredoxin interacting protein | -0.0248004 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0246834 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0246623 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0245987 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0244898 |
| POTEF | POTE ankyrin domain family, member F | -0.0244382 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0242369 |
| HLA-B | major histocompatibility complex, class I, B | -0.0237623 |
| PKM | pyruvate kinase, muscle | -0.0235632 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0233311 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0229918 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0229807 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0229775 |
| CALU | calumenin | -0.0228831 |
| MED13L | mediator complex subunit 13-like | -0.0228791 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0227355 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0226951 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0226768 |
| RAD51B | RAD51 paralog B | -0.0223211 |
| SEPTIN7 | septin 7 | -0.0222434 |
| S100A6 | S100 calcium binding protein A6 | -0.0220393 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0218368 |
| PERP | PERP, TP53 apoptosis effector | -0.0217968 |
| CD44 | CD44 molecule (Indian blood group) | -0.0215367 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0215219 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0206858 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0205913 |
| SYAP1 | synapse associated protein 1 | -0.0202352 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0202279 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0202013 |
| RPLP1 | ribosomal protein, large, P1 | -0.0200283 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0199519 |
| ATL2 | atlastin GTPase 2 | -0.0199381 |
