| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH13 | cadherin 13 | 0.169431 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0903805 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0761067 |
| RPS12 | ribosomal protein S12 | 0.0732623 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0731168 |
| H1-0 | H1.0 linker histone | 0.0624587 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0604898 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0590016 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0583421 |
| FLNA | filamin A, alpha | 0.056165 |
| RPS3 | ribosomal protein S3 | 0.0549011 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0545644 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0542746 |
| RPL37A | ribosomal protein L37a | 0.0527533 |
| ITGA6 | integrin, alpha 6 | 0.0518207 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0471498 |
| FLNB | filamin B, beta | 0.0470323 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0446395 |
| RPLP2 | ribosomal protein, large, P2 | 0.0440858 |
| RPS25 | ribosomal protein S25 | 0.0438836 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0431568 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0424268 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0413014 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0410179 |
| RPS17 | ribosomal protein S17 | 0.0406207 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0405471 |
| RPS27A | ribosomal protein S27a | 0.0401377 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0396635 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0395028 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0391108 |
| COG5 | component of oligomeric golgi complex 5 | 0.0382489 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0377633 |
| RPL23 | ribosomal protein L23 | 0.0375137 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0351627 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0348848 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0346642 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0344881 |
| STC2 | stanniocalcin 2 | 0.0342396 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0338763 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0338296 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0330685 |
| TMSB10 | thymosin beta 10 | 0.0330541 |
| RPL5 | ribosomal protein L5 | 0.0330042 |
| ETNK1 | ethanolamine kinase 1 | 0.0319587 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0318417 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0318151 |
| ENO1 | enolase 1, (alpha) | 0.0317886 |
| RPL3 | ribosomal protein L3 | 0.0307834 |
| RPL19 | ribosomal protein L19 | 0.0304507 |
| RPL4 | ribosomal protein L4 | 0.029682 |
| RPL12 | ribosomal protein L12 | 0.0295546 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0294446 |
| RASA3 | RAS p21 protein activator 3 | 0.0294197 |
| CALR | calreticulin | 0.0293911 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.029336 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0291805 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0289737 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0286748 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0285671 |
| PLEC | plectin | 0.0285562 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0285358 |
| AFDN | afadin, adherens junction formation factor | 0.0282155 |
| LARP1 | La ribonucleoprotein domain family, member 1 | 0.0281052 |
| PCBP2 | poly(rC) binding protein 2 | 0.0278846 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0274853 |
| TMSB4X | thymosin beta 4, X-linked | 0.0274461 |
| TBC1D5 | TBC1 domain family, member 5 | 0.027309 |
| CTBP2 | C-terminal binding protein 2 | 0.0271073 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0268489 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0267415 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0267394 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | 0.0261957 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0260764 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0253049 |
| RPL32 | ribosomal protein L32 | 0.025138 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0250195 |
| OLA1 | Obg-like ATPase 1 | 0.0249626 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0240603 |
| CDK6 | cyclin-dependent kinase 6 | 0.0240562 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0240341 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0238917 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0238251 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0236513 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0235444 |
| FMNL2 | formin-like 2 | 0.0234419 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0234034 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0233763 |
| RPL38 | ribosomal protein L38 | 0.0233579 |
| SYT1 | synaptotagmin I | 0.0233442 |
| RPS15A | ribosomal protein S15a | 0.023324 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0232282 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0230824 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0228401 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0227208 |
| CMIP | c-Maf inducing protein | 0.0226975 |
| SLMAP | sarcolemma associated protein | 0.0226084 |
| RPL13A | ribosomal protein L13a | 0.0225345 |
| RPL26 | ribosomal protein L26 | 0.0224799 |
| RPS4X | ribosomal protein S4, X-linked | 0.02241 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0223959 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.164195 |
| EZR | ezrin | -0.0985379 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0908764 |
| LDHA | lactate dehydrogenase A | -0.0885892 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0791736 |
| MT2A | metallothionein 2A | -0.0760687 |
| ACTN4 | actinin, alpha 4 | -0.0720512 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0669497 |
| HMGA1 | high mobility group AT-hook 1 | -0.0667034 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0646109 |
| OXR1 | oxidation resistance 1 | -0.0605095 |
| PTMA | prothymosin, alpha | -0.0604624 |
| CENPF | centromere protein F, 350/400kDa | -0.0591113 |
| YAP1 | Yes-associated protein 1 | -0.0577566 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0570686 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0568384 |
| DUSP6 | dual specificity phosphatase 6 | -0.0567756 |
| RPL7 | ribosomal protein L7 | -0.0547919 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0542268 |
| DSPP | dentin sialophosphoprotein | -0.0538234 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0534749 |
| EGR1 | early growth response 1 | -0.0514525 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0512041 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0500398 |
| ACTG1 | actin gamma 1 | -0.0495 |
| LMO7 | LIM domain 7 | -0.0493077 |
| BCL2L1 | BCL2-like 1 | -0.0489642 |
| RPS2 | ribosomal protein S2 | -0.0485529 |
| DEK | DEK proto-oncogene | -0.0480608 |
| POTEF | POTE ankyrin domain family, member F | -0.0477634 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0474407 |
| SEPTIN9 | septin 9 | -0.0467879 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0464137 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0449216 |
| PGK1 | phosphoglycerate kinase 1 | -0.0446024 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.0445243 |
| RBM39 | RNA binding motif protein 39 | -0.0443805 |
| SMAD3 | SMAD family member 3 | -0.0442542 |
| TXNIP | thioredoxin interacting protein | -0.0441916 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | -0.0441554 |
| RPL35A | ribosomal protein L35a | -0.0434865 |
| HMGB2 | high mobility group box 2 | -0.0432868 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0423267 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0421098 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0415149 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.041243 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0406365 |
| VCL | vinculin | -0.0401905 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0394812 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0394701 |
| H3-3B | H3.3 histone B | -0.0394661 |
| RPLP1 | ribosomal protein, large, P1 | -0.039102 |
| YBX3 | Y box binding protein 3 | -0.0385462 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0384808 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0379127 |
| ACTN1 | actinin, alpha 1 | -0.0372231 |
| GLI3 | GLI family zinc finger 3 | -0.0367435 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0364673 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0362862 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.03601 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0359224 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0357582 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.035617 |
| EMP1 | epithelial membrane protein 1 | -0.0356168 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0352938 |
| CLTC | clathrin, heavy chain (Hc) | -0.0352584 |
| AXIN2 | axin 2 | -0.0349029 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0347015 |
| RNF43 | ring finger protein 43 | -0.0345729 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0343334 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0339848 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0339315 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0337318 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0336741 |
| PERP | PERP, TP53 apoptosis effector | -0.0335023 |
| UBXN4 | UBX domain protein 4 | -0.0333736 |
| AOPEP | aminopeptidase O (putative) | -0.0332111 |
| CCND1 | cyclin D1 | -0.0328779 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0328448 |
| RRM2 | ribonucleotide reductase M2 | -0.0327557 |
| RTN3 | reticulon 3 | -0.0319405 |
| DST | dystonin | -0.0316973 |
| EXPH5 | exophilin 5 | -0.0314349 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0313066 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0312358 |
| MKI67 | marker of proliferation Ki-67 | -0.0309481 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0308238 |
| DIAPH3 | diaphanous-related formin 3 | -0.0307332 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0305237 |
| BMP5 | bone morphogenetic protein 5 | -0.0304301 |
| ATXN1 | ataxin 1 | -0.030356 |
| TNS4 | tensin 4 | -0.0303309 |
| ANLN | anillin, actin binding protein | -0.0302545 |
| CKAP5 | cytoskeleton associated protein 5 | -0.030034 |
| RBP1 | retinol binding protein 1, cellular | -0.0299307 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0298873 |
| IPO7 | importin 7 | -0.0298289 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0298039 |
| ANO6 | anoctamin 6 | -0.0297845 |
| THOC2 | THO complex 2 | -0.0291218 |
