| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Docetaxel_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.126032 |
| NDRG1 | N-myc downstream regulated 1 | 0.0895051 |
| STC1 | stanniocalcin 1 | 0.0886412 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0770967 |
| VEGFC | vascular endothelial growth factor C | 0.0728123 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0699187 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0552134 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0536946 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0521402 |
| MYADM | myeloid-associated differentiation marker | 0.0487965 |
| VCL | vinculin | 0.0461194 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0455701 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0451932 |
| SUCNR1 | succinate receptor 1 | 0.045191 |
| FLNA | filamin A, alpha | 0.0450524 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0442951 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.044203 |
| HDAC9 | histone deacetylase 9 | 0.0441326 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0436246 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0413268 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0400436 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0397681 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0390709 |
| RACK1 | receptor for activated C kinase 1 | 0.0390467 |
| SP100 | SP100 nuclear antigen | 0.0386559 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0381502 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0380671 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0376021 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0370272 |
| PODXL | podocalyxin-like | 0.036514 |
| NIBAN2 | niban apoptosis regulator 2 | 0.036357 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0352126 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0343146 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0342696 |
| MCL1 | myeloid cell leukemia 1 | 0.0312555 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0299593 |
| AUTS2 | autism susceptibility candidate 2 | 0.0287015 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0285284 |
| SEPTIN9 | septin 9 | 0.0283864 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0283638 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.028265 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0280188 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0279964 |
| UBAP1 | ubiquitin associated protein 1 | 0.0271817 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0271762 |
| RUNX1 | runt-related transcription factor 1 | 0.0267941 |
| EGR1 | early growth response 1 | 0.0267634 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.026491 |
| TPM3 | tropomyosin 3 | 0.0263807 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0261153 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0258315 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0254721 |
| FOXP1 | forkhead box P1 | 0.0253596 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0252903 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0249522 |
| PTK2 | protein tyrosine kinase 2 | 0.0249078 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0247278 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.02453 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0241685 |
| EZR | ezrin | 0.024139 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0240472 |
| ZNF148 | zinc finger protein 148 | 0.0239989 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0236854 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0234286 |
| SMAD3 | SMAD family member 3 | 0.0232537 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0232052 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0230414 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.023003 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0229604 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0227623 |
| ARRDC3 | arrestin domain containing 3 | 0.0227295 |
| TLE4 | transducin-like enhancer of split 4 | 0.0226529 |
| TAPBP | TAP binding protein (tapasin) | 0.0219954 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0218364 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0217736 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0216913 |
| MX2 | MX dynamin-like GTPase 2 | 0.021618 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0215769 |
| TXNRD1 | thioredoxin reductase 1 | 0.021382 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0213788 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.021033 |
| LDHA | lactate dehydrogenase A | 0.0208437 |
| SATB2 | SATB homeobox 2 | 0.0208059 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0208005 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0206978 |
| INTS6 | integrator complex subunit 6 | 0.0206854 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0206663 |
| JUN | jun proto-oncogene | 0.0206361 |
| KLF10 | Kruppel-like factor 10 | 0.0206221 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0204386 |
| IFI44L | interferon-induced protein 44-like | 0.0202059 |
| JMJD1C | jumonji domain containing 1C | 0.0201814 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0199548 |
| TXNIP | thioredoxin interacting protein | 0.0198789 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0198498 |
| FAT1 | FAT atypical cadherin 1 | 0.0197525 |
| TUBA1B | tubulin, alpha 1b | 0.0196296 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0195075 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.019417 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.019327 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.199529 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.193848 |
| COL5A1 | collagen, type V, alpha 1 | -0.150652 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.144817 |
| VIM | vimentin | -0.144642 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.129425 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.127362 |
| AHNAK | AHNAK nucleoprotein | -0.123398 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.119607 |
| TMSB10 | thymosin beta 10 | -0.115018 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.105046 |
| COL5A2 | collagen, type V, alpha 2 | -0.0975545 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0868293 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0837653 |
| MYOF | myoferlin | -0.080913 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0758996 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0707299 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0687355 |
| FN1 | fibronectin 1 | -0.0666658 |
| CDH13 | cadherin 13 | -0.065277 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0595808 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0552672 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0505219 |
| COL3A1 | collagen, type III, alpha 1 | -0.0505125 |
| RRBP1 | ribosome binding protein 1 | -0.0484258 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0480828 |
| EGFR | epidermal growth factor receptor | -0.0480642 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0468639 |
| CANX | calnexin | -0.0462341 |
| LMNA | lamin A/C | -0.0459604 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0454213 |
| SBF2 | SET binding factor 2 | -0.0449384 |
| COL1A2 | collagen, type I, alpha 2 | -0.0444428 |
| RAI14 | retinoic acid induced 14 | -0.0429534 |
| S100A10 | S100 calcium binding protein A10 | -0.0429161 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0415046 |
| LOXL2 | lysyl oxidase-like 2 | -0.0414786 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0414168 |
| FBN1 | fibrillin 1 | -0.0405601 |
| IL7R | interleukin 7 receptor | -0.0401485 |
| HLA-B | major histocompatibility complex, class I, B | -0.0378646 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0375457 |
| ANXA2 | annexin A2 | -0.0374946 |
| CSTB | cystatin B (stefin B) | -0.0374464 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0374131 |
| NAV1 | neuron navigator 1 | -0.0368709 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0368242 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0356923 |
| TENM3 | teneurin transmembrane protein 3 | -0.0353187 |
| GOLGA4 | golgin A4 | -0.0348271 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0339248 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0337311 |
| CCND1 | cyclin D1 | -0.033317 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.032983 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0328646 |
| MAP4 | microtubule-associated protein 4 | -0.0322743 |
| PKM | pyruvate kinase, muscle | -0.0318251 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0318053 |
| CYTH3 | cytohesin 3 | -0.0315568 |
| PTMA | prothymosin, alpha | -0.0310901 |
| TMSB4X | thymosin beta 4, X-linked | -0.0310502 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0308464 |
| SPAG9 | sperm associated antigen 9 | -0.0307419 |
| OGA | O-GlcNAcase | -0.0304309 |
| RIGI | RNA sensor RIG-I | -0.030231 |
| USP34 | ubiquitin specific peptidase 34 | -0.0288703 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0288 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0286107 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0284272 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0284015 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0280176 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0280126 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0270765 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0267935 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.026756 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0267354 |
| HLA-C | major histocompatibility complex, class I, C | -0.0265859 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0263616 |
| CENPF | centromere protein F, 350/400kDa | -0.0262225 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0261748 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0261304 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0260918 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | -0.026062 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0259689 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0258414 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0254192 |
| PGK1 | phosphoglycerate kinase 1 | -0.0252856 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0252295 |
| TNS3 | tensin 3 | -0.0252155 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0251088 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0249001 |
| TAGLN2 | transgelin 2 | -0.0248365 |
| MT2A | metallothionein 2A | -0.0248246 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0247782 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0246148 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0243786 |
| JAZF1 | JAZF zinc finger 1 | -0.0242913 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0236621 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0236 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0234177 |
