| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Docetaxel_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.161821 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.145155 |
| AREG | amphiregulin | 0.144387 |
| DST | dystonin | 0.142444 |
| RACK1 | receptor for activated C kinase 1 | 0.13565 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.128487 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.125839 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.119844 |
| TPI1 | triosephosphate isomerase 1 | 0.105842 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.101015 |
| NLGN1 | neuroligin 1 | 0.0972672 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0944918 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.092496 |
| ANXA1 | annexin A1 | 0.0910432 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0868052 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0833266 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0786293 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0699967 |
| LDHA | lactate dehydrogenase A | 0.0694385 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0649756 |
| RPS12 | ribosomal protein S12 | 0.0613834 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0610333 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0603191 |
| LMO7 | LIM domain 7 | 0.0595837 |
| TPM3 | tropomyosin 3 | 0.0571594 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0564852 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0561795 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0530114 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0527143 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0525372 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0510357 |
| RASAL2 | RAS protein activator like 2 | 0.0495855 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0493521 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0491763 |
| CLDN1 | claudin 1 | 0.0484097 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0473102 |
| DTNA | dystrobrevin, alpha | 0.0468583 |
| PCDH7 | protocadherin 7 | 0.0456657 |
| CALR | calreticulin | 0.0455637 |
| YAP1 | Yes-associated protein 1 | 0.0452711 |
| RPS2 | ribosomal protein S2 | 0.0442964 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0442282 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0438199 |
| ADIPOR2 | adiponectin receptor 2 | 0.0437911 |
| ENO1 | enolase 1, (alpha) | 0.0432558 |
| RPS3 | ribosomal protein S3 | 0.0428337 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0407246 |
| CCN2 | cellular communication network factor 2 | 0.0407188 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0406939 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0404336 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0400763 |
| ZNF804A | zinc finger protein 804A | 0.0395056 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0394984 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0381203 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0375183 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0371183 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0368286 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0366979 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0364114 |
| ERBIN | erbb2 interacting protein | 0.0361507 |
| TXNRD1 | thioredoxin reductase 1 | 0.0359347 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0358206 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0350238 |
| PDGFC | platelet derived growth factor C | 0.0348411 |
| MYPN | myopalladin | 0.0347972 |
| YBX3 | Y box binding protein 3 | 0.0338053 |
| RPS4X | ribosomal protein S4, X-linked | 0.0331533 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0329367 |
| HMGA2 | high mobility group AT-hook 2 | 0.0322396 |
| YBX1 | Y box binding protein 1 | 0.0315599 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0307544 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0305651 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0304249 |
| CCNL1 | cyclin L1 | 0.0299415 |
| EXOC6B | exocyst complex component 6B | 0.0294874 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0292846 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0291904 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.028942 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0287622 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0286701 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0285941 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0284661 |
| CLTC | clathrin, heavy chain (Hc) | 0.0275075 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.027475 |
| MTAP | methylthioadenosine phosphorylase | 0.0273313 |
| RPL26 | ribosomal protein L26 | 0.0271648 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0270614 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0266873 |
| TJP1 | tight junction protein 1 | 0.0264933 |
| RRM2 | ribonucleotide reductase M2 | 0.026372 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0261875 |
| RTN4 | reticulon 4 | 0.0261656 |
| PLK2 | polo-like kinase 2 | 0.0259511 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0258551 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0258161 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0255795 |
| PRDX1 | peroxiredoxin 1 | 0.025505 |
| PRR16 | proline rich 16 | 0.0252616 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0248798 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0248486 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.238482 |
| VIM | vimentin | -0.198277 |
| PTMA | prothymosin, alpha | -0.105707 |
| RPS6 | ribosomal protein S6 | -0.0772838 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0606949 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0606342 |
| MMP12 | matrix metallopeptidase 12 | -0.0600935 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0550811 |
| VMP1 | vacuole membrane protein 1 | -0.0550135 |
| TMSB10 | thymosin beta 10 | -0.0457923 |
| HMGA1 | high mobility group AT-hook 1 | -0.0426889 |
| RPS16 | ribosomal protein S16 | -0.0410075 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0399821 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0385035 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0380527 |
| CPOX | coproporphyrinogen oxidase | -0.0377641 |
| S100A6 | S100 calcium binding protein A6 | -0.0366694 |
| RPS19 | ribosomal protein S19 | -0.0346665 |
| SETD5 | SET domain containing 5 | -0.0338127 |
| RPL38 | ribosomal protein L38 | -0.0333251 |
| RPS23 | ribosomal protein S23 | -0.0329078 |
| RPL28 | ribosomal protein L28 | -0.0325482 |
| RPS21 | ribosomal protein S21 | -0.0315866 |
| PTMS | parathymosin | -0.0309465 |
| RPLP1 | ribosomal protein, large, P1 | -0.0302969 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0289089 |
| RPLP2 | ribosomal protein, large, P2 | -0.0287139 |
| RPS27 | ribosomal protein S27 | -0.0267603 |
| NHSL1 | NHS-like 1 | -0.026747 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0266715 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.026143 |
| RPS29 | ribosomal protein S29 | -0.0257708 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.0254218 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0250897 |
| RPS15 | ribosomal protein S15 | -0.0249054 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0248101 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0247806 |
| S100A10 | S100 calcium binding protein A10 | -0.0245177 |
| RPL36 | ribosomal protein L36 | -0.0232043 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0227977 |
| SESN2 | sestrin 2 | -0.0222482 |
| USP34 | ubiquitin specific peptidase 34 | -0.0220873 |
| RPL8 | ribosomal protein L8 | -0.0218529 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0218292 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0215286 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0214788 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0213293 |
| THOC1 | THO complex 1 | -0.0207171 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0200813 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0200761 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0200192 |
| RPL36A | ribosomal protein L36a | -0.019811 |
| RPS24 | ribosomal protein S24 | -0.0194923 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0192069 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0191564 |
| SYT1 | synaptotagmin I | -0.0190851 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0189939 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0186834 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0184356 |
| RPS25 | ribosomal protein S25 | -0.0184177 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | -0.0183533 |
| JMJD1C | jumonji domain containing 1C | -0.0180704 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -0.0180639 |
| H1-0 | H1.0 linker histone | -0.0180463 |
| VASP | vasodilator-stimulated phosphoprotein | -0.0180262 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0180082 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0179566 |
| TMEM123 | transmembrane protein 123 | -0.0178948 |
| ZFP64 | ZFP64 zinc finger protein | -0.0177056 |
| PARK7 | parkinson protein 7 | -0.0175509 |
| PFN1 | profilin 1 | -0.0175319 |
| RPL32 | ribosomal protein L32 | -0.0174044 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0171559 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0171245 |
| TNPO1 | transportin 1 | -0.0170642 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0167941 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.016742 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0167168 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0166626 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0165583 |
| PRR11 | proline rich 11 | -0.0163785 |
| HMGB1 | high mobility group box 1 | -0.0162709 |
| KLHL24 | kelch-like family member 24 | -0.0161919 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0161426 |
| ZFR | zinc finger RNA binding protein | -0.0161027 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0159944 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0158983 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0158857 |
| EIF4B | eukaryotic translation initiation factor 4B | -0.01575 |
| RPL21 | ribosomal protein L21 | -0.0156899 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0156382 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0156329 |
| RBM25 | RNA binding motif protein 25 | -0.0156016 |
| RPL34 | ribosomal protein L34 | -0.015598 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0155249 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0154932 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0154348 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0153449 |
| RSF1 | remodeling and spacing factor 1 | -0.0153188 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0151557 |
