| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.165667 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.11241 |
| MACC1 | metastasis associated in colon cancer 1 | 0.108368 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0786035 |
| ANXA2 | annexin A2 | 0.068725 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0685542 |
| TJP1 | tight junction protein 1 | 0.0644092 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0640712 |
| CCNL1 | cyclin L1 | 0.0638953 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0635582 |
| B2M | beta-2-microglobulin | 0.0622086 |
| MYO1E | myosin IE | 0.0620589 |
| EGR1 | early growth response 1 | 0.0582485 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0563964 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0553834 |
| AREG | amphiregulin | 0.0544823 |
| ERBIN | erbb2 interacting protein | 0.0535643 |
| EZR | ezrin | 0.0511241 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0502223 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0495196 |
| VMP1 | vacuole membrane protein 1 | 0.0482417 |
| INTS6 | integrator complex subunit 6 | 0.0479612 |
| RNF213 | ring finger protein 213 | 0.0475814 |
| JUN | jun proto-oncogene | 0.0473136 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0469241 |
| SMAD3 | SMAD family member 3 | 0.0464667 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0444193 |
| BCL2L1 | BCL2-like 1 | 0.0413424 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0410109 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0378695 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0378386 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.037828 |
| DSPP | dentin sialophosphoprotein | 0.0375464 |
| APOL1 | apolipoprotein L, 1 | 0.0373301 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0372422 |
| TRIM2 | tripartite motif containing 2 | 0.0364414 |
| DST | dystonin | 0.0362595 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0360168 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0354371 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0334953 |
| EFNB2 | ephrin-B2 | 0.0334819 |
| VEGFA | vascular endothelial growth factor A | 0.0326508 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0323819 |
| KYNU | kynureninase | 0.0319811 |
| SQSTM1 | sequestosome 1 | 0.0311241 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.030679 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0304808 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0304588 |
| VCL | vinculin | 0.0301249 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0294611 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0292272 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0285893 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0279326 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0276664 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0265264 |
| STK24 | serine/threonine kinase 24 | 0.0264031 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0263384 |
| ZNF292 | zinc finger protein 292 | 0.0258668 |
| XDH | xanthine dehydrogenase | 0.0258165 |
| MCL1 | myeloid cell leukemia 1 | 0.0256022 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.025139 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0250009 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0244754 |
| MYO5B | myosin VB | 0.024328 |
| LIPH | lipase, member H | 0.0242453 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0241714 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0240309 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0236986 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0236479 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.023504 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0233241 |
| MORF4L2 | mortality factor 4 like 2 | 0.0230694 |
| IRF1 | interferon regulatory factor 1 | 0.023009 |
| GOLGB1 | golgin B1 | 0.0229677 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0229354 |
| RND3 | Rho family GTPase 3 | 0.0227418 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0225631 |
| MLPH | melanophilin | 0.022402 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0221619 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0220167 |
| RBM47 | RNA binding motif protein 47 | 0.0219994 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0219432 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0218789 |
| DIAPH1 | diaphanous-related formin 1 | 0.0217852 |
| MX1 | MX dynamin-like GTPase 1 | 0.021732 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0216772 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.021375 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0211833 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0211358 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.020942 |
| IRS2 | insulin receptor substrate 2 | 0.0208952 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0208363 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0206195 |
| NDRG1 | N-myc downstream regulated 1 | 0.0204303 |
| UBAP1 | ubiquitin associated protein 1 | 0.0203291 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.019889 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0198035 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0197418 |
| DUSP10 | dual specificity phosphatase 10 | 0.0196958 |
| DUSP16 | dual specificity phosphatase 16 | 0.0196387 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.173354 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0931465 |
| HLA-B | major histocompatibility complex, class I, B | -0.0738845 |
| PTMA | prothymosin, alpha | -0.0727363 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0628477 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0626128 |
| LYZ | lysozyme | -0.0533947 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0458806 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0453871 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0439584 |
| RPS24 | ribosomal protein S24 | -0.0434932 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0434897 |
| XAF1 | XIAP associated factor 1 | -0.0431024 |
| RPS6 | ribosomal protein S6 | -0.0402949 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.039719 |
| RPL35A | ribosomal protein L35a | -0.039221 |
| NPSR1 | neuropeptide S receptor 1 | -0.0384518 |
| H1-0 | H1.0 linker histone | -0.0379257 |
| RPLP0 | ribosomal protein, large, P0 | -0.0375382 |
| RPLP1 | ribosomal protein, large, P1 | -0.0353517 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.034702 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0340461 |
| CANX | calnexin | -0.033831 |
| HLA-C | major histocompatibility complex, class I, C | -0.0326717 |
| RPL37 | ribosomal protein L37 | -0.031333 |
| RPL26 | ribosomal protein L26 | -0.0310241 |
| RNF43 | ring finger protein 43 | -0.030693 |
| RPL34 | ribosomal protein L34 | -0.0304598 |
| RPL19 | ribosomal protein L19 | -0.0298066 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.029386 |
| ASPH | aspartate beta-hydroxylase | -0.0290089 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0289772 |
| RPL11 | ribosomal protein L11 | -0.0287412 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0280223 |
| AHNAK | AHNAK nucleoprotein | -0.0279993 |
| AHI1 | Abelson helper integration site 1 | -0.0278488 |
| MT2A | metallothionein 2A | -0.0272595 |
| HMGB1 | high mobility group box 1 | -0.027164 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0266417 |
| ACTG1 | actin gamma 1 | -0.026429 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0261447 |
| RPL37A | ribosomal protein L37a | -0.0259485 |
| RPL7A | ribosomal protein L7a | -0.0256476 |
| MUC20 | mucin 20, cell surface associated | -0.0254438 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0253023 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0251119 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0248703 |
| RPS19 | ribosomal protein S19 | -0.0248553 |
| RPL12 | ribosomal protein L12 | -0.0247525 |
| PERP | PERP, TP53 apoptosis effector | -0.0247355 |
| RPL38 | ribosomal protein L38 | -0.0243746 |
| RPS25 | ribosomal protein S25 | -0.0243023 |
| RPS27A | ribosomal protein S27a | -0.0241986 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0241951 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0237817 |
| RPLP2 | ribosomal protein, large, P2 | -0.0237029 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0231687 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0231129 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.022731 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0226632 |
| TFRC | transferrin receptor | -0.0221816 |
| BRCA2 | breast cancer 2, early onset | -0.0221355 |
| GNAS | GNAS complex locus | -0.0220725 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0219877 |
| PHF3 | PHD finger protein 3 | -0.0219267 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0219251 |
| ARF1 | ADP-ribosylation factor 1 | -0.0217826 |
| RPL27A | ribosomal protein L27a | -0.0214348 |
| RPS8 | ribosomal protein S8 | -0.0212148 |
| CDCP1 | CUB domain containing protein 1 | -0.0211875 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0211165 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0209528 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0208889 |
| H3-3B | H3.3 histone B | -0.020779 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.0207228 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0205994 |
| FTL | ferritin, light polypeptide | -0.0200768 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0200294 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0200085 |
| RPL31 | ribosomal protein L31 | -0.019968 |
| RPL28 | ribosomal protein L28 | -0.0199551 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0198793 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0198749 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0197092 |
| RPS23 | ribosomal protein S23 | -0.0196735 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0195838 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0194757 |
| NF1 | neurofibromin 1 | -0.0194564 |
| RPS16 | ribosomal protein S16 | -0.0194065 |
| SP100 | SP100 nuclear antigen | -0.019279 |
| MT1X | metallothionein 1X | -0.0192394 |
| WDR45B | WD repeat domain 45B | -0.019159 |
| EPCAM | epithelial cell adhesion molecule | -0.0191239 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0189724 |
| TRIM56 | tripartite motif containing 56 | -0.0187394 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0186309 |
| RPL36A | ribosomal protein L36a | -0.0185212 |
| TXNIP | thioredoxin interacting protein | -0.0183304 |
| DIAPH3 | diaphanous-related formin 3 | -0.0181572 |
| GPX2 | glutathione peroxidase 2 | -0.0181141 |
