| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.398309 |
| NDRG1 | N-myc downstream regulated 1 | 0.259854 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.103336 |
| CDH13 | cadherin 13 | 0.0906567 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0906071 |
| VEGFA | vascular endothelial growth factor A | 0.0809262 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0742874 |
| CADM1 | cell adhesion molecule 1 | 0.0712224 |
| STC1 | stanniocalcin 1 | 0.0702571 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0621179 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0594962 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0575425 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.054483 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0508664 |
| B2M | beta-2-microglobulin | 0.0469131 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0448418 |
| RACK1 | receptor for activated C kinase 1 | 0.0447995 |
| MT2A | metallothionein 2A | 0.0441524 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0430505 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0426658 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.040911 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.039744 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0385682 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0370855 |
| ENO1 | enolase 1, (alpha) | 0.0344896 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0331509 |
| TUBB | tubulin, beta class I | 0.0316677 |
| FN1 | fibronectin 1 | 0.0316213 |
| INHBA | inhibin, beta A | 0.0313777 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0309863 |
| HDAC9 | histone deacetylase 9 | 0.0309854 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0309723 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0301546 |
| MYO10 | myosin X | 0.0288928 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0281326 |
| FNDC3B | fibronectin type III domain containing 3B | 0.027206 |
| PGM3 | phosphoglucomutase 3 | 0.0270254 |
| IL6ST | interleukin 6 signal transducer | 0.0263927 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0259475 |
| CALR | calreticulin | 0.0249942 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0248031 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0247758 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0246711 |
| FLNA | filamin A, alpha | 0.0243234 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0242113 |
| RUNX1 | runt-related transcription factor 1 | 0.0239807 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.023585 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0233165 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0230808 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0228307 |
| VCAN | versican | 0.0218683 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0217304 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0215931 |
| STC2 | stanniocalcin 2 | 0.0211514 |
| NEK10 | NIMA-related kinase 10 | 0.021045 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0210412 |
| MYO1B | myosin IB | 0.0209602 |
| FMNL2 | formin-like 2 | 0.0207559 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0204888 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0197472 |
| POTEF | POTE ankyrin domain family, member F | 0.0195967 |
| RPS12 | ribosomal protein S12 | 0.0193441 |
| TNS1 | tensin 1 | 0.0192729 |
| NOTCH2 | notch 2 | 0.0189053 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0189036 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0186895 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.0184709 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0184516 |
| NAV2 | neuron navigator 2 | 0.0184292 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0181168 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0180419 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0179922 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0179251 |
| NAV1 | neuron navigator 1 | 0.0177649 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0172169 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0171778 |
| RIGI | RNA sensor RIG-I | 0.0171593 |
| ATXN1 | ataxin 1 | 0.0170956 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.017074 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0170696 |
| SP100 | SP100 nuclear antigen | 0.0170303 |
| TPM3 | tropomyosin 3 | 0.0169699 |
| TPR | translocated promoter region, nuclear basket protein | 0.0167599 |
| SETBP1 | SET binding protein 1 | 0.0167563 |
| CLMP | CXADR-like membrane protein | 0.0167434 |
| HLA-A | major histocompatibility complex, class I, A | 0.0165003 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0164772 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0164386 |
| IL6 | interleukin 6 | 0.0159219 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0158226 |
| TPI1 | triosephosphate isomerase 1 | 0.0156245 |
| TUBA1C | tubulin, alpha 1c | 0.015606 |
| PRELID2 | PRELI domain containing 2 | 0.0151631 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0150628 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0149802 |
| UST | uronyl-2-sulfotransferase | 0.0148605 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.0145392 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0145099 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0144378 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0143923 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.184583 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.169639 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.1522 |
| VIM | vimentin | -0.119045 |
| COL1A2 | collagen, type I, alpha 2 | -0.0919791 |
| CD44 | CD44 molecule (Indian blood group) | -0.0737415 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0596654 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.053314 |
| MAP1B | microtubule-associated protein 1B | -0.0523064 |
| AHNAK | AHNAK nucleoprotein | -0.0522605 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0492865 |
| ATP13A3 | ATPase type 13A3 | -0.0457388 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0436286 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0415981 |
| LOX | lysyl oxidase | -0.0413193 |
| ANXA2 | annexin A2 | -0.0411375 |
| RRBP1 | ribosome binding protein 1 | -0.04069 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0394118 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.039157 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0370705 |
| SBF2 | SET binding factor 2 | -0.0365938 |
| PALLD | palladin, cytoskeletal associated protein | -0.0363175 |
| SPAG9 | sperm associated antigen 9 | -0.0345081 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0330748 |
| TPM4 | tropomyosin 4 | -0.0323201 |
| SQLE | squalene epoxidase | -0.0315931 |
| MAP4 | microtubule-associated protein 4 | -0.0308153 |
| PTMA | prothymosin, alpha | -0.0307229 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.030646 |
| NREP | neuronal regeneration related protein | -0.0304902 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0300625 |
| OSMR | oncostatin M receptor | -0.029921 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0298732 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.029334 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0289142 |
| LOXL2 | lysyl oxidase-like 2 | -0.0287401 |
| GOLGA4 | golgin A4 | -0.0285075 |
| KLF6 | Kruppel-like factor 6 | -0.0283036 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0277644 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0276675 |
| RASA2 | RAS p21 protein activator 2 | -0.0269667 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0268048 |
| CAVIN1 | caveolae associated protein 1 | -0.026645 |
| TMSB10 | thymosin beta 10 | -0.0261526 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0248776 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0244619 |
| ICAM1 | intercellular adhesion molecule 1 | -0.023555 |
| FBN1 | fibrillin 1 | -0.0234586 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0233731 |
| HDLBP | high density lipoprotein binding protein | -0.0233175 |
| COG5 | component of oligomeric golgi complex 5 | -0.0224397 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0221828 |
| ACTN4 | actinin, alpha 4 | -0.0221029 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0218766 |
| CANX | calnexin | -0.0218547 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.021715 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0215255 |
| FRMD4A | FERM domain containing 4A | -0.0212724 |
| EVI5 | ecotropic viral integration site 5 | -0.020811 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0205358 |
| H1-0 | H1.0 linker histone | -0.020447 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.020242 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0198059 |
| JMJD1C | jumonji domain containing 1C | -0.0197768 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0197313 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0197255 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0194308 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0191986 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0190821 |
| NF1 | neurofibromin 1 | -0.0189359 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0186637 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0185319 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0184897 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0181062 |
| PXDN | peroxidasin | -0.0180885 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.0180453 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0179841 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0179263 |
| TMEM263 | transmembrane protein 263 | -0.0178182 |
| TMEM39A | transmembrane protein 39A | -0.017717 |
| SDC2 | syndecan 2 | -0.0173031 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0172384 |
| RTN4 | reticulon 4 | -0.0172257 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0170481 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0168064 |
| S100A6 | S100 calcium binding protein A6 | -0.01659 |
| TPM1 | tropomyosin 1 (alpha) | -0.0162834 |
| ABLIM3 | actin binding LIM protein family, member 3 | -0.0162131 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | -0.0160892 |
| EHBP1 | EH domain binding protein 1 | -0.0160518 |
| RASAL2 | RAS protein activator like 2 | -0.0159304 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0158959 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0156069 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0155283 |
| LMNA | lamin A/C | -0.015512 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0154393 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0152768 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0152307 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0151509 |
| RNF121 | ring finger protein 121 | -0.0150854 |
