| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.309813 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.112208 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0615064 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0593632 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0573285 |
| ATXN1 | ataxin 1 | 0.0550028 |
| PDLIM5 | PDZ and LIM domain 5 | 0.052991 |
| INTS6 | integrator complex subunit 6 | 0.0497879 |
| FAM107B | family with sequence similarity 107, member B | 0.0494948 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0428487 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0352033 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0332123 |
| ASPH | aspartate beta-hydroxylase | 0.0317113 |
| RNF213 | ring finger protein 213 | 0.0293689 |
| GPC6 | glypican 6 | 0.0291411 |
| VCL | vinculin | 0.028757 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0285375 |
| DST | dystonin | 0.028442 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0280061 |
| FRMD5 | FERM domain containing 5 | 0.0279582 |
| ITGAV | integrin, alpha V | 0.027826 |
| GK | glycerol kinase | 0.027456 |
| SMAD3 | SMAD family member 3 | 0.0265955 |
| VMP1 | vacuole membrane protein 1 | 0.0261101 |
| HPCAL1 | hippocalcin-like 1 | 0.0260338 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0259422 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0250561 |
| RIGI | RNA sensor RIG-I | 0.025024 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0244505 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0236553 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0232113 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0229052 |
| TLE4 | transducin-like enhancer of split 4 | 0.0228575 |
| NABP1 | nucleic acid binding protein 1 | 0.0228546 |
| MYO1E | myosin IE | 0.0221215 |
| FILIP1L | filamin A interacting protein 1-like | 0.0212823 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.021038 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0204467 |
| KYNU | kynureninase | 0.019862 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0197374 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0194399 |
| RAD51B | RAD51 paralog B | 0.0191468 |
| ZNF644 | zinc finger protein 644 | 0.0190514 |
| FLNA | filamin A, alpha | 0.0189686 |
| MYO5B | myosin VB | 0.0188913 |
| PALLD | palladin, cytoskeletal associated protein | 0.0187838 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0186687 |
| SP100 | SP100 nuclear antigen | 0.0182979 |
| FAT1 | FAT atypical cadherin 1 | 0.0181803 |
| FMNL2 | formin-like 2 | 0.0175244 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0174639 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0173947 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.0170673 |
| SERTAD2 | SERTA domain containing 2 | 0.0170383 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.016958 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0167855 |
| RASA2 | RAS p21 protein activator 2 | 0.016626 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0166123 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.016392 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0163908 |
| VCAN | versican | 0.0162377 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0161931 |
| DIAPH1 | diaphanous-related formin 1 | 0.0161302 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0160505 |
| UBAP2 | ubiquitin associated protein 2 | 0.0160172 |
| FERMT2 | fermitin family member 2 | 0.0158329 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0155207 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0154803 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.015452 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.0153813 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0150199 |
| HDAC4 | histone deacetylase 4 | 0.0147522 |
| PRKCA | protein kinase C, alpha | 0.0147232 |
| FOXP1 | forkhead box P1 | 0.0145848 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0144536 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0140643 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 0.0139525 |
| RSU1 | Ras suppressor protein 1 | 0.0139487 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0139331 |
| LMO7 | LIM domain 7 | 0.0139038 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0135282 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0134422 |
| FLNB | filamin B, beta | 0.0134042 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.013312 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0131899 |
| TPM1 | tropomyosin 1 (alpha) | 0.0130939 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0128416 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0128326 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0127864 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0127802 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.012763 |
| HOMER1 | homer scaffolding protein 1 | 0.012716 |
| SVIL | supervillin | 0.0126101 |
| JAG1 | jagged 1 | 0.0125768 |
| MCL1 | myeloid cell leukemia 1 | 0.0125202 |
| PRELID2 | PRELI domain containing 2 | 0.0124306 |
| ANXA3 | annexin A3 | 0.0124263 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0124253 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0122567 |
| PLXDC2 | plexin domain containing 2 | 0.012201 |
| Symbol | Name | Standardized Value |
|---|---|---|
| APOB | apolipoprotein B | -0.170036 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.162058 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.158978 |
| GPC3 | glypican 3 | -0.106193 |
| MT2A | metallothionein 2A | -0.0993515 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0981198 |
| FN1 | fibronectin 1 | -0.0939254 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0920839 |
| RPS6 | ribosomal protein S6 | -0.0885437 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0868275 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0775921 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0762106 |
| APOA2 | apolipoprotein A-II | -0.0742746 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0724808 |
| TRIM26 | tripartite motif containing 26 | -0.0683381 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0607336 |
| ENO1 | enolase 1, (alpha) | -0.0605343 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0595234 |
| PEG3 | paternally expressed 3 | -0.0545165 |
| RPLP1 | ribosomal protein, large, P1 | -0.0544096 |
| RRBP1 | ribosome binding protein 1 | -0.0524777 |
| A2M | alpha-2-macroglobulin | -0.051966 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0508854 |
| RPS19 | ribosomal protein S19 | -0.0505963 |
| AHSG | alpha-2-HS-glycoprotein | -0.0498028 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0496471 |
| FTL | ferritin, light polypeptide | -0.0495761 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0476052 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0468139 |
| RPL11 | ribosomal protein L11 | -0.0458734 |
| APOE | apolipoprotein E | -0.0452238 |
| TF | transferrin | -0.0452165 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0438475 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0438292 |
| RPL35A | ribosomal protein L35a | -0.0437488 |
| RPL34 | ribosomal protein L34 | -0.0431257 |
| RPS24 | ribosomal protein S24 | -0.0429743 |
| RPL23 | ribosomal protein L23 | -0.0421995 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0420688 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0412935 |
| RPS8 | ribosomal protein S8 | -0.041098 |
| TMEM123 | transmembrane protein 123 | -0.0407349 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0402756 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0395737 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0386787 |
| RBM39 | RNA binding motif protein 39 | -0.0384454 |
| RPL31 | ribosomal protein L31 | -0.0384393 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0383629 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0379392 |
| CP | ceruloplasmin (ferroxidase) | -0.0367116 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0366552 |
| RPS12 | ribosomal protein S12 | -0.0362446 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0358965 |
| TMSB10 | thymosin beta 10 | -0.035741 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0353457 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0352411 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0350262 |
| RPS27A | ribosomal protein S27a | -0.0349231 |
| CFB | complement factor B | -0.0341158 |
| RPL5 | ribosomal protein L5 | -0.0331765 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.032986 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0313888 |
| C3 | complement component 3 | -0.0313558 |
| CANX | calnexin | -0.0313263 |
| RPL37A | ribosomal protein L37a | -0.0312038 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0309812 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0304651 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0302038 |
| SDC4 | syndecan 4 | -0.0301376 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0300531 |
| APOA1 | apolipoprotein A-I | -0.0299531 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0298869 |
| RPL19 | ribosomal protein L19 | -0.029782 |
| JMJD1C | jumonji domain containing 1C | -0.0296631 |
| RPS29 | ribosomal protein S29 | -0.0293781 |
| PTMA | prothymosin, alpha | -0.0292482 |
| RPL12 | ribosomal protein L12 | -0.0283876 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0279422 |
| RPL26 | ribosomal protein L26 | -0.0278737 |
| RPLP2 | ribosomal protein, large, P2 | -0.0277359 |
| H1-0 | H1.0 linker histone | -0.0275859 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0275228 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0273041 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0270162 |
| SELENOP | selenoprotein P | -0.0269858 |
| S100A9 | S100 calcium binding protein A9 | -0.0266699 |
| CPE | carboxypeptidase E | -0.0265561 |
| WDR45B | WD repeat domain 45B | -0.0262727 |
| MATR3 | matrin 3 | -0.0260821 |
| CALR | calreticulin | -0.0260412 |
| RPS23 | ribosomal protein S23 | -0.0260192 |
| GNAS | GNAS complex locus | -0.0258618 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0258038 |
| RPLP0 | ribosomal protein, large, P0 | -0.0257833 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0254624 |
| RPS21 | ribosomal protein S21 | -0.0251755 |
| PGK1 | phosphoglycerate kinase 1 | -0.0250131 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0248971 |
| UBC | ubiquitin C | -0.0245288 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0236778 |
