| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0483131 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0466828 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0420944 |
| INTS6 | integrator complex subunit 6 | 0.0411192 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0404492 |
| DOK5 | docking protein 5 | 0.0395707 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.03795 |
| SMAD3 | SMAD family member 3 | 0.036588 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0351194 |
| AOPEP | aminopeptidase O (putative) | 0.0320681 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0313648 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0308473 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0295319 |
| PRELID2 | PRELI domain containing 2 | 0.028998 |
| MYOF | myoferlin | 0.0287414 |
| LAMA5 | laminin, alpha 5 | 0.0287168 |
| LMO7 | LIM domain 7 | 0.0282392 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0279972 |
| EFNA5 | ephrin-A5 | 0.0267875 |
| HMGA2 | high mobility group AT-hook 2 | 0.0266329 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0262853 |
| ASPH | aspartate beta-hydroxylase | 0.0260592 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0259816 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0258102 |
| SMYD3 | SET and MYND domain containing 3 | 0.0253342 |
| PLEC | plectin | 0.0250722 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.024313 |
| RAD51B | RAD51 paralog B | 0.0243078 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0242533 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0240336 |
| FOXP1 | forkhead box P1 | 0.0232489 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0231991 |
| DST | dystonin | 0.0228513 |
| PTK2 | protein tyrosine kinase 2 | 0.0227033 |
| VCL | vinculin | 0.0224585 |
| ATXN1 | ataxin 1 | 0.0223559 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0217779 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0217608 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0216282 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0216165 |
| MSN | moesin | 0.0214191 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0213652 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0211578 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0211216 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0203574 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0198915 |
| CTBP2 | C-terminal binding protein 2 | 0.0193716 |
| JAG1 | jagged 1 | 0.0182145 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0179303 |
| SETBP1 | SET binding protein 1 | 0.0179297 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0179187 |
| ACTN1 | actinin, alpha 1 | 0.0179088 |
| FRMD6 | FERM domain containing 6 | 0.0177779 |
| FMNL2 | formin-like 2 | 0.0177581 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0177004 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0175577 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0174297 |
| RNF217 | ring finger protein 217 | 0.017284 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0170114 |
| CDK17 | cyclin-dependent kinase 17 | 0.0168892 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0166308 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0165093 |
| FLNA | filamin A, alpha | 0.0164931 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0163826 |
| PLS3 | plastin 3 | 0.0162991 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.016023 |
| MEF2A | myocyte enhancer factor 2A | 0.015995 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0159254 |
| CMIP | c-Maf inducing protein | 0.0157057 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0155747 |
| BARX2 | BARX homeobox 2 | 0.0154219 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0154072 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0153721 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0152544 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0151749 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0150892 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0149847 |
| AMOTL1 | angiomotin like 1 | 0.0148873 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0145675 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0145356 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.014367 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0140113 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0137606 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0134956 |
| RASAL2 | RAS protein activator like 2 | 0.0133665 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0132938 |
| BCR | breakpoint cluster region | 0.0130633 |
| MED13L | mediator complex subunit 13-like | 0.0129576 |
| EXOC4 | exocyst complex component 4 | 0.0129539 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0128363 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0127378 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0126802 |
| TENM4 | teneurin transmembrane protein 4 | 0.0126683 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0126658 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0126179 |
| SULF2 | sulfatase 2 | 0.0126071 |
| KIAA1217 | KIAA1217 | 0.0124934 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.012256 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0122015 |
| NECTIN1 | nectin cell adhesion molecule 1 | 0.0121651 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.227758 |
| B2M | beta-2-microglobulin | -0.107785 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0992196 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0893146 |
| PTMA | prothymosin, alpha | -0.0876091 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0845959 |
| TMSB10 | thymosin beta 10 | -0.0811846 |
| FLNB | filamin B, beta | -0.0757213 |
| TMSB4X | thymosin beta 4, X-linked | -0.0702291 |
| ENO1 | enolase 1, (alpha) | -0.0633953 |
| LDHA | lactate dehydrogenase A | -0.0596475 |
| PGK1 | phosphoglycerate kinase 1 | -0.0593986 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0592181 |
| CLU | clusterin | -0.0590293 |
| NDRG1 | N-myc downstream regulated 1 | -0.0584846 |
| MT2A | metallothionein 2A | -0.0584281 |
| RPS21 | ribosomal protein S21 | -0.0584037 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0576188 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0552794 |
| RPS8 | ribosomal protein S8 | -0.0545723 |
| EMP1 | epithelial membrane protein 1 | -0.0540444 |
| SULF1 | sulfatase 1 | -0.0516849 |
| S100A10 | S100 calcium binding protein A10 | -0.0512982 |
| HLA-B | major histocompatibility complex, class I, B | -0.0501616 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0481211 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0460122 |
| RPS6 | ribosomal protein S6 | -0.0458269 |
| RPS3 | ribosomal protein S3 | -0.0452935 |
| CANX | calnexin | -0.0400442 |
| LMNA | lamin A/C | -0.0397101 |
| GOLGA4 | golgin A4 | -0.0397079 |
| RPLP1 | ribosomal protein, large, P1 | -0.0394141 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0388728 |
| RPL11 | ribosomal protein L11 | -0.0381862 |
| GNAS | GNAS complex locus | -0.0375949 |
| FTL | ferritin, light polypeptide | -0.0375898 |
| KRT17 | keratin 17, type I | -0.0367685 |
| RPS13 | ribosomal protein S13 | -0.0361005 |
| IGF2 | insulin-like growth factor 2 | -0.0359396 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0358861 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0358094 |
| RACK1 | receptor for activated C kinase 1 | -0.0357016 |
| HM13 | histocompatibility (minor) 13 | -0.0354022 |
| HLA-E | major histocompatibility complex, class I, E | -0.0353161 |
| EZR | ezrin | -0.0351497 |
| RPL12 | ribosomal protein L12 | -0.0346997 |
| PODXL | podocalyxin-like | -0.0343135 |
| S100A6 | S100 calcium binding protein A6 | -0.0336452 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0336104 |
| CALU | calumenin | -0.0334209 |
| RPLP2 | ribosomal protein, large, P2 | -0.0333455 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0325065 |
| RPS12 | ribosomal protein S12 | -0.0323102 |
| RPS19 | ribosomal protein S19 | -0.032233 |
| S100A11 | S100 calcium binding protein A11 | -0.031286 |
| ANXA2 | annexin A2 | -0.0311274 |
| RPL35A | ribosomal protein L35a | -0.0300964 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0295504 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0291559 |
| RPS25 | ribosomal protein S25 | -0.0288904 |
| RPL37 | ribosomal protein L37 | -0.0286221 |
| RPL34 | ribosomal protein L34 | -0.0279273 |
| S100A9 | S100 calcium binding protein A9 | -0.027852 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0277852 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0276481 |
| SQLE | squalene epoxidase | -0.0276175 |
| CD44 | CD44 molecule (Indian blood group) | -0.0275872 |
| CALR | calreticulin | -0.0272441 |
| MORF4L2 | mortality factor 4 like 2 | -0.0272001 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.027018 |
| RPL37A | ribosomal protein L37a | -0.0266999 |
| RPLP0 | ribosomal protein, large, P0 | -0.0259869 |
| RPS24 | ribosomal protein S24 | -0.0259348 |
| RPL26 | ribosomal protein L26 | -0.0255281 |
| AHNAK | AHNAK nucleoprotein | -0.0255026 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0254691 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0254075 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0253945 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0251253 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0251087 |
| RPL31 | ribosomal protein L31 | -0.0249088 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0249046 |
| H1-0 | H1.0 linker histone | -0.0246483 |
| WASF2 | WAS protein family, member 2 | -0.0245574 |
| CD9 | CD9 molecule | -0.0244348 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0244166 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0243927 |
| CAVIN1 | caveolae associated protein 1 | -0.0241459 |
| HLA-A | major histocompatibility complex, class I, A | -0.024118 |
| RAI14 | retinoic acid induced 14 | -0.0241151 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0239711 |
| RPL19 | ribosomal protein L19 | -0.0239624 |
| RPS27A | ribosomal protein S27a | -0.0238157 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0236591 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0236563 |
| PKM | pyruvate kinase, muscle | -0.0235403 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.023507 |
| DSTN | destrin (actin depolymerizing factor) | -0.0232596 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0231821 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.023169 |