| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Docetaxel_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.134528 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.101188 |
| AREG | amphiregulin | 0.082573 |
| FAT1 | FAT atypical cadherin 1 | 0.0782205 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0766604 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0686745 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0669122 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0656898 |
| MYO1E | myosin IE | 0.0627594 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0584762 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0580271 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0552557 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0524357 |
| VCL | vinculin | 0.0503189 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0499192 |
| LDHA | lactate dehydrogenase A | 0.0486468 |
| RNF145 | ring finger protein 145 | 0.0477707 |
| VMP1 | vacuole membrane protein 1 | 0.0477209 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.046814 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0462137 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0458562 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0456781 |
| ITGA6 | integrin, alpha 6 | 0.0443369 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0426625 |
| ONECUT3 | one cut homeobox 3 | 0.0424757 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0424255 |
| TRIM2 | tripartite motif containing 2 | 0.0419768 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0419693 |
| CENPF | centromere protein F, 350/400kDa | 0.0418952 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0413235 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0403322 |
| VEGFA | vascular endothelial growth factor A | 0.0396199 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0392898 |
| RPL23 | ribosomal protein L23 | 0.0387432 |
| TPM3 | tropomyosin 3 | 0.0383607 |
| RACK1 | receptor for activated C kinase 1 | 0.0371541 |
| CTBP2 | C-terminal binding protein 2 | 0.0371073 |
| RPL3 | ribosomal protein L3 | 0.0368638 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0367081 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0363195 |
| CD44 | CD44 molecule (Indian blood group) | 0.0361957 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0361692 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0352326 |
| LMO7 | LIM domain 7 | 0.0350906 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0343353 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0339547 |
| MUC13 | mucin 13, cell surface associated | 0.033847 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0338181 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0330619 |
| TXNIP | thioredoxin interacting protein | 0.0328694 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0315346 |
| MYO5B | myosin VB | 0.0314141 |
| RNF43 | ring finger protein 43 | 0.0313268 |
| MED13L | mediator complex subunit 13-like | 0.0312924 |
| DSPP | dentin sialophosphoprotein | 0.0308484 |
| MED13 | mediator complex subunit 13 | 0.0306638 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0302271 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0294146 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0291303 |
| SMAD2 | SMAD family member 2 | 0.0289315 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0285942 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0285319 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0283633 |
| USP53 | ubiquitin specific peptidase 53 | 0.0278664 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0276596 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.027647 |
| USP6NL | USP6 N-terminal like | 0.0274131 |
| CCNL1 | cyclin L1 | 0.027167 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0270293 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0269725 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0266648 |
| B2M | beta-2-microglobulin | 0.02654 |
| INTS6 | integrator complex subunit 6 | 0.0262013 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0260296 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0260203 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0259226 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0258649 |
| NRXN3 | neurexin 3 | 0.0258449 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0258415 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0258177 |
| NEBL | nebulette | 0.0256643 |
| TPI1 | triosephosphate isomerase 1 | 0.0255518 |
| SIK3 | SIK family kinase 3 | 0.0254424 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0251424 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0250617 |
| PDZD8 | PDZ domain containing 8 | 0.0242727 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0242366 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.023931 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0237412 |
| RPS3 | ribosomal protein S3 | 0.0234561 |
| PLS1 | plastin 1 | 0.0233279 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0232067 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.023167 |
| RYBP | RING1 and YY1 binding protein | 0.0230506 |
| PCBP2 | poly(rC) binding protein 2 | 0.0225619 |
| FOXP1 | forkhead box P1 | 0.022538 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0224554 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0221326 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0219505 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0218038 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.214544 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.153415 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.146772 |
| PTMA | prothymosin, alpha | -0.126422 |
| FLNB | filamin B, beta | -0.0936803 |
| RPS6 | ribosomal protein S6 | -0.076857 |
| ANXA2 | annexin A2 | -0.0711044 |
| S100A6 | S100 calcium binding protein A6 | -0.0638739 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0633585 |
| AHNAK | AHNAK nucleoprotein | -0.0631633 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.062708 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0570325 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0557849 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0545662 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0534589 |
| TPM4 | tropomyosin 4 | -0.0518914 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0506635 |
| ACTG1 | actin gamma 1 | -0.0495351 |
| RPLP1 | ribosomal protein, large, P1 | -0.0481787 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0478541 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0477221 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0460561 |
| CCND1 | cyclin D1 | -0.0455427 |
| MUC17 | mucin 17, cell surface associated | -0.0447959 |
| RPS24 | ribosomal protein S24 | -0.0443506 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0426254 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.041847 |
| RNF217 | ring finger protein 217 | -0.0416355 |
| RIN2 | Ras and Rab interactor 2 | -0.0404414 |
| AGR2 | anterior gradient 2 | -0.0402617 |
| FERMT1 | fermitin family member 1 | -0.0398999 |
| EZR | ezrin | -0.0395567 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0391484 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0379803 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0376611 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0372241 |
| ITGB4 | integrin, beta 4 | -0.0371471 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0359995 |
| PRSS3 | protease, serine, 3 | -0.0353997 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0346841 |
| KLK10 | kallikrein-related peptidase 10 | -0.0334713 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0330898 |
| PIGR | polymeric immunoglobulin receptor | -0.0330292 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0325379 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0320325 |
| RPL7A | ribosomal protein L7a | -0.0309523 |
| TMSB10 | thymosin beta 10 | -0.0309231 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0307536 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0307047 |
| CALB1 | calbindin 1, 28kDa | -0.0305003 |
| RPLP0 | ribosomal protein, large, P0 | -0.0304994 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.03047 |
| EHBP1 | EH domain binding protein 1 | -0.0304567 |
| CANX | calnexin | -0.0303645 |
| NFIA | nuclear factor I/A | -0.0298854 |
| ZNF33A | zinc finger protein 33A | -0.0276979 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0273347 |
| IER3 | immediate early response 3 | -0.0271279 |
| HDLBP | high density lipoprotein binding protein | -0.0266282 |
| HMGB1 | high mobility group box 1 | -0.02653 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.025819 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0255592 |
| SBF2 | SET binding factor 2 | -0.0254012 |
| RPL37 | ribosomal protein L37 | -0.0253927 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0251016 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0249341 |
| FRMD5 | FERM domain containing 5 | -0.0247012 |
| EPCAM | epithelial cell adhesion molecule | -0.0245797 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.024467 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0238924 |
| RPS16 | ribosomal protein S16 | -0.023887 |
| PLCB4 | phospholipase C, beta 4 | -0.0237497 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0237464 |
| DSG2 | desmoglein 2 | -0.023575 |
| SH3D19 | SH3 domain containing 19 | -0.0235688 |
| RPL38 | ribosomal protein L38 | -0.0234626 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0233151 |
| DEK | DEK proto-oncogene | -0.023277 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0231066 |
| CDK13 | cyclin-dependent kinase 13 | -0.0230316 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0229583 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0228107 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0227813 |
| KRT8 | keratin 8, type II | -0.0222581 |
| HDAC2 | histone deacetylase 2 | -0.0222051 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0221051 |
| RPS27A | ribosomal protein S27a | -0.0221017 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0221014 |
| TFF1 | trefoil factor 1 | -0.0218346 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0218112 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0218108 |
| AHI1 | Abelson helper integration site 1 | -0.0218099 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0217101 |
| RPL13A | ribosomal protein L13a | -0.0215183 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0212949 |
| RPL34 | ribosomal protein L34 | -0.0212346 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0211696 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0209519 |
| RRBP1 | ribosome binding protein 1 | -0.0207351 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0206845 |
