| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Docetaxel_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.169979 |
| TP63 | tumor protein p63 | 0.14789 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.106658 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0952633 |
| HLA-B | major histocompatibility complex, class I, B | 0.0773533 |
| CAPRIN2 | caprin family member 2 | 0.0712622 |
| RACK1 | receptor for activated C kinase 1 | 0.0707164 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0659147 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0644881 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0642457 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0599788 |
| B2M | beta-2-microglobulin | 0.0561209 |
| RNF213 | ring finger protein 213 | 0.0560975 |
| SP100 | SP100 nuclear antigen | 0.0538905 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0526771 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0501576 |
| RAD51B | RAD51 paralog B | 0.049936 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0492273 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0491143 |
| HLA-A | major histocompatibility complex, class I, A | 0.0485396 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0466105 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0442187 |
| RPS12 | ribosomal protein S12 | 0.043458 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0428451 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0414679 |
| VCL | vinculin | 0.0391646 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0381721 |
| CADM2 | cell adhesion molecule 2 | 0.0370359 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0338619 |
| ENO1 | enolase 1, (alpha) | 0.0335148 |
| RTTN | rotatin | 0.0328599 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0312721 |
| PDE10A | phosphodiesterase 10A | 0.0306411 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0305802 |
| TPI1 | triosephosphate isomerase 1 | 0.0303489 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0303249 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0301604 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0298895 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0298592 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0298569 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0295128 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0292298 |
| EXOC4 | exocyst complex component 4 | 0.0290774 |
| TUBA1B | tubulin, alpha 1b | 0.0287389 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0286618 |
| CDK6 | cyclin-dependent kinase 6 | 0.0285871 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0278884 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0278372 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.027431 |
| FERMT1 | fermitin family member 1 | 0.0273382 |
| SQSTM1 | sequestosome 1 | 0.0273007 |
| SDC4 | syndecan 4 | 0.027238 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0271213 |
| FOXP1 | forkhead box P1 | 0.0271018 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0267341 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0267273 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0266106 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0262685 |
| RUNX1 | runt-related transcription factor 1 | 0.0259175 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0258775 |
| RPL37 | ribosomal protein L37 | 0.0257096 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0255813 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0255609 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0252272 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0249188 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.024855 |
| CBX3 | chromobox homolog 3 | 0.0247996 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0246372 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.0243335 |
| RRM2 | ribonucleotide reductase M2 | 0.0242177 |
| TUBB | tubulin, beta class I | 0.0241104 |
| TPRG1 | tumor protein p63 regulated 1 | 0.0238036 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0231176 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0230564 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0229268 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0228621 |
| INTS6 | integrator complex subunit 6 | 0.0228077 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0227912 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0227007 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0226774 |
| TPM3 | tropomyosin 3 | 0.0223528 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0222643 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0220732 |
| CCNL1 | cyclin L1 | 0.0220216 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0218503 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0216825 |
| CEP128 | centrosomal protein 128kDa | 0.0216146 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0213793 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0210713 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0210632 |
| TGM2 | transglutaminase 2 | 0.0210547 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0210499 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0208487 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0206045 |
| HLA-E | major histocompatibility complex, class I, E | 0.0204739 |
| DNER | delta/notch-like EGF repeat containing | 0.0204363 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0202947 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0201261 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0196376 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0196372 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.324813 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.154955 |
| VIM | vimentin | -0.14031 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.118918 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0994303 |
| TXNRD1 | thioredoxin reductase 1 | -0.0821474 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0760003 |
| EZR | ezrin | -0.0670157 |
| RPS6 | ribosomal protein S6 | -0.062338 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0570283 |
| AHNAK | AHNAK nucleoprotein | -0.0556695 |
| MYOF | myoferlin | -0.0542097 |
| CANX | calnexin | -0.0509816 |
| RAI1 | retinoic acid induced 1 | -0.0464173 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0449785 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0448514 |
| RTN4 | reticulon 4 | -0.0429368 |
| TMSB10 | thymosin beta 10 | -0.0427301 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.040285 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0363244 |
| HDLBP | high density lipoprotein binding protein | -0.0359533 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0358885 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0354502 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0353854 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0350959 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.034867 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0340074 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0326966 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0312136 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0310289 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0301554 |
| RPLP1 | ribosomal protein, large, P1 | -0.0300577 |
| TMEM123 | transmembrane protein 123 | -0.0299675 |
| USP34 | ubiquitin specific peptidase 34 | -0.0297487 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0295734 |
| LOXL2 | lysyl oxidase-like 2 | -0.0295503 |
| ACTG1 | actin gamma 1 | -0.0295128 |
| YEATS2 | YEATS domain containing 2 | -0.0290994 |
| GOLGA4 | golgin A4 | -0.0286686 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0275543 |
| ZNF217 | zinc finger protein 217 | -0.0275136 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0274405 |
| SBF2 | SET binding factor 2 | -0.0274323 |
| ZNF292 | zinc finger protein 292 | -0.0269705 |
| ANXA1 | annexin A1 | -0.0268987 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.026898 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0265261 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0260425 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0260127 |
| FLNB | filamin B, beta | -0.0258412 |
| TMEM41B | transmembrane protein 41B | -0.0257017 |
| DOCK11 | dedicator of cytokinesis 11 | -0.025696 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0253611 |
| RPS23 | ribosomal protein S23 | -0.0253 |
| TXNIP | thioredoxin interacting protein | -0.0252258 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0251414 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0247296 |
| WASF2 | WAS protein family, member 2 | -0.0243103 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0236614 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0235823 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0232018 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0231405 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.022674 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0225608 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0225419 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0225089 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0221963 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.022159 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0220166 |
| S100A10 | S100 calcium binding protein A10 | -0.0214233 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0213847 |
| RPS29 | ribosomal protein S29 | -0.0213372 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0213039 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0212361 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0212211 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0211819 |
| RPL5 | ribosomal protein L5 | -0.0210523 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0209336 |
| POM121 | POM121 transmembrane nucleoporin | -0.0208928 |
| APP | amyloid beta (A4) precursor protein | -0.0206687 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0203699 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0203481 |
| EMP1 | epithelial membrane protein 1 | -0.0202788 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0202217 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0201601 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0200339 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0199943 |
| JMJD1C | jumonji domain containing 1C | -0.0199855 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0199492 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0198917 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0198134 |
| SPAG9 | sperm associated antigen 9 | -0.0196605 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0196421 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0195745 |
| UPP1 | uridine phosphorylase 1 | -0.0195438 |
| ANXA2 | annexin A2 | -0.0194066 |
| MORF4L2 | mortality factor 4 like 2 | -0.0193624 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0189356 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0188829 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.018861 |
