| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.128805 |
| MT2A | metallothionein 2A | 0.0793452 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0783092 |
| TXNRD1 | thioredoxin reductase 1 | 0.0764126 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0729256 |
| ENO1 | enolase 1, (alpha) | 0.0665676 |
| GRAMD1B | GRAM domain containing 1B | 0.0635241 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0602774 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0576833 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.05534 |
| SLTM | SAFB-like, transcription modulator | 0.0542693 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0521101 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0513364 |
| PLEC | plectin | 0.050779 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0501294 |
| RACK1 | receptor for activated C kinase 1 | 0.0498967 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0487554 |
| LAMB3 | laminin, beta 3 | 0.0477858 |
| SPAG9 | sperm associated antigen 9 | 0.0475529 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0474638 |
| PM20D1 | peptidase M20 domain containing 1 | 0.043793 |
| MKI67 | marker of proliferation Ki-67 | 0.0427378 |
| GOLGB1 | golgin B1 | 0.0422164 |
| RPS3 | ribosomal protein S3 | 0.0420894 |
| TOP1 | topoisomerase (DNA) I | 0.0419293 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0399412 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0396714 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0375976 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0368668 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0363817 |
| HYOU1 | hypoxia up-regulated 1 | 0.0362516 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0352303 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0340804 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0339241 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0336736 |
| DSPP | dentin sialophosphoprotein | 0.033612 |
| LAMA4 | laminin, alpha 4 | 0.0335081 |
| TPI1 | triosephosphate isomerase 1 | 0.0331518 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0331374 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0315991 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0313536 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0311742 |
| MORF4L2 | mortality factor 4 like 2 | 0.0309788 |
| ATP11A | ATPase, class VI, type 11A | 0.0307188 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0302087 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0289494 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0288019 |
| MCL1 | myeloid cell leukemia 1 | 0.0283862 |
| EZR | ezrin | 0.0278279 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0273269 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0269452 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.026608 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.026574 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0264503 |
| LDHA | lactate dehydrogenase A | 0.026219 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0260529 |
| HDLBP | high density lipoprotein binding protein | 0.0260187 |
| PYGL | phosphorylase, glycogen, liver | 0.0255768 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0253986 |
| TPM3 | tropomyosin 3 | 0.0252848 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0252171 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0251287 |
| ARRDC3 | arrestin domain containing 3 | 0.0250911 |
| TES | testin LIM domain protein | 0.025011 |
| RPS12 | ribosomal protein S12 | 0.0247153 |
| RPL3 | ribosomal protein L3 | 0.0242848 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0240773 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0239941 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0238451 |
| PGK1 | phosphoglycerate kinase 1 | 0.0236133 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0232151 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0231105 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0229202 |
| UBC | ubiquitin C | 0.022791 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0225561 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0223088 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0218152 |
| RPS4X | ribosomal protein S4, X-linked | 0.0214664 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0214427 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0210477 |
| NCKAP1 | NCK-associated protein 1 | 0.0209937 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0209597 |
| FAM13A | family with sequence similarity 13, member A | 0.0209089 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0207417 |
| SERF2 | small EDRK-rich factor 2 | 0.0203504 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0203475 |
| FLNA | filamin A, alpha | 0.0202889 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0202136 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0198079 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0197903 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0197621 |
| RBM39 | RNA binding motif protein 39 | 0.0195703 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0195674 |
| KIF5B | kinesin family member 5B | 0.0192833 |
| GSTP1 | glutathione S-transferase pi 1 | 0.019279 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0192261 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0191823 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0189728 |
| SEC61G | Sec61 gamma subunit | 0.0189624 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0189608 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.17801 |
| TMSB10 | thymosin beta 10 | -0.146536 |
| EGFR | epidermal growth factor receptor | -0.133654 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.132231 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.122033 |
| EFNA5 | ephrin-A5 | -0.0975134 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0943091 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0800946 |
| ASPH | aspartate beta-hydroxylase | -0.0726836 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0692305 |
| ACTG1 | actin gamma 1 | -0.0645595 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.061429 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.057223 |
| CST3 | cystatin C | -0.0560438 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0555121 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0505231 |
| S100A10 | S100 calcium binding protein A10 | -0.0457447 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0456003 |
| CCND1 | cyclin D1 | -0.0455502 |
| TNS3 | tensin 3 | -0.0453955 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0447382 |
| RIN2 | Ras and Rab interactor 2 | -0.0434167 |
| AHNAK | AHNAK nucleoprotein | -0.0427619 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0420956 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0419391 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0402026 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0400637 |
| KRT7 | keratin 7, type II | -0.0382579 |
| KRT8 | keratin 8, type II | -0.0373947 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0359198 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0351431 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0343233 |
| HLA-B | major histocompatibility complex, class I, B | -0.0332686 |
| LMO7 | LIM domain 7 | -0.0331189 |
| RPS25 | ribosomal protein S25 | -0.0326356 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0324829 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0320595 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.031985 |
| RPS24 | ribosomal protein S24 | -0.0314633 |
| CP | ceruloplasmin (ferroxidase) | -0.0312677 |
| ANXA2 | annexin A2 | -0.0304019 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0303653 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0292192 |
| MYO1D | myosin ID | -0.0289734 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0281995 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0280237 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0279981 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0279839 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0274912 |
| RPL34 | ribosomal protein L34 | -0.0269936 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0267782 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0261476 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0261223 |
| TRIM56 | tripartite motif containing 56 | -0.0249912 |
| PRKCA | protein kinase C, alpha | -0.024498 |
| WASF2 | WAS protein family, member 2 | -0.0244899 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0241466 |
| CHML | choroideremia-like (Rab escort protein 2) | -0.0240847 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0238043 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0237852 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0237173 |
| S100A6 | S100 calcium binding protein A6 | -0.0236809 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0228148 |
| MYO1E | myosin IE | -0.0226252 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0223802 |
| JAK1 | Janus kinase 1 | -0.0220465 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0219684 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0219416 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0216561 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0216453 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0216431 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0216327 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0215861 |
| S100A9 | S100 calcium binding protein A9 | -0.0208054 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0207087 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0203968 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0201807 |
| PERP | PERP, TP53 apoptosis effector | -0.0200506 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0200224 |
| EHBP1 | EH domain binding protein 1 | -0.0199773 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0198443 |
| RAB27B | RAB27B, member RAS oncogene family | -0.019762 |
| KRT19 | keratin 19, type I | -0.0196009 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.019294 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0192863 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0190673 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0188659 |
| RNF213 | ring finger protein 213 | -0.0185035 |
| MX1 | MX dynamin-like GTPase 1 | -0.0184022 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.018323 |
| AGR2 | anterior gradient 2 | -0.0182325 |
| PCED1B | PC-esterase domain containing 1B | -0.0182318 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | -0.0181812 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0181562 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0180994 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0176713 |
| PTMA | prothymosin, alpha | -0.0175717 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0175348 |
| SDC4 | syndecan 4 | -0.0174179 |
| FOXP1 | forkhead box P1 | -0.0173269 |
