| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Docetaxel_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.176107 |
| MT2A | metallothionein 2A | 0.161863 |
| PM20D1 | peptidase M20 domain containing 1 | 0.14423 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0961867 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0844784 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0766183 |
| WWOX | WW domain containing oxidoreductase | 0.074253 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0674171 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0629163 |
| TUBB | tubulin, beta class I | 0.0611906 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0557256 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0543681 |
| RACK1 | receptor for activated C kinase 1 | 0.0535661 |
| KYNU | kynureninase | 0.0483221 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0438533 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0434091 |
| MKI67 | marker of proliferation Ki-67 | 0.0411516 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0410841 |
| CENPF | centromere protein F, 350/400kDa | 0.040324 |
| RPS3 | ribosomal protein S3 | 0.0391072 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.038901 |
| HSPA8 | heat shock 70kDa protein 8 | 0.038467 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0375399 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0372038 |
| ATXN1 | ataxin 1 | 0.0368434 |
| RAD51B | RAD51 paralog B | 0.0366085 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.036574 |
| RPL37A | ribosomal protein L37a | 0.0357768 |
| CTSL | cathepsin L | 0.0356911 |
| ASPH | aspartate beta-hydroxylase | 0.0351357 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0331816 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0326751 |
| PDE10A | phosphodiesterase 10A | 0.0316351 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0312496 |
| RPL23 | ribosomal protein L23 | 0.0310017 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0307069 |
| PRELID2 | PRELI domain containing 2 | 0.0304238 |
| RPS8 | ribosomal protein S8 | 0.0303124 |
| GOLGB1 | golgin B1 | 0.0302075 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0297865 |
| RPL35A | ribosomal protein L35a | 0.0293914 |
| RPLP1 | ribosomal protein, large, P1 | 0.0292787 |
| TPI1 | triosephosphate isomerase 1 | 0.0292307 |
| RPS12 | ribosomal protein S12 | 0.0292205 |
| AURKA | aurora kinase A | 0.0283013 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0280594 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0279196 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0274729 |
| CENPE | centromere protein E, 312kDa | 0.0270121 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0268525 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0267189 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0263954 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0257307 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0256812 |
| B2M | beta-2-microglobulin | 0.0254716 |
| RPL11 | ribosomal protein L11 | 0.0253017 |
| TUBA1B | tubulin, alpha 1b | 0.0251012 |
| INTS6 | integrator complex subunit 6 | 0.0250366 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0247909 |
| FHIT | fragile histidine triad | 0.0238485 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0235611 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0230018 |
| RPL12 | ribosomal protein L12 | 0.0228142 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0227204 |
| RNF213 | ring finger protein 213 | 0.0226214 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0225546 |
| AREG | amphiregulin | 0.0222562 |
| RPL31 | ribosomal protein L31 | 0.0221361 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0220787 |
| EXOC4 | exocyst complex component 4 | 0.0220488 |
| TBCA | tubulin folding cofactor A | 0.0217301 |
| ZNF638 | zinc finger protein 638 | 0.0214946 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0214903 |
| SKP1 | S-phase kinase-associated protein 1 | 0.021454 |
| ATP11A | ATPase, class VI, type 11A | 0.021333 |
| RPS21 | ribosomal protein S21 | 0.0213266 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0212177 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | 0.0211768 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0210904 |
| RRM2 | ribonucleotide reductase M2 | 0.0210591 |
| RPL37 | ribosomal protein L37 | 0.0210193 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0209748 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0208969 |
| RPL9 | ribosomal protein L9 | 0.0208183 |
| FLNA | filamin A, alpha | 0.0207827 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0204546 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0201935 |
| SGO2 | shugoshin 2 | 0.0197186 |
| PRKCE | protein kinase C, epsilon | 0.019265 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | 0.0192392 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0192025 |
| OSMR | oncostatin M receptor | 0.0191456 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0189879 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0188392 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0188153 |
| GLIS3 | GLIS family zinc finger 3 | 0.0187517 |
| STC1 | stanniocalcin 1 | 0.0186727 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.018116 |
| ATM | ATM serine/threonine kinase | 0.0179855 |
| RPL26 | ribosomal protein L26 | 0.0173423 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.315086 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.148209 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.109005 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.098685 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0913042 |
| ACTG1 | actin gamma 1 | -0.0821648 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0803327 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0743634 |
| ERBIN | erbb2 interacting protein | -0.0666166 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0643755 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0630294 |
| VIM | vimentin | -0.0623554 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0620987 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0617991 |
| POTEF | POTE ankyrin domain family, member F | -0.0575762 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0570817 |
| TMSB10 | thymosin beta 10 | -0.0555901 |
| S100A6 | S100 calcium binding protein A6 | -0.0543699 |
| TPD52 | tumor protein D52 | -0.0534574 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0523356 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0506763 |
| IGF2 | insulin-like growth factor 2 | -0.0497948 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0481967 |
| FTL | ferritin, light polypeptide | -0.0481519 |
| PARD3 | par-3 family cell polarity regulator | -0.0477843 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0469836 |
| WDR43 | WD repeat domain 43 | -0.0455864 |
| USP3 | ubiquitin specific peptidase 3 | -0.0453915 |
| COPA | coatomer protein complex, subunit alpha | -0.0438376 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0426335 |
| RTN4 | reticulon 4 | -0.0426175 |
| FGB | fibrinogen beta chain | -0.0414945 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0413925 |
| TFG | TRK-fused gene | -0.0405654 |
| RBM39 | RNA binding motif protein 39 | -0.0401185 |
| PLS3 | plastin 3 | -0.0395147 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0387707 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0381667 |
| MYOF | myoferlin | -0.0373836 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0372164 |
| ANXA2 | annexin A2 | -0.0363131 |
| PFN1 | profilin 1 | -0.036301 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0362299 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0356975 |
| PKM | pyruvate kinase, muscle | -0.0356744 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0355659 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.034226 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0341091 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0340337 |
| ZNF207 | zinc finger protein 207 | -0.033545 |
| FMNL2 | formin-like 2 | -0.0332994 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0332531 |
| PTK2 | protein tyrosine kinase 2 | -0.0326455 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0325347 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0324264 |
| SETD5 | SET domain containing 5 | -0.0323908 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0323149 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0320654 |
| MATR3 | matrin 3 | -0.0320334 |
| HMGA1 | high mobility group AT-hook 1 | -0.0319365 |
| APP | amyloid beta (A4) precursor protein | -0.0316907 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0303602 |
| TAGLN2 | transgelin 2 | -0.0298374 |
| ZNF292 | zinc finger protein 292 | -0.0294824 |
| AK1 | adenylate kinase 1 | -0.0293903 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0293446 |
| CHN1 | chimerin 1 | -0.029249 |
| MORF4L1 | mortality factor 4 like 1 | -0.0291491 |
| DENND4A | DENN/MADD domain containing 4A | -0.0288141 |
| PRR16 | proline rich 16 | -0.0286419 |
| TMEM123 | transmembrane protein 123 | -0.0283239 |
| RNF145 | ring finger protein 145 | -0.0279231 |
| MTMR3 | myotubularin related protein 3 | -0.0278994 |
| S100A10 | S100 calcium binding protein A10 | -0.0277714 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0275462 |
| HDAC9 | histone deacetylase 9 | -0.0275069 |
| RBM25 | RNA binding motif protein 25 | -0.0274887 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0274301 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0273165 |
| TMEM87A | transmembrane protein 87A | -0.0271987 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0267729 |
| FNBP1L | formin binding protein 1-like | -0.0267602 |
| RPS6 | ribosomal protein S6 | -0.026639 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0266011 |
| PCBP2 | poly(rC) binding protein 2 | -0.0266007 |
| UBC | ubiquitin C | -0.0265736 |
| RHOA | ras homolog family member A | -0.0265513 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0264088 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0260471 |
| BMPR1B | bone morphogenetic protein receptor, type IB | -0.0256569 |
| ECT2 | epithelial cell transforming 2 | -0.0255626 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0255578 |
| PHF20 | PHD finger protein 20 | -0.0253903 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0253602 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0251192 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0250933 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0248993 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0246573 |
| NOP58 | NOP58 ribonucleoprotein | -0.0243271 |
| RASAL2 | RAS protein activator like 2 | -0.0241958 |
