| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Docetaxel_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0968581 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0935665 |
| MCL1 | myeloid cell leukemia 1 | 0.0814544 |
| OSMR | oncostatin M receptor | 0.0746046 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0711559 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0700304 |
| PDE10A | phosphodiesterase 10A | 0.0644182 |
| HMGA2 | high mobility group AT-hook 2 | 0.057319 |
| VCL | vinculin | 0.0552059 |
| FMNL2 | formin-like 2 | 0.0548954 |
| RNF213 | ring finger protein 213 | 0.0533099 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0525587 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0524314 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0517104 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0504137 |
| WWOX | WW domain containing oxidoreductase | 0.0496487 |
| GRAMD1B | GRAM domain containing 1B | 0.0481714 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0473136 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0469771 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0468388 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0464176 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0442026 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.043986 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0435041 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0430138 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0426011 |
| IGF1R | insulin-like growth factor 1 receptor | 0.040978 |
| HOMER1 | homer scaffolding protein 1 | 0.0408006 |
| ACTG1 | actin gamma 1 | 0.0407742 |
| STC1 | stanniocalcin 1 | 0.0395137 |
| TMSB10 | thymosin beta 10 | 0.038653 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0372562 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0371516 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0361583 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0356454 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0352335 |
| LDHA | lactate dehydrogenase A | 0.0347743 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0337186 |
| RACK1 | receptor for activated C kinase 1 | 0.033678 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0336508 |
| INTS6 | integrator complex subunit 6 | 0.0330703 |
| RRM2 | ribonucleotide reductase M2 | 0.0329805 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0328803 |
| EXOC4 | exocyst complex component 4 | 0.0328098 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0327224 |
| EGR1 | early growth response 1 | 0.0326051 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.030641 |
| TPI1 | triosephosphate isomerase 1 | 0.0300796 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0299888 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0298035 |
| FLNA | filamin A, alpha | 0.0297887 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0297549 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0296634 |
| KLF6 | Kruppel-like factor 6 | 0.0295347 |
| NEK10 | NIMA-related kinase 10 | 0.0289393 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0288324 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0287938 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0286759 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0285269 |
| PRKCE | protein kinase C, epsilon | 0.0283496 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0283269 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0278677 |
| TPM4 | tropomyosin 4 | 0.0271486 |
| THADA | thyroid adenoma associated | 0.0270887 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0269688 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0265626 |
| TUBB | tubulin, beta class I | 0.0264815 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0264143 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0263007 |
| AEBP2 | AE binding protein 2 | 0.0258422 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0258312 |
| TRIM59 | tripartite motif containing 59 | 0.0255442 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0252255 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.025135 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0249897 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0249037 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0246451 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0246192 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.024317 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0241043 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0240638 |
| HLA-B | major histocompatibility complex, class I, B | 0.0237115 |
| BNC2 | basonuclin 2 | 0.0237104 |
| CDK17 | cyclin-dependent kinase 17 | 0.023366 |
| ATG7 | autophagy related 7 | 0.0233427 |
| RYR3 | ryanodine receptor 3 | 0.0231624 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0229713 |
| VCP | valosin containing protein | 0.0229343 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0228882 |
| MT2A | metallothionein 2A | 0.0228755 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0228355 |
| B2M | beta-2-microglobulin | 0.0226989 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | 0.0226854 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0226471 |
| SMAD3 | SMAD family member 3 | 0.0226372 |
| ATXN1 | ataxin 1 | 0.022267 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0217087 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0214624 |
| ACTN1 | actinin, alpha 1 | 0.0214507 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0213315 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.173334 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.117469 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0920605 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0872034 |
| TXNRD1 | thioredoxin reductase 1 | -0.081973 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.079611 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0784902 |
| PTMA | prothymosin, alpha | -0.0759348 |
| GOLGA4 | golgin A4 | -0.0707866 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0639353 |
| OGA | O-GlcNAcase | -0.0624751 |
| XPO1 | exportin 1 | -0.0610514 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0600887 |
| RTN4 | reticulon 4 | -0.0592138 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0565575 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0545158 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0505397 |
| PHIP | pleckstrin homology domain interacting protein | -0.050396 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0502172 |
| GOLGB1 | golgin B1 | -0.0496188 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0489489 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0488881 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0478864 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0477056 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0469749 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0455697 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0453295 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0449922 |
| ZFR | zinc finger RNA binding protein | -0.0444754 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0439158 |
| ZNF292 | zinc finger protein 292 | -0.0430027 |
| RPS6 | ribosomal protein S6 | -0.0419912 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0416445 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0415661 |
| RPS2 | ribosomal protein S2 | -0.0411688 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0397891 |
| CTTNBP2NL | CTTNBP2 N-terminal like | -0.0391463 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0375139 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0374519 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.037392 |
| GPHN | gephyrin | -0.0373092 |
| COPA | coatomer protein complex, subunit alpha | -0.037186 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.037129 |
| WDR45B | WD repeat domain 45B | -0.0353548 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0351335 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0350784 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0350064 |
| BBX | bobby sox homolog (Drosophila) | -0.0348548 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0347319 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0346528 |
| RSF1 | remodeling and spacing factor 1 | -0.0346514 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0343565 |
| MED13L | mediator complex subunit 13-like | -0.033703 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0336136 |
| RPS27 | ribosomal protein S27 | -0.0336026 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0333989 |
| RUSC2 | RUN and SH3 domain containing 2 | -0.0329572 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0329458 |
| SEPTIN7 | septin 7 | -0.0327064 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0323217 |
| COG5 | component of oligomeric golgi complex 5 | -0.0318623 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0318586 |
| MATR3 | matrin 3 | -0.031601 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0315958 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.031116 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0309574 |
| GOLT1B | golgi transport 1B | -0.0308954 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0307701 |
| MKI67 | marker of proliferation Ki-67 | -0.0306687 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0306431 |
| RPS29 | ribosomal protein S29 | -0.0304821 |
| PREPL | prolyl endopeptidase-like | -0.0303574 |
| PNN | pinin, desmosome associated protein | -0.0301973 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0299416 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0296776 |
| TMEM165 | transmembrane protein 165 | -0.0295736 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0293065 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | -0.0291899 |
| RPL38 | ribosomal protein L38 | -0.0291824 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0289581 |
| RAB10 | RAB10, member RAS oncogene family | -0.0289178 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0287705 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0287226 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | -0.0285644 |
| TFG | TRK-fused gene | -0.0284384 |
| HELZ | helicase with zinc finger | -0.0284161 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0281962 |
| EIF4B | eukaryotic translation initiation factor 4B | -0.0281642 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0280781 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0279341 |
| RECQL | RecQ helicase-like | -0.0278239 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0277628 |
| SBF2 | SET binding factor 2 | -0.0270953 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0270691 |
| CCND2 | cyclin D2 | -0.0270062 |
| TAOK1 | TAO kinase 1 | -0.0267559 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0266325 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0266275 |
| SRPK1 | SRSF protein kinase 1 | -0.026447 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.026426 |
