| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Docetaxel_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYO1E | myosin IE | 0.13964 |
| PM20D1 | peptidase M20 domain containing 1 | 0.131165 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.127932 |
| VMP1 | vacuole membrane protein 1 | 0.124477 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.12188 |
| LAMA4 | laminin, alpha 4 | 0.11942 |
| FAT1 | FAT atypical cadherin 1 | 0.115766 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.109963 |
| DSPP | dentin sialophosphoprotein | 0.109809 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.106028 |
| EHBP1 | EH domain binding protein 1 | 0.103269 |
| HMGA2 | high mobility group AT-hook 2 | 0.101608 |
| INTS6 | integrator complex subunit 6 | 0.100981 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0984953 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0945575 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0944505 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0910834 |
| ASPH | aspartate beta-hydroxylase | 0.0898961 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0869186 |
| FLNB | filamin B, beta | 0.0850772 |
| DST | dystonin | 0.0845499 |
| COL5A2 | collagen, type V, alpha 2 | 0.0838317 |
| ENAH | enabled homolog (Drosophila) | 0.0831933 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0831774 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.083128 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0824525 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0810683 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0794637 |
| PRELID2 | PRELI domain containing 2 | 0.0770864 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0758157 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0747874 |
| FLNA | filamin A, alpha | 0.072812 |
| SLK | STE20-like kinase | 0.0712703 |
| CDH13 | cadherin 13 | 0.0703792 |
| NAV1 | neuron navigator 1 | 0.0701843 |
| EZR | ezrin | 0.0697073 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0642886 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0633043 |
| ATXN1 | ataxin 1 | 0.0630961 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0630178 |
| RACK1 | receptor for activated C kinase 1 | 0.0618149 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0590953 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0585476 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0578111 |
| MT2A | metallothionein 2A | 0.0576943 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0573092 |
| DSTN | destrin (actin depolymerizing factor) | 0.0536707 |
| VCL | vinculin | 0.0521056 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0516138 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0503205 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0496085 |
| ERBIN | erbb2 interacting protein | 0.0495532 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0484266 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0478716 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0476344 |
| EXOC4 | exocyst complex component 4 | 0.0475922 |
| CD44 | CD44 molecule (Indian blood group) | 0.0471563 |
| RBM39 | RNA binding motif protein 39 | 0.0467379 |
| RPL37A | ribosomal protein L37a | 0.0464678 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0441898 |
| FMN1 | formin 1 | 0.0440678 |
| SMAD3 | SMAD family member 3 | 0.0435181 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0429212 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0424024 |
| SQSTM1 | sequestosome 1 | 0.0415943 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0408404 |
| ACTN4 | actinin, alpha 4 | 0.0402203 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0396106 |
| USP34 | ubiquitin specific peptidase 34 | 0.0389684 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0385702 |
| EGFR | epidermal growth factor receptor | 0.0283659 |
| PCBP2 | poly(rC) binding protein 2 | 0.0264531 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.0254586 |
| PARD3 | par-3 family cell polarity regulator | 0.0250759 |
| RPS12 | ribosomal protein S12 | 0.0244809 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0236986 |
| LDHA | lactate dehydrogenase A | 0.0234173 |
| RPL23 | ribosomal protein L23 | 0.0221315 |
| RTN4 | reticulon 4 | 0.0194991 |
| MYO5B | myosin VB | 0.0175601 |
| RPS6 | ribosomal protein S6 | 0.017257 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0157705 |
| RPLP0 | ribosomal protein, large, P0 | 0.0154077 |
| RPL19 | ribosomal protein L19 | 0.0128161 |
| RCOR1 | REST corepressor 1 | 0.0110632 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0110381 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.00990525 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.00679635 |
| GPHN | gephyrin | 0.00575561 |
| ANXA2 | annexin A2 | 0.00568357 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.00540261 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00523695 |
| PTMA | prothymosin, alpha | 0.00521424 |
| RPS19 | ribosomal protein S19 | 0.00293284 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.00245274 |
| ACTG1 | actin gamma 1 | 0.00220966 |
| RNF213 | ring finger protein 213 | 0.00182837 |
| PRRC2C | proline-rich coiled-coil 2C | 0.00150451 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.00111723 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 8.42431E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.193312 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.170304 |
| SNX9 | sorting nexin 9 | -0.140616 |
| RPS16 | ribosomal protein S16 | -0.135908 |
| VIM | vimentin | -0.13088 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.129645 |
| IGF2 | insulin-like growth factor 2 | -0.125528 |
| FNDC3B | fibronectin type III domain containing 3B | -0.121482 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.117401 |
| PGK1 | phosphoglycerate kinase 1 | -0.106311 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.100586 |
| CARD16 | caspase recruitment domain family, member 16 | -0.100246 |
| STAG2 | stromal antigen 2 | -0.0991444 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0987317 |
| RPLP1 | ribosomal protein, large, P1 | -0.0971974 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0959347 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0917086 |
| ITGA6 | integrin, alpha 6 | -0.0879124 |
| RPL26 | ribosomal protein L26 | -0.0863176 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0834397 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0824258 |
| WASF2 | WAS protein family, member 2 | -0.0801587 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.075804 |
| RPLP2 | ribosomal protein, large, P2 | -0.0744788 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0735267 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0687889 |
| NAV2 | neuron navigator 2 | -0.0681698 |
| JMJD1C | jumonji domain containing 1C | -0.0670592 |
| TMSB10 | thymosin beta 10 | -0.0668426 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.066279 |
| PRKCA | protein kinase C, alpha | -0.0649739 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0645839 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0638452 |
| SMYD3 | SET and MYND domain containing 3 | -0.0629545 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0624688 |
| FMNL2 | formin-like 2 | -0.0608961 |
| RBM25 | RNA binding motif protein 25 | -0.0604993 |
| EFNA5 | ephrin-A5 | -0.059366 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0578772 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0552247 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0543316 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0536115 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0533907 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.052423 |
| SBF2 | SET binding factor 2 | -0.0513604 |
| INHBA | inhibin, beta A | -0.0485174 |
| MYOF | myoferlin | -0.0482621 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0480612 |
| TENM3 | teneurin transmembrane protein 3 | -0.0463987 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0440798 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0436788 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0431903 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0414413 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0411759 |
| FAM13A | family with sequence similarity 13, member A | -0.0407817 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0402907 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0395466 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0394452 |
| LAMB3 | laminin, beta 3 | -0.0386925 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0377676 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0367615 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0360862 |
| NDRG1 | N-myc downstream regulated 1 | -0.0337866 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0294353 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0286572 |
| MED13L | mediator complex subunit 13-like | -0.0259849 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0257344 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.025056 |
| RPL35A | ribosomal protein L35a | -0.0250293 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0245059 |
| RPS8 | ribosomal protein S8 | -0.0231821 |
| RAB10 | RAB10, member RAS oncogene family | -0.0222218 |
| RORA | RAR-related orphan receptor A | -0.0219227 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0218797 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0203366 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0195178 |
| NFIA | nuclear factor I/A | -0.0194755 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.019155 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0190903 |
| CADM2 | cell adhesion molecule 2 | -0.0186494 |
| LMO7 | LIM domain 7 | -0.0182381 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0168585 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0164872 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0151908 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0151771 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0148332 |
| GPC6 | glypican 6 | -0.0148229 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0147793 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0143491 |
| FN1 | fibronectin 1 | -0.012604 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0109836 |
| MCL1 | myeloid cell leukemia 1 | -0.010297 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0100088 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.00909524 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.00896426 |
| GOLGA4 | golgin A4 | -0.00765852 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.00736167 |
| ENO1 | enolase 1, (alpha) | -0.00607319 |
| TXNRD1 | thioredoxin reductase 1 | -0.00554574 |
| CUX1 | cut-like homeobox 1 | -0.00358312 |
