| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Docetaxel_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | 0.116219 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0886296 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0773171 |
| DST | dystonin | 0.075233 |
| NTM | neurotrimin | 0.0691104 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0597447 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0594992 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0582261 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0503497 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0485865 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.046416 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.04571 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0445189 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0414056 |
| TXNRD1 | thioredoxin reductase 1 | 0.0411927 |
| PDGFC | platelet derived growth factor C | 0.0409799 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0407273 |
| SYT1 | synaptotagmin I | 0.0386768 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0375754 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0362403 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0361549 |
| CDH19 | cadherin 19, type 2 | 0.0323591 |
| SFRP4 | secreted frizzled-related protein 4 | 0.0321937 |
| RACK1 | receptor for activated C kinase 1 | 0.0321132 |
| UTRN | utrophin | 0.0311218 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0302768 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0294245 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.028764 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0287427 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0272536 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.027099 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0269968 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0264506 |
| METAP2 | methionyl aminopeptidase 2 | 0.0255922 |
| MB21D2 | Mab-21 domain containing 2 | 0.0246332 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0238207 |
| FLNA | filamin A, alpha | 0.0235286 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0234136 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0223672 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0223021 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0222779 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0220549 |
| SERTAD2 | SERTA domain containing 2 | 0.0219309 |
| ANXA1 | annexin A1 | 0.021844 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0215897 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0215463 |
| OPHN1 | oligophrenin 1 | 0.021511 |
| SKIL | SKI-like proto-oncogene | 0.0213167 |
| MEF2C | myocyte enhancer factor 2C | 0.0211727 |
| TUBA1B | tubulin, alpha 1b | 0.0210167 |
| HMGA2 | high mobility group AT-hook 2 | 0.0209879 |
| CREBBP | CREB binding protein | 0.0208995 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 | 0.0208954 |
| POTEF | POTE ankyrin domain family, member F | 0.0207039 |
| ZNF608 | zinc finger protein 608 | 0.0206872 |
| WDR75 | WD repeat domain 75 | 0.0204063 |
| POSTN | periostin, osteoblast specific factor | 0.020272 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0201729 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0198805 |
| TGFB2 | transforming growth factor, beta 2 | 0.0196397 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0195903 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0194658 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0194402 |
| SQSTM1 | sequestosome 1 | 0.01937 |
| CCNYL1 | cyclin Y-like 1 | 0.0193288 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0193121 |
| ZNF407 | zinc finger protein 407 | 0.0192557 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0190579 |
| SMAD6 | SMAD family member 6 | 0.0187905 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0187316 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0186021 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0183387 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0182618 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0182512 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0181565 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0181358 |
| RPL26 | ribosomal protein L26 | 0.0178896 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0178724 |
| UBN2 | ubinuclein 2 | 0.0177237 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0176917 |
| PTEN | phosphatase and tensin homolog | 0.0176258 |
| SCFD1 | sec1 family domain containing 1 | 0.0175868 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.0175083 |
| SUZ12 | SUZ12 polycomb repressive complex 2 subunit | 0.0174973 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0173857 |
| RBM28 | RNA binding motif protein 28 | 0.0173717 |
| TULP4 | tubby like protein 4 | 0.0170617 |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.016914 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0168358 |
| CCPG1 | cell cycle progression 1 | 0.0167254 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0167148 |
| SPAG9 | sperm associated antigen 9 | 0.0167005 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) | 0.0166828 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0166718 |
| TUBB2B | tubulin, beta 2B class IIb | 0.0163828 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0163513 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0163021 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0162776 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.016267 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | 0.0162153 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.146918 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.13455 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.125575 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.113043 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109241 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.106874 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.101621 |
| PHIP | pleckstrin homology domain interacting protein | -0.0957367 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0934883 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0884124 |
| TMSB10 | thymosin beta 10 | -0.0874738 |
| RPS16 | ribosomal protein S16 | -0.0859241 |
| MKI67 | marker of proliferation Ki-67 | -0.0855233 |
| VIM | vimentin | -0.0827531 |
| CENPF | centromere protein F, 350/400kDa | -0.0827187 |
| CADM2 | cell adhesion molecule 2 | -0.0824737 |
| AHNAK | AHNAK nucleoprotein | -0.0739786 |
| RPS6 | ribosomal protein S6 | -0.0733832 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0710276 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0689262 |
| COL1A2 | collagen, type I, alpha 2 | -0.0669962 |
| SRP54 | signal recognition particle 54kDa | -0.0668793 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0632722 |
| COL3A1 | collagen, type III, alpha 1 | -0.0622279 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0619289 |
| CALR | calreticulin | -0.0608771 |
| GPC3 | glypican 3 | -0.0593826 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0552954 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0547304 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0525239 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0504767 |
| RPS8 | ribosomal protein S8 | -0.0502536 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0489714 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0478121 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0476468 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0473789 |
| MAP4 | microtubule-associated protein 4 | -0.0453454 |
| RPLP1 | ribosomal protein, large, P1 | -0.0452521 |
| SETD5 | SET domain containing 5 | -0.0447288 |
| LRRC4C | leucine rich repeat containing 4C | -0.0442511 |
| PRELID2 | PRELI domain containing 2 | -0.0439047 |
| WASF2 | WAS protein family, member 2 | -0.0434429 |
| FBXO17 | F-box protein 17 | -0.0424487 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0423324 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0421827 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0419603 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0419053 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0415093 |
| NFIA | nuclear factor I/A | -0.0414131 |
| RPS25 | ribosomal protein S25 | -0.041157 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0398849 |
| RPL19 | ribosomal protein L19 | -0.0392885 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0389265 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0387678 |
| FTL | ferritin, light polypeptide | -0.0385512 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0384595 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0384318 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0383123 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0382747 |
| CUX1 | cut-like homeobox 1 | -0.0380189 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0379557 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0378046 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.037615 |
| RTN4 | reticulon 4 | -0.0372229 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0371891 |
| RPL32 | ribosomal protein L32 | -0.0363714 |
| NHSL1 | NHS-like 1 | -0.0363605 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0363458 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0358771 |
| PRTG | protogenin | -0.0357099 |
| RPS21 | ribosomal protein S21 | -0.0350536 |
| RBM20 | RNA binding motif protein 20 | -0.0348895 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0341663 |
| TOX | thymocyte selection-associated high mobility group box | -0.0341366 |
| PGK1 | phosphoglycerate kinase 1 | -0.0341151 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0340042 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0339786 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0339152 |
| SRPK2 | SRSF protein kinase 2 | -0.0329446 |
| JMJD1C | jumonji domain containing 1C | -0.0328114 |
| RPL36A | ribosomal protein L36a | -0.0327359 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.032715 |
| EVI5 | ecotropic viral integration site 5 | -0.0326601 |
| USP34 | ubiquitin specific peptidase 34 | -0.0326505 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0325412 |
| DENND1A | DENN/MADD domain containing 1A | -0.03225 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.031875 |
| CLIC4 | chloride intracellular channel 4 | -0.0318657 |
| RPL34 | ribosomal protein L34 | -0.031857 |
| CCNY | cyclin Y | -0.031465 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0313744 |
| GSE1 | Gse1 coiled-coil protein | -0.0313456 |
| TCF12 | transcription factor 12 | -0.0312241 |
| RPL31 | ribosomal protein L31 | -0.031015 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0306197 |
| SFTPA2 | surfactant protein A2 | -0.0304111 |
| THOC2 | THO complex 2 | -0.0302218 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0300926 |
| FBL | fibrillarin | -0.0300634 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0294572 |
