| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Docetaxel_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.10368 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.103035 |
| NRXN3 | neurexin 3 | 0.097396 |
| NDRG1 | N-myc downstream regulated 1 | 0.0933241 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0802491 |
| KYNU | kynureninase | 0.0769848 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0746362 |
| GLIS3 | GLIS family zinc finger 3 | 0.0688933 |
| HIP1 | huntingtin interacting protein 1 | 0.067552 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0598635 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0594003 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0564523 |
| ZNF292 | zinc finger protein 292 | 0.0518325 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.049892 |
| HPCAL1 | hippocalcin-like 1 | 0.0486027 |
| AOPEP | aminopeptidase O (putative) | 0.0480365 |
| RYBP | RING1 and YY1 binding protein | 0.0480291 |
| MEF2A | myocyte enhancer factor 2A | 0.0472204 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0442216 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0441446 |
| PRELID2 | PRELI domain containing 2 | 0.0435894 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0434363 |
| FAM20C | family with sequence similarity 20, member C | 0.0433078 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.042784 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0424522 |
| AHR | aryl hydrocarbon receptor | 0.042429 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0423715 |
| ECE1 | endothelin converting enzyme 1 | 0.0422546 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0416439 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0413672 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0412537 |
| RNF145 | ring finger protein 145 | 0.040771 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0405873 |
| TSPAN9 | tetraspanin 9 | 0.0403574 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0403281 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0402963 |
| PRSS23 | protease, serine, 23 | 0.03993 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 0.0395272 |
| CD44 | CD44 molecule (Indian blood group) | 0.0388726 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0382975 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0375634 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0371844 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0371355 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0357709 |
| PGK1 | phosphoglycerate kinase 1 | 0.0356495 |
| CD59 | CD59 molecule, complement regulatory protein | 0.034846 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0345692 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0341121 |
| FAM13A | family with sequence similarity 13, member A | 0.0335583 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0330922 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0325671 |
| INSIG2 | insulin induced gene 2 | 0.0317383 |
| STC1 | stanniocalcin 1 | 0.0314613 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0312296 |
| RAB31 | RAB31, member RAS oncogene family | 0.0310701 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0308508 |
| SQSTM1 | sequestosome 1 | 0.0303079 |
| BMERB1 | bMERB domain containing 1 | 0.0298214 |
| INTS6 | integrator complex subunit 6 | 0.0297611 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0295801 |
| SSH2 | slingshot protein phosphatase 2 | 0.0295526 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0295068 |
| VEGFC | vascular endothelial growth factor C | 0.0295011 |
| JPH2 | junctophilin 2 | 0.0294996 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0294313 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0290019 |
| SETBP1 | SET binding protein 1 | 0.0287535 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0287123 |
| FUS | FUS RNA binding protein | 0.0285777 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0285176 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0284777 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0284673 |
| TUBB | tubulin, beta class I | 0.0279542 |
| CLIC4 | chloride intracellular channel 4 | 0.0276386 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0276123 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0274989 |
| WLS | wntless Wnt ligand secretion mediator | 0.0273234 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.026895 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0268092 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0265049 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0264622 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0264327 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0263538 |
| HMGA2 | high mobility group AT-hook 2 | 0.0261276 |
| ACER3 | alkaline ceramidase 3 | 0.026051 |
| TAPBP | TAP binding protein (tapasin) | 0.0258185 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0256947 |
| SP100 | SP100 nuclear antigen | 0.0254841 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0254183 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0252812 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0252164 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0249903 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0249846 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0248556 |
| LAMB3 | laminin, beta 3 | 0.0247939 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0247026 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0245354 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0243858 |
| LOX | lysyl oxidase | 0.0243566 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0242283 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.15064 |
| MT2A | metallothionein 2A | -0.14933 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.118108 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.102121 |
| VIM | vimentin | -0.100725 |
| IL6 | interleukin 6 | -0.0862337 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0856178 |
| CDH13 | cadherin 13 | -0.0732696 |
| UBC | ubiquitin C | -0.0695165 |
| HLA-B | major histocompatibility complex, class I, B | -0.067243 |
| COL1A2 | collagen, type I, alpha 2 | -0.0668248 |
| EGFR | epidermal growth factor receptor | -0.0657114 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0560155 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0538884 |
| ACTG1 | actin gamma 1 | -0.0533051 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0524839 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0509714 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0507364 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0506335 |
| SDC4 | syndecan 4 | -0.0491497 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0489123 |
| RAI14 | retinoic acid induced 14 | -0.0485798 |
| PTMA | prothymosin, alpha | -0.0485702 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0443482 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0432434 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0393172 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0380337 |
| COL5A2 | collagen, type V, alpha 2 | -0.0379091 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0376972 |
| RPS3 | ribosomal protein S3 | -0.0373407 |
| SEC24D | SEC24 family member D | -0.0367885 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0367579 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0366788 |
| RPL23 | ribosomal protein L23 | -0.0364482 |
| COL1A1 | collagen, type I, alpha 1 | -0.0361474 |
| FLNB | filamin B, beta | -0.0356401 |
| RTN4 | reticulon 4 | -0.035522 |
| USP34 | ubiquitin specific peptidase 34 | -0.0350396 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0349388 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.0341782 |
| RPS6 | ribosomal protein S6 | -0.0341158 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0341074 |
| TPM2 | tropomyosin 2 (beta) | -0.033861 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0337524 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0333095 |
| CDK6 | cyclin-dependent kinase 6 | -0.0331938 |
| TPM4 | tropomyosin 4 | -0.0331243 |
| CALD1 | caldesmon 1 | -0.0330512 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0328063 |
| AHNAK | AHNAK nucleoprotein | -0.0323041 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0320723 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0319631 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0318652 |
| DEK | DEK proto-oncogene | -0.031747 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0315441 |
| POTEF | POTE ankyrin domain family, member F | -0.0313869 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0312047 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0311635 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0308779 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0306937 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0306566 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0303429 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0303287 |
| ANXA5 | annexin A5 | -0.0299792 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | -0.0297431 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.029638 |
| JAK1 | Janus kinase 1 | -0.0291645 |
| DST | dystonin | -0.0291457 |
| CFDP1 | craniofacial development protein 1 | -0.029039 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0288991 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0287987 |
| MCL1 | myeloid cell leukemia 1 | -0.0287423 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0286575 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.028576 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0284193 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0283055 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0283005 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.0282735 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0282314 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0278761 |
| NUCB2 | nucleobindin 2 | -0.0278596 |
| SPAG9 | sperm associated antigen 9 | -0.0278342 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0277816 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0277615 |
| MYO10 | myosin X | -0.0274055 |
| CTBP2 | C-terminal binding protein 2 | -0.0273715 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0273389 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0270583 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0270251 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0270207 |
| RBM25 | RNA binding motif protein 25 | -0.0268588 |
| CCNI | cyclin I | -0.0268509 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0266196 |
| TXNIP | thioredoxin interacting protein | -0.0265631 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0265212 |
| STK17A | serine/threonine kinase 17a | -0.0264953 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0264184 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0261296 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0257617 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0257225 |
