| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Docetaxel_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RACK1 | receptor for activated C kinase 1 | 0.0822615 |
| INTS6 | integrator complex subunit 6 | 0.0677994 |
| NDRG1 | N-myc downstream regulated 1 | 0.0639207 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0632344 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0620002 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0591466 |
| FLNA | filamin A, alpha | 0.0512284 |
| B2M | beta-2-microglobulin | 0.0472734 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0449636 |
| VCL | vinculin | 0.0431821 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0424785 |
| ENO1 | enolase 1, (alpha) | 0.0421656 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0421027 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.041845 |
| FAT1 | FAT atypical cadherin 1 | 0.0416738 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0413669 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0391017 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0386144 |
| TPM3 | tropomyosin 3 | 0.0384396 |
| RPS12 | ribosomal protein S12 | 0.0370412 |
| RPL9 | ribosomal protein L9 | 0.0367352 |
| ACTG1 | actin gamma 1 | 0.0366158 |
| GPATCH2L | G patch domain containing 2-like | 0.0355659 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0343653 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0340219 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0322731 |
| LRRC23 | leucine rich repeat containing 23 | 0.0313177 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0307002 |
| CENPF | centromere protein F, 350/400kDa | 0.0306129 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.030575 |
| RPL37 | ribosomal protein L37 | 0.0303316 |
| CTBP2 | C-terminal binding protein 2 | 0.0297985 |
| SMAD3 | SMAD family member 3 | 0.0291392 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0285989 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0279876 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0277801 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0276765 |
| RPL37A | ribosomal protein L37a | 0.0276696 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0274958 |
| RUNX1 | runt-related transcription factor 1 | 0.0271984 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0270969 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0269041 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0267398 |
| TUFT1 | tuftelin 1 | 0.0262981 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0259154 |
| TOP1 | topoisomerase (DNA) I | 0.0257103 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.025577 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0246765 |
| NPTN | neuroplastin | 0.0241354 |
| MT2A | metallothionein 2A | 0.0240592 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.023513 |
| SP100 | SP100 nuclear antigen | 0.0233812 |
| RCOR1 | REST corepressor 1 | 0.0229591 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0227462 |
| RPL11 | ribosomal protein L11 | 0.0225762 |
| CCDC138 | coiled-coil domain containing 138 | 0.0222863 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0221758 |
| LMO7 | LIM domain 7 | 0.0221466 |
| FTL | ferritin, light polypeptide | 0.0218356 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0216822 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0216295 |
| STC2 | stanniocalcin 2 | 0.0215464 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0213785 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0212454 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0210409 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0209373 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0209265 |
| GPC6 | glypican 6 | 0.0205328 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0204881 |
| ATF6 | activating transcription factor 6 | 0.0203931 |
| PCBP3 | poly(rC) binding protein 3 | 0.020201 |
| VIM | vimentin | 0.0201407 |
| RPLP0 | ribosomal protein, large, P0 | 0.0199523 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0199441 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0196953 |
| RPL31 | ribosomal protein L31 | 0.0195827 |
| FLNB | filamin B, beta | 0.0194834 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0189877 |
| TUBA1C | tubulin, alpha 1c | 0.0189154 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0188534 |
| RAB10 | RAB10, member RAS oncogene family | 0.018846 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0187776 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0187024 |
| AEBP2 | AE binding protein 2 | 0.0186753 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0184668 |
| MCL1 | myeloid cell leukemia 1 | 0.0184352 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0182286 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0181469 |
| BRD2 | bromodomain containing 2 | 0.0177216 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0177208 |
| MYO1E | myosin IE | 0.0176565 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0176507 |
| TUBB | tubulin, beta class I | 0.0176359 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0174671 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0174246 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0172232 |
| RPS2 | ribosomal protein S2 | 0.0172201 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0170546 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0169437 |
| RPL23 | ribosomal protein L23 | 0.0168826 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.166228 |
| NRG1 | neuregulin 1 | -0.153544 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.138486 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.13357 |
| FN1 | fibronectin 1 | -0.130981 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0924585 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0740089 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0731253 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0720845 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.068538 |
| ITGA1 | integrin, alpha 1 | -0.0685228 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0577436 |
| TMEM156 | transmembrane protein 156 | -0.0571215 |
| SYT1 | synaptotagmin I | -0.0547357 |
| TMEM165 | transmembrane protein 165 | -0.0534168 |
| CANX | calnexin | -0.0515072 |
| NRP1 | neuropilin 1 | -0.0511014 |
| S100A6 | S100 calcium binding protein A6 | -0.0487295 |
| PTMA | prothymosin, alpha | -0.0447473 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0438452 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0434853 |
| TMSB4X | thymosin beta 4, X-linked | -0.0420507 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0418626 |
| AOPEP | aminopeptidase O (putative) | -0.0407079 |
| OSMR | oncostatin M receptor | -0.040398 |
| FNBP1 | formin binding protein 1 | -0.0378835 |
| RAI14 | retinoic acid induced 14 | -0.0361089 |
| KLHL5 | kelch-like family member 5 | -0.0356266 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0348132 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0338751 |
| H1-0 | H1.0 linker histone | -0.0338248 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0335623 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0333828 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.032665 |
| ZNF292 | zinc finger protein 292 | -0.0323608 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0315619 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0311263 |
| CDC27 | cell division cycle 27 | -0.0310918 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0310096 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0307681 |
| SMOX | spermine oxidase | -0.0295957 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0295238 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0295231 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0289517 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0287898 |
| HMGA2 | high mobility group AT-hook 2 | -0.0285876 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0284386 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0276899 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0276754 |
| IER3 | immediate early response 3 | -0.0276607 |
| TXNIP | thioredoxin interacting protein | -0.0275285 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0271716 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0262637 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0262187 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0255523 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0254859 |
| EFNA5 | ephrin-A5 | -0.0253413 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0245776 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0245641 |
| AHR | aryl hydrocarbon receptor | -0.0243125 |
| RNF24 | ring finger protein 24 | -0.0239576 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.023651 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0227573 |
| MAP1B | microtubule-associated protein 1B | -0.0227248 |
| YME1L1 | YME1-like 1 ATPase | -0.0227162 |
| RUNX2 | runt-related transcription factor 2 | -0.0225429 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0224989 |
| TFG | TRK-fused gene | -0.0223915 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0223418 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0223071 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0222919 |
| ETV1 | ets variant 1 | -0.0222858 |
| SETD5 | SET domain containing 5 | -0.0216755 |
| RNF145 | ring finger protein 145 | -0.0216659 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0215424 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0214825 |
| NEK7 | NIMA-related kinase 7 | -0.0213579 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0212202 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0211277 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0209432 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0208948 |
| IL6 | interleukin 6 | -0.0208088 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0207807 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0207413 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0205277 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.020489 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0204449 |
| FAM13A | family with sequence similarity 13, member A | -0.0204063 |
| RTN4 | reticulon 4 | -0.0203505 |
| GLIS3 | GLIS family zinc finger 3 | -0.0202448 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0202258 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0202248 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0200827 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.020072 |
| S100A9 | S100 calcium binding protein A9 | -0.0200215 |
| DENND4C | DENN/MADD domain containing 4C | -0.0199409 |
| PGK1 | phosphoglycerate kinase 1 | -0.0198103 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0197738 |
| RANBP17 | RAN binding protein 17 | -0.0197228 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.019425 |
