Dorzolamide Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description 5,6-Dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide in which hydrogens at the 4 and 6 positions are substituted by ethylamino and methyl groups, respectively (4S, trans-configuration). A carbonic anhydrase inhibitor, it is used as the hydrochloride in ophthalmic solutions to lower increased intraocular pressure in the treatment of open-angle glaucoma and ocular hypertension. (Chemical Entities of Biological Interest Ontology, CHEBI_4702)
External Link http://www.hmdb.ca/metabolites/HMDB15007
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Genes

5 interacting proteins for the Dorzolamide metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
CA1 carbonic anhydrase I
CA2 carbonic anhydrase II
CA4 carbonic anhydrase IV
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4