Downregulation of ERBB2 signaling Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-8863795
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Genes

29 proteins participating in the Downregulation of ERBB2 signaling pathway from the Reactome Pathways 2024 dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
BTC betacellulin
CDC37 cell division cycle 37
CUL5 cullin 5
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ERBIN erbb2 interacting protein
EREG epiregulin
HBEGF heparin-binding EGF-like growth factor
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
MATK megakaryocyte-associated tyrosine kinase
NRG1 neuregulin 1
NRG2 neuregulin 2
NRG3 neuregulin 3
NRG4 neuregulin 4
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RPS27A ribosomal protein S27a
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
USP8 ubiquitin specific peptidase 8