Downregulation of SMAD2/3:SMAD4 transcriptional activity Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-2173795
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Genes

31 proteins participating in the Downregulation of SMAD2/3:SMAD4 transcriptional activity pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide
HDAC1 histone deacetylase 1
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
RNF111 ring finger protein 111
RPS27A ribosomal protein S27a
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SKI SKI proto-oncogene
SKIL SKI-like proto-oncogene
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD7 SMAD family member 7
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNW1 SNW domain containing 1
STAT1 signal transducer and activator of transcription 1, 91kDa
TGIF1 TGFB-induced factor homeobox 1
TGIF2 TGFB-induced factor homeobox 2
TRIM33 tripartite motif containing 33
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D3 ubiquitin-conjugating enzyme E2D 3
USP9X ubiquitin specific peptidase 9, X-linked
WWTR1 WW domain containing transcription regulator 1