| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxorubicin (hydrochloride) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Doxorubicin (hydrochloride)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMTK2 | lemur tyrosine kinase 2 | 0.0874232 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.079694 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0721968 |
| SMAD3 | SMAD family member 3 | 0.0619525 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0579072 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0545566 |
| SLMAP | sarcolemma associated protein | 0.0532944 |
| FAM107B | family with sequence similarity 107, member B | 0.0519828 |
| OGA | O-GlcNAcase | 0.0506604 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0500884 |
| PLEC | plectin | 0.0494225 |
| NEK7 | NIMA-related kinase 7 | 0.0486246 |
| ITGA6 | integrin, alpha 6 | 0.0482003 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0478304 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0450682 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0450509 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0430356 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0425811 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0416926 |
| TOP1 | topoisomerase (DNA) I | 0.0410122 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0405231 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0390567 |
| PCBP2 | poly(rC) binding protein 2 | 0.0390275 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0390063 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0389565 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0384264 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0381074 |
| MED13L | mediator complex subunit 13-like | 0.0374317 |
| CCNL1 | cyclin L1 | 0.037222 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.0371301 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0348046 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0341574 |
| RTN4 | reticulon 4 | 0.0340229 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0339005 |
| ZNF292 | zinc finger protein 292 | 0.0333783 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0332618 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0332151 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0324097 |
| MATR3 | matrin 3 | 0.0316668 |
| MYO6 | myosin VI | 0.0308802 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0305134 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0302797 |
| ARRDC3 | arrestin domain containing 3 | 0.0301152 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0299784 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.029228 |
| USP3 | ubiquitin specific peptidase 3 | 0.0285971 |
| NPTN | neuroplastin | 0.0282639 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0281329 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.027839 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0278078 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0278064 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0275986 |
| FOXO3 | forkhead box O3 | 0.0275693 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0274422 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.027202 |
| JMJD1C | jumonji domain containing 1C | 0.0270709 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0266877 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0266013 |
| TMEM41B | transmembrane protein 41B | 0.0264043 |
| ATP11B | ATPase, class VI, type 11B | 0.0261004 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0260424 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0259507 |
| CDC42SE2 | CDC42 small effector 2 | 0.0257953 |
| CERT1 | ceramide transporter 1 | 0.0257405 |
| KIF5B | kinesin family member 5B | 0.0256541 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0255188 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0250054 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.024978 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0245337 |
| XPO1 | exportin 1 | 0.0241606 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0240583 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0240467 |
| ATP13A3 | ATPase type 13A3 | 0.0238371 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0232556 |
| PTK2 | protein tyrosine kinase 2 | 0.0232532 |
| SERTAD2 | SERTA domain containing 2 | 0.0232463 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0230672 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0230425 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0228032 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0224484 |
| MYOF | myoferlin | 0.0224273 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0223507 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0223256 |
| ANLN | anillin, actin binding protein | 0.0220901 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0218767 |
| PTEN | phosphatase and tensin homolog | 0.0216283 |
| HPCAL1 | hippocalcin-like 1 | 0.0216241 |
| NUP58 | nucleoporin 58 | 0.0214165 |
| CUL3 | cullin 3 | 0.0214083 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.021392 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0212305 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0211123 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 0.0210208 |
| OLA1 | Obg-like ATPase 1 | 0.021003 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0209196 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0208314 |
| VCL | vinculin | 0.0208275 |
| CAPRIN2 | caprin family member 2 | 0.0207351 |
| CPNE8 | copine VIII | 0.0206881 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0205819 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | -0.226314 |
| TMSB10 | thymosin beta 10 | -0.201143 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.168365 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.163718 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.139183 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.129825 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.126949 |
| LAMA4 | laminin, alpha 4 | -0.109443 |
| EGFR | epidermal growth factor receptor | -0.102385 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0975392 |
| FLNB | filamin B, beta | -0.0966923 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0784335 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0752436 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0724876 |
| NPSR1 | neuropeptide S receptor 1 | -0.0663338 |
| RASAL2 | RAS protein activator like 2 | -0.0642232 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0633931 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0612724 |
| HMGA2 | high mobility group AT-hook 2 | -0.0608073 |
| LAMC2 | laminin, gamma 2 | -0.0599199 |
| DIAPH2 | diaphanous-related formin 2 | -0.0597941 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0595091 |
| FERMT1 | fermitin family member 1 | -0.0591729 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0566756 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.05632 |
| HDAC9 | histone deacetylase 9 | -0.0556869 |
| KLK10 | kallikrein-related peptidase 10 | -0.0551621 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0544391 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0534128 |
| LMO7 | LIM domain 7 | -0.0533561 |
| SP100 | SP100 nuclear antigen | -0.052792 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0524278 |
| TXNIP | thioredoxin interacting protein | -0.0506929 |
| FBXO11 | F-box protein 11 | -0.0505152 |
| INTS6 | integrator complex subunit 6 | -0.0463616 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0460543 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0455875 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0454828 |
| ANXA2 | annexin A2 | -0.0450209 |
| EZR | ezrin | -0.0444722 |
| RPL37A | ribosomal protein L37a | -0.0442001 |
| SVIL | supervillin | -0.0427429 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0420821 |
| RRBP1 | ribosome binding protein 1 | -0.0412882 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0412729 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0412156 |
| RPS3 | ribosomal protein S3 | -0.0410693 |
| PMM2 | phosphomannomutase 2 | -0.0404434 |
| TRRAP | transformation/transcription domain-associated protein | -0.0402183 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0398904 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0393624 |
| ACTN4 | actinin, alpha 4 | -0.0391805 |
| S100A11 | S100 calcium binding protein A11 | -0.0387767 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0385313 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.0381701 |
| TGFA | transforming growth factor, alpha | -0.0371459 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0368945 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0368685 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0367507 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0366119 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0355089 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0352889 |
| CLMP | CXADR-like membrane protein | -0.0348268 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0338605 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0331704 |
| GOLGB1 | golgin B1 | -0.0327091 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0326434 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0325503 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0323427 |
| AK1 | adenylate kinase 1 | -0.032077 |
| PTMA | prothymosin, alpha | -0.0319978 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0317628 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0313901 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0313208 |
| DENND2C | DENN/MADD domain containing 2C | -0.0312545 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.030803 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0305059 |
| RPL23 | ribosomal protein L23 | -0.0303999 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.030378 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0303715 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0298064 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.029516 |
| S100A4 | S100 calcium binding protein A4 | -0.0295041 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.029398 |
| CDK13 | cyclin-dependent kinase 13 | -0.0292042 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.029108 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0290221 |
| RPL34 | ribosomal protein L34 | -0.0287992 |
| NABP1 | nucleic acid binding protein 1 | -0.028351 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | -0.0280109 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0276953 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0276727 |
| TJP1 | tight junction protein 1 | -0.0276589 |
| EGR1 | early growth response 1 | -0.0273833 |
| RPLP1 | ribosomal protein, large, P1 | -0.0273046 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.027233 |
| TMEM263 | transmembrane protein 263 | -0.0271449 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0271115 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0271006 |
| NBEAL1 | neurobeachin-like 1 | -0.0270927 |
