| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxorubicin (hydrochloride) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Doxorubicin (hydrochloride)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.181522 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0881475 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0761842 |
| FN1 | fibronectin 1 | 0.0627206 |
| TMSB10 | thymosin beta 10 | 0.059392 |
| CALR | calreticulin | 0.0523649 |
| EPHA4 | EPH receptor A4 | 0.0482584 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0474087 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.041484 |
| FLNA | filamin A, alpha | 0.0408839 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0402675 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0396898 |
| GDF15 | growth differentiation factor 15 | 0.0383625 |
| PTCHD4 | patched domain containing 4 | 0.0369174 |
| VIM | vimentin | 0.0344813 |
| HLA-A | major histocompatibility complex, class I, A | 0.0342136 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0335121 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.032747 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0323475 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0320696 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0318845 |
| CADM1 | cell adhesion molecule 1 | 0.031873 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0315345 |
| RPL13A | ribosomal protein L13a | 0.0302328 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0301559 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.029587 |
| B2M | beta-2-microglobulin | 0.0291854 |
| SERINC5 | serine incorporator 5 | 0.0283369 |
| KALRN | kalirin, RhoGEF kinase | 0.0279317 |
| RPL35A | ribosomal protein L35a | 0.0275757 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0273031 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0263742 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.025907 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.02573 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0254881 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0254682 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0254414 |
| HLA-B | major histocompatibility complex, class I, B | 0.0253708 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0252219 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0246304 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0245371 |
| AK1 | adenylate kinase 1 | 0.0244892 |
| KCTD8 | potassium channel tetramerization domain containing 8 | 0.0243646 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0242302 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.0236261 |
| PCBP2 | poly(rC) binding protein 2 | 0.0235538 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.023307 |
| NOPCHAP1 | NOP protein chaperone 1 | 0.0232627 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0229767 |
| KLHL29 | kelch-like family member 29 | 0.0229433 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.022822 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0225748 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0224235 |
| FBXO22 | F-box protein 22 | 0.0220473 |
| PRKCA | protein kinase C, alpha | 0.0215173 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0211813 |
| HYOU1 | hypoxia up-regulated 1 | 0.0208023 |
| CANX | calnexin | 0.0204755 |
| RPL37A | ribosomal protein L37a | 0.0201561 |
| POLH | polymerase (DNA directed), eta | 0.0198284 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0197256 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0195958 |
| KIF26B | kinesin family member 26B | 0.0191838 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.019043 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0186827 |
| BSG | basigin (Ok blood group) | 0.0184933 |
| GANAB | glucosidase, alpha; neutral AB | 0.0181211 |
| RPL37 | ribosomal protein L37 | 0.0179338 |
| MLEC | malectin | 0.0177355 |
| PCDH9 | protocadherin 9 | 0.0175934 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.0174594 |
| RPS19 | ribosomal protein S19 | 0.0173921 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0171293 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0168211 |
| HLA-E | major histocompatibility complex, class I, E | 0.0166564 |
| GSE1 | Gse1 coiled-coil protein | 0.0166009 |
| YBX1 | Y box binding protein 1 | 0.0163655 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0162523 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0161562 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0157469 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0157251 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0156332 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0154299 |
| ANXA4 | annexin A4 | 0.0153194 |
| ASTN2 | astrotactin 2 | 0.0152635 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0152611 |
| TMEM117 | transmembrane protein 117 | 0.0150419 |
| FDXR | ferredoxin reductase | 0.0149987 |
| OXR1 | oxidation resistance 1 | 0.0148826 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0148823 |
| RPS4X | ribosomal protein S4, X-linked | 0.0148463 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.014803 |
| THBS1 | thrombospondin 1 | 0.0147239 |
| TMSB4X | thymosin beta 4, X-linked | 0.0146996 |
| GPHN | gephyrin | 0.0145751 |
| RRM2B | ribonucleotide reductase M2 B (TP53 inducible) | 0.0145439 |
| DGKH | diacylglycerol kinase, eta | 0.0144915 |
| CYCS | cytochrome c, somatic | 0.0144906 |
| GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C | 0.0144388 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0143921 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.300428 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0950595 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0943652 |
| STC1 | stanniocalcin 1 | -0.0806905 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0790317 |
| ASPH | aspartate beta-hydroxylase | -0.0763687 |
| MT2A | metallothionein 2A | -0.074754 |
| RTN4 | reticulon 4 | -0.0709903 |
| CD44 | CD44 molecule (Indian blood group) | -0.0672645 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0606431 |
| GLIS3 | GLIS family zinc finger 3 | -0.0588181 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0577275 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.056026 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0559597 |
| TXNIP | thioredoxin interacting protein | -0.0538965 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0527556 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0519728 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.051138 |
| NDRG1 | N-myc downstream regulated 1 | -0.0468863 |
| MAP1B | microtubule-associated protein 1B | -0.0457814 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0444865 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0443049 |
| GOLGA4 | golgin A4 | -0.0433886 |
| CENPF | centromere protein F, 350/400kDa | -0.0428973 |
| NF1 | neurofibromin 1 | -0.042684 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0416762 |
| TXNRD1 | thioredoxin reductase 1 | -0.0412419 |
| SMAD3 | SMAD family member 3 | -0.0410718 |
| OSMR | oncostatin M receptor | -0.0409811 |
| CLTC | clathrin, heavy chain (Hc) | -0.0403936 |
| GOLGB1 | golgin B1 | -0.040139 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0400715 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0400444 |
| USP34 | ubiquitin specific peptidase 34 | -0.0389158 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0382068 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0381874 |
| ATXN1 | ataxin 1 | -0.0376963 |
| SBF2 | SET binding factor 2 | -0.0371991 |
| MSN | moesin | -0.0369359 |
| CALU | calumenin | -0.0365929 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0358616 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0347156 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0346454 |
| KYNU | kynureninase | -0.0345853 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0343119 |
| ATP13A3 | ATPase type 13A3 | -0.0336922 |
| RNF216 | ring finger protein 216 | -0.0336109 |
| MKI67 | marker of proliferation Ki-67 | -0.0332563 |
| COPA | coatomer protein complex, subunit alpha | -0.0324214 |
| SEC24D | SEC24 family member D | -0.0323802 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0323043 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0322252 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0318704 |
| RBM39 | RNA binding motif protein 39 | -0.0318336 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0317221 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0313444 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0306915 |
| IL6ST | interleukin 6 signal transducer | -0.0306897 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0303735 |
| PTK2 | protein tyrosine kinase 2 | -0.0302774 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0301316 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0301277 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0301254 |
| SEC24A | SEC24 family member A | -0.0300897 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0299852 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0299732 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0298684 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0297815 |
| SETD5 | SET domain containing 5 | -0.0292657 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0292466 |
| ZNF292 | zinc finger protein 292 | -0.0292096 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0284446 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0282424 |
| ANO6 | anoctamin 6 | -0.0282373 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0282278 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0281824 |
| CLINT1 | clathrin interactor 1 | -0.0279899 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0276898 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0267847 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0267118 |
| RPS2 | ribosomal protein S2 | -0.0265362 |
| SMYD3 | SET and MYND domain containing 3 | -0.0264142 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0261722 |
| ERBIN | erbb2 interacting protein | -0.02592 |
| VMP1 | vacuole membrane protein 1 | -0.0258455 |
| ANLN | anillin, actin binding protein | -0.0257302 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0255774 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0252344 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0252216 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0252004 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0251894 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.025133 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0251154 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0250559 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0250501 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0249757 |
| DST | dystonin | -0.024839 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | -0.0247389 |
| PHF14 | PHD finger protein 14 | -0.0246992 |
| RRBP1 | ribosome binding protein 1 | -0.0246666 |
