| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxorubicin (hydrochloride) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Doxorubicin (hydrochloride)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLIT2 | slit homolog 2 (Drosophila) | 0.0780364 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.065892 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0645822 |
| FN1 | fibronectin 1 | 0.0633173 |
| HLA-E | major histocompatibility complex, class I, E | 0.0627315 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0563949 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0507409 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0506456 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.0462327 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0442754 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0439324 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0438783 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0437373 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0427936 |
| TLE4 | transducin-like enhancer of split 4 | 0.0414526 |
| FLNA | filamin A, alpha | 0.0410769 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0399783 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0372716 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0364058 |
| ZNF804A | zinc finger protein 804A | 0.0359733 |
| DIAPH3 | diaphanous-related formin 3 | 0.0358035 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0346189 |
| HLA-A | major histocompatibility complex, class I, A | 0.031943 |
| RNF213 | ring finger protein 213 | 0.0317075 |
| ZNF432 | zinc finger protein 432 | 0.0316933 |
| FNIP1 | folliculin interacting protein 1 | 0.0314995 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0311097 |
| CAVIN1 | caveolae associated protein 1 | 0.0306089 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0304214 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0299794 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0297951 |
| E2F3 | E2F transcription factor 3 | 0.0293723 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0290876 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0290031 |
| UBAP2 | ubiquitin associated protein 2 | 0.0290002 |
| ASPH | aspartate beta-hydroxylase | 0.0288689 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0287751 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0287345 |
| CENPP | centromere protein P | 0.0285206 |
| MKI67 | marker of proliferation Ki-67 | 0.027502 |
| AHNAK | AHNAK nucleoprotein | 0.0272265 |
| PRKCA | protein kinase C, alpha | 0.0268674 |
| HMGB2 | high mobility group box 2 | 0.0266672 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0261801 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0260016 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0259419 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0258027 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0254529 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0250418 |
| SMAD3 | SMAD family member 3 | 0.024988 |
| TOP1 | topoisomerase (DNA) I | 0.0248131 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | 0.0244853 |
| HDAC9 | histone deacetylase 9 | 0.0242741 |
| HLA-C | major histocompatibility complex, class I, C | 0.0242017 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0240773 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0237057 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0237036 |
| CANX | calnexin | 0.0236862 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0233868 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0229869 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0224668 |
| DGKH | diacylglycerol kinase, eta | 0.0224344 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0224033 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0223836 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0223424 |
| ZNF841 | zinc finger protein 841 | 0.0220489 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0218647 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0217526 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.021515 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0214603 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0214578 |
| PSPC1 | paraspeckle component 1 | 0.0213908 |
| RIGI | RNA sensor RIG-I | 0.0213442 |
| DENND4A | DENN/MADD domain containing 4A | 0.0210753 |
| SERPINA2 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) | 0.0210551 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.021028 |
| MED13 | mediator complex subunit 13 | 0.0207688 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0206592 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0205537 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0205242 |
| VCL | vinculin | 0.0204785 |
| EPHA4 | EPH receptor A4 | 0.0203341 |
| PCBP2 | poly(rC) binding protein 2 | 0.0201565 |
| CDK19 | cyclin-dependent kinase 19 | 0.0195699 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0195591 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0194194 |
| FSTL1 | follistatin-like 1 | 0.0193509 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0192645 |
| NAV2 | neuron navigator 2 | 0.019128 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0189646 |
| RGS7 | regulator of G-protein signaling 7 | 0.0186097 |
| HELLS | helicase, lymphoid-specific | 0.0185293 |
| AOPEP | aminopeptidase O (putative) | 0.0182933 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0181982 |
| PKP4 | plakophilin 4 | 0.018103 |
| KNTC1 | kinetochore associated 1 | 0.0180731 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0178557 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0177241 |
| ACTN1 | actinin, alpha 1 | 0.0177048 |
| CLSPN | claspin | 0.0176159 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.25781 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.250952 |
| FTL | ferritin, light polypeptide | -0.22989 |
| MT2A | metallothionein 2A | -0.150381 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.119165 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0885075 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0850361 |
| MT1X | metallothionein 1X | -0.081639 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0689678 |
| DEK | DEK proto-oncogene | -0.0625345 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0611121 |
| NDRG1 | N-myc downstream regulated 1 | -0.0570064 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0561605 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0531362 |
| TXNRD1 | thioredoxin reductase 1 | -0.0505441 |
| FLNB | filamin B, beta | -0.0470659 |
| ADM | adrenomedullin | -0.0454112 |
| ENO1 | enolase 1, (alpha) | -0.0428961 |
| SLC12A8 | solute carrier family 12, member 8 | -0.0404482 |
| FOSL1 | FOS-like antigen 1 | -0.0398661 |
| PLIN2 | perilipin 2 | -0.0393721 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0388986 |
| GOLGA4 | golgin A4 | -0.0387274 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0382725 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.037996 |
| LDHA | lactate dehydrogenase A | -0.0371689 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0361763 |
| ARF4 | ADP-ribosylation factor 4 | -0.0340955 |
| POTEF | POTE ankyrin domain family, member F | -0.0326595 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0320611 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0315821 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0306621 |
| UBC | ubiquitin C | -0.0304122 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0301478 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0300329 |
| PFN1 | profilin 1 | -0.0300153 |
| TPD52 | tumor protein D52 | -0.0298281 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0290703 |
| CTSD | cathepsin D | -0.0290409 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0288851 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.028679 |
| RPS6 | ribosomal protein S6 | -0.0286051 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0284521 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0280877 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0280875 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0275276 |
| SBF2 | SET binding factor 2 | -0.0266739 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0264415 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.025079 |
| FNDC3B | fibronectin type III domain containing 3B | -0.024631 |
| TUBB | tubulin, beta class I | -0.0245364 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.024111 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0240692 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.023898 |
| LOC112694756 | uncharaterized LOC112694756 | -0.023495 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0233126 |
| MAP1B | microtubule-associated protein 1B | -0.023191 |
| ZNF292 | zinc finger protein 292 | -0.0229337 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0223771 |
| ACTG1 | actin gamma 1 | -0.0222491 |
| PGK1 | phosphoglycerate kinase 1 | -0.0222238 |
| PLK2 | polo-like kinase 2 | -0.0221628 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0220329 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0218908 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0217259 |
| TRAM1 | translocation associated membrane protein 1 | -0.0214756 |
| TFG | TRK-fused gene | -0.0213475 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0212898 |
| AFAP1 | actin filament associated protein 1 | -0.02082 |
| S100A10 | S100 calcium binding protein A10 | -0.0206139 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0203212 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0200704 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0200091 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0197995 |
| NPPB | natriuretic peptide B | -0.0193249 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0192629 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0192447 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0188643 |
| TPM4 | tropomyosin 4 | -0.0188266 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0187407 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.01854 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0185113 |
| JUN | jun proto-oncogene | -0.018466 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.0184191 |
| NUP58 | nucleoporin 58 | -0.0183836 |
| SETD5 | SET domain containing 5 | -0.0181967 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0181948 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0181184 |
| PFN2 | profilin 2 | -0.0176487 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0175919 |
| S100A6 | S100 calcium binding protein A6 | -0.0175899 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.017486 |
| FAM162A | family with sequence similarity 162, member A | -0.0172872 |
| EGR1 | early growth response 1 | -0.0172665 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0171476 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0171336 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0169526 |
| COG6 | component of oligomeric golgi complex 6 | -0.016942 |
| PTMA | prothymosin, alpha | -0.016931 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0168915 |
