| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxorubicin (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Doxorubicin (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.0848499 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0690376 |
| PCBP2 | poly(rC) binding protein 2 | 0.05442 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0466981 |
| FLNA | filamin A, alpha | 0.0456377 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0424717 |
| TMSB10 | thymosin beta 10 | 0.0389567 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0371879 |
| RPL13A | ribosomal protein L13a | 0.0344115 |
| EPHA4 | EPH receptor A4 | 0.0340515 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0313232 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0309162 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0297498 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0278086 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0269483 |
| CD109 | CD109 molecule | 0.0246734 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.024599 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0243774 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0236281 |
| ANXA2 | annexin A2 | 0.0230912 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0228201 |
| YBX1 | Y box binding protein 1 | 0.0220248 |
| RPSA | ribosomal protein SA | 0.0219421 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0215607 |
| MLEC | malectin | 0.0214675 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0213194 |
| TPM3 | tropomyosin 3 | 0.0212183 |
| NOPCHAP1 | NOP protein chaperone 1 | 0.0193702 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.019206 |
| CANX | calnexin | 0.0190346 |
| APAF1 | apoptotic peptidase activating factor 1 | 0.0188661 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.018616 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0180198 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0177636 |
| OGA | O-GlcNAcase | 0.0176651 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0175081 |
| CALR | calreticulin | 0.0174286 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0170351 |
| POLH | polymerase (DNA directed), eta | 0.0170077 |
| PLK2 | polo-like kinase 2 | 0.0168123 |
| BSG | basigin (Ok blood group) | 0.0166141 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0161885 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0159729 |
| RPS19 | ribosomal protein S19 | 0.015831 |
| FN1 | fibronectin 1 | 0.0148179 |
| RPS4X | ribosomal protein S4, X-linked | 0.014524 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0144818 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.014275 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0142719 |
| SERINC5 | serine incorporator 5 | 0.0140662 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0140398 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.013903 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0138163 |
| FDXR | ferredoxin reductase | 0.0136236 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0136111 |
| GNAS | GNAS complex locus | 0.0135637 |
| RRM2B | ribonucleotide reductase M2 B (TP53 inducible) | 0.0133074 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0131798 |
| PTCHD4 | patched domain containing 4 | 0.0130007 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0128565 |
| ETNK1 | ethanolamine kinase 1 | 0.0127529 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0126419 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 0.0126372 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0126032 |
| HLA-E | major histocompatibility complex, class I, E | 0.0124704 |
| GANAB | glucosidase, alpha; neutral AB | 0.012242 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0122247 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0121597 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0120595 |
| HYOU1 | hypoxia up-regulated 1 | 0.0117865 |
| TOP1 | topoisomerase (DNA) I | 0.0117118 |
| ATF3 | activating transcription factor 3 | 0.0116945 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0116906 |
| SMAP2 | small ArfGAP2 | 0.0116716 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0116664 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0115479 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0115024 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0114681 |
| LNPK | lunapark, ER junction formation factor | 0.0114139 |
| CCNL1 | cyclin L1 | 0.0113738 |
| RNF213 | ring finger protein 213 | 0.0113619 |
| RPS12 | ribosomal protein S12 | 0.0112916 |
| HELZ | helicase with zinc finger | 0.0111299 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0111272 |
| FBXO22 | F-box protein 22 | 0.0110915 |
| PKM | pyruvate kinase, muscle | 0.0109191 |
| CDK19 | cyclin-dependent kinase 19 | 0.0108605 |
| E2F7 | E2F transcription factor 7 | 0.0108382 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0107545 |
| RPS3 | ribosomal protein S3 | 0.0107006 |
| DGKH | diacylglycerol kinase, eta | 0.0106305 |
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 0.0105313 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.0104901 |
| TSGA10 | testis specific, 10 | 0.0104646 |
| FLNC | filamin C, gamma | 0.0104411 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0104034 |
| SECISBP2 | SECIS binding protein 2 | 0.0102832 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0102773 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0102085 |
| ANXA4 | annexin A4 | 0.0100901 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.393976 |
| EXT1 | exostosin glycosyltransferase 1 | -0.107622 |
| EFNA5 | ephrin-A5 | -0.103062 |
| ACTG1 | actin gamma 1 | -0.0895465 |
| GPC6 | glypican 6 | -0.0863542 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.082861 |
| DTNA | dystrobrevin, alpha | -0.081303 |
| ASPH | aspartate beta-hydroxylase | -0.0775022 |
| USP34 | ubiquitin specific peptidase 34 | -0.0739198 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0682098 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0605762 |
| JMJD1C | jumonji domain containing 1C | -0.0601613 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0591561 |
| CALD1 | caldesmon 1 | -0.0580993 |
| PTK2 | protein tyrosine kinase 2 | -0.0565672 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0523183 |
| RUNX1 | runt-related transcription factor 1 | -0.049694 |
| RPS6 | ribosomal protein S6 | -0.0489734 |
| NAV1 | neuron navigator 1 | -0.0475232 |
| RTN4 | reticulon 4 | -0.0472376 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0458724 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0456415 |
| ANO6 | anoctamin 6 | -0.0455828 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0416281 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0413869 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0409781 |
| LDHA | lactate dehydrogenase A | -0.0397658 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0393929 |
| NF1 | neurofibromin 1 | -0.0392823 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0387442 |
| MT2A | metallothionein 2A | -0.0377688 |
| SMYD3 | SET and MYND domain containing 3 | -0.0371926 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0371079 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0368604 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0367209 |
| RPS2 | ribosomal protein S2 | -0.0364718 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.036229 |
| POTEF | POTE ankyrin domain family, member F | -0.0360933 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0353006 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0350833 |
| SBF2 | SET binding factor 2 | -0.0345302 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.034492 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0344339 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0341341 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0336988 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0334532 |
| ERBIN | erbb2 interacting protein | -0.0332396 |
| CDK6 | cyclin-dependent kinase 6 | -0.0331579 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0328323 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0327518 |
| KIAA1549L | KIAA1549-like | -0.0325966 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0325764 |
| TMPRSS15 | transmembrane protease, serine 15 | -0.0324182 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0318973 |
| FOXP1 | forkhead box P1 | -0.0315778 |
| TXNRD1 | thioredoxin reductase 1 | -0.0313509 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0311142 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0303944 |
| FTL | ferritin, light polypeptide | -0.0303227 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0301669 |
| FRMD6 | FERM domain containing 6 | -0.030004 |
| BRD2 | bromodomain containing 2 | -0.029638 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0294535 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0294366 |
| ZNF292 | zinc finger protein 292 | -0.0293658 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0292195 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0286931 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0285434 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0285331 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0283809 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0282753 |
| RPS25 | ribosomal protein S25 | -0.0282521 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.028224 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0281533 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0280245 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0279982 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0278093 |
| CD44 | CD44 molecule (Indian blood group) | -0.0276815 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0276472 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0274096 |
| TXNIP | thioredoxin interacting protein | -0.0269539 |
| RPS23 | ribosomal protein S23 | -0.0268606 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0268046 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0267209 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0259636 |
| SP100 | SP100 nuclear antigen | -0.0259295 |
| NABP1 | nucleic acid binding protein 1 | -0.0257234 |
| CFAP251 | cilia and flagella associated protein 251 | -0.0256334 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0255442 |
| VCL | vinculin | -0.0255182 |
| ATXN1 | ataxin 1 | -0.0251485 |
| RPL38 | ribosomal protein L38 | -0.0251271 |
| NBAS | neuroblastoma amplified sequence | -0.025118 |
| VIM | vimentin | -0.0251031 |
| CCDC91 | coiled-coil domain containing 91 | -0.0250075 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0249445 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0243642 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0242197 |
| DST | dystonin | -0.0242019 |
| BPTF | bromodomain PHD finger transcription factor | -0.0240833 |
