| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxorubicin (hydrochloride) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Doxorubicin (hydrochloride)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.150385 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.116896 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.093229 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0723353 |
| CANX | calnexin | 0.0716173 |
| GDF15 | growth differentiation factor 15 | 0.0519791 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0518772 |
| PCBP2 | poly(rC) binding protein 2 | 0.0499356 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0479825 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0457194 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0446134 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0418691 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0416244 |
| HDLBP | high density lipoprotein binding protein | 0.040366 |
| BRD2 | bromodomain containing 2 | 0.0395448 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0388566 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0386614 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0382095 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0380407 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0376709 |
| MED13L | mediator complex subunit 13-like | 0.0360919 |
| PLK2 | polo-like kinase 2 | 0.0360353 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0359396 |
| LRRC1 | leucine rich repeat containing 1 | 0.0352379 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0337754 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0334859 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0317753 |
| YBX3 | Y box binding protein 3 | 0.0315141 |
| MYO6 | myosin VI | 0.0312556 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0312478 |
| POLH | polymerase (DNA directed), eta | 0.0299194 |
| SRPK2 | SRSF protein kinase 2 | 0.0299016 |
| MLEC | malectin | 0.0296548 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0293678 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0292587 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.029061 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0289965 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0286003 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0284434 |
| ATF3 | activating transcription factor 3 | 0.0283982 |
| ASTN2 | astrotactin 2 | 0.0283503 |
| MORF4L2 | mortality factor 4 like 2 | 0.0282315 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0279334 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0277738 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0274645 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.027453 |
| OGA | O-GlcNAcase | 0.0271186 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0269864 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0269234 |
| NDRG1 | N-myc downstream regulated 1 | 0.0268214 |
| LRRC23 | leucine rich repeat containing 23 | 0.0263311 |
| FRMD5 | FERM domain containing 5 | 0.0262763 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0261758 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0260405 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0258571 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.025842 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0255978 |
| SMAD3 | SMAD family member 3 | 0.0253431 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0252552 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.025179 |
| GOLGA4 | golgin A4 | 0.0251615 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0250748 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0250013 |
| SRP54 | signal recognition particle 54kDa | 0.0249482 |
| CALR | calreticulin | 0.0242342 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0237728 |
| SQSTM1 | sequestosome 1 | 0.0235271 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0233997 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0233065 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.023306 |
| FBXO22 | F-box protein 22 | 0.0232515 |
| FUS | FUS RNA binding protein | 0.023179 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0231523 |
| GOLGB1 | golgin B1 | 0.0231156 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0228429 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0227587 |
| RPL3 | ribosomal protein L3 | 0.0222422 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0221819 |
| XPO1 | exportin 1 | 0.0221502 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0220997 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0219406 |
| UBC | ubiquitin C | 0.0218395 |
| KIF26B | kinesin family member 26B | 0.0217998 |
| INTS6 | integrator complex subunit 6 | 0.0217426 |
| STK17A | serine/threonine kinase 17a | 0.0217163 |
| HLA-E | major histocompatibility complex, class I, E | 0.0216929 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0214811 |
| CLTC | clathrin, heavy chain (Hc) | 0.0213464 |
| SPAG9 | sperm associated antigen 9 | 0.0211024 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0208923 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0208732 |
| APAF1 | apoptotic peptidase activating factor 1 | 0.0207319 |
| IRF1 | interferon regulatory factor 1 | 0.0206954 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0205021 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.020383 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.020369 |
| SUCO | SUN domain containing ossification factor | 0.0203019 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.0200247 |
| HBP1 | HMG-box transcription factor 1 | 0.0199893 |
| FMNL2 | formin-like 2 | 0.0199517 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.165262 |
| FLNB | filamin B, beta | -0.137688 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.122182 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0983841 |
| PKP2 | plakophilin 2 | -0.0938639 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.086207 |
| PRSS3 | protease, serine, 3 | -0.0860058 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0851203 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0815751 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0771022 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0741626 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0740687 |
| ABHD17C | abhydrolase domain containing 17C | -0.0740056 |
| ITGA6 | integrin, alpha 6 | -0.0705172 |
| MYO1E | myosin IE | -0.0703049 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0692985 |
| FOXO1 | forkhead box O1 | -0.06868 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0665129 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0646407 |
| FOXP1 | forkhead box P1 | -0.0623974 |
| RPS6 | ribosomal protein S6 | -0.0607233 |
| PLAC8 | placenta-specific 8 | -0.0597697 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0592066 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.059149 |
| VCL | vinculin | -0.0586773 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0575483 |
| ANXA11 | annexin A11 | -0.0574526 |
| MX1 | MX dynamin-like GTPase 1 | -0.0543475 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0529536 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0519258 |
| TRIM2 | tripartite motif containing 2 | -0.0518309 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0516863 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0516321 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0511646 |
| PRELID2 | PRELI domain containing 2 | -0.0509202 |
| PCDHB16 | protocadherin beta 16 | -0.0500463 |
| ANXA2 | annexin A2 | -0.0497019 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0492082 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0483302 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0478967 |
| MYOF | myoferlin | -0.0478496 |
| SPON1 | spondin 1, extracellular matrix protein | -0.0464511 |
| TSPAN8 | tetraspanin 8 | -0.0463581 |
| SH3RF2 | SH3 domain containing ring finger 2 | -0.0455872 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0455582 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0439081 |
| KRT8 | keratin 8, type II | -0.0422464 |
| RPL35A | ribosomal protein L35a | -0.0420387 |
| RPS12 | ribosomal protein S12 | -0.0406559 |
| RPL9 | ribosomal protein L9 | -0.0404406 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0403689 |
| WWC1 | WW and C2 domain containing 1 | -0.0402765 |
| CALB1 | calbindin 1, 28kDa | -0.040005 |
| RAD51B | RAD51 paralog B | -0.0396748 |
| MYO1D | myosin ID | -0.0387627 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0384161 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0384134 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0383944 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0382796 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0374123 |
| FERMT1 | fermitin family member 1 | -0.0359854 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.035846 |
| TXNRD1 | thioredoxin reductase 1 | -0.035369 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0350496 |
| RPL37A | ribosomal protein L37a | -0.035043 |
| PLSCR1 | phospholipid scramblase 1 | -0.0347454 |
| RPS17 | ribosomal protein S17 | -0.0346709 |
| KLF6 | Kruppel-like factor 6 | -0.0346665 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0341728 |
| TLN2 | talin 2 | -0.0341597 |
| ACTN4 | actinin, alpha 4 | -0.0335235 |
| RIGI | RNA sensor RIG-I | -0.0334459 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0329055 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0327322 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.032487 |
| SP100 | SP100 nuclear antigen | -0.0322888 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.032149 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.031523 |
| MX2 | MX dynamin-like GTPase 2 | -0.0307761 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0305875 |
| EXOC4 | exocyst complex component 4 | -0.0304971 |
| RPLP2 | ribosomal protein, large, P2 | -0.0302655 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.030037 |
| SNX9 | sorting nexin 9 | -0.0299803 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.029953 |
| CENPF | centromere protein F, 350/400kDa | -0.0296333 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.029555 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0292457 |
| WWOX | WW domain containing oxidoreductase | -0.029243 |
| TPM1 | tropomyosin 1 (alpha) | -0.0290159 |
| RPS3 | ribosomal protein S3 | -0.0288379 |
| RPLP1 | ribosomal protein, large, P1 | -0.0287377 |
| PDE8A | phosphodiesterase 8A | -0.0286617 |
| RPS27A | ribosomal protein S27a | -0.0285561 |
| LAMA4 | laminin, alpha 4 | -0.0285339 |
| ATP10B | ATPase, class V, type 10B | -0.0283667 |
| FHIT | fragile histidine triad | -0.0283614 |
| BCL2L1 | BCL2-like 1 | -0.0278549 |
| ABHD2 | abhydrolase domain containing 2 | -0.0278151 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0274969 |
