| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxorubicin (hydrochloride) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Doxorubicin (hydrochloride)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.0940952 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0937827 |
| FN1 | fibronectin 1 | 0.0891039 |
| PCBP2 | poly(rC) binding protein 2 | 0.0806656 |
| CCNL1 | cyclin L1 | 0.0778231 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0750761 |
| VEGFA | vascular endothelial growth factor A | 0.0633594 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0630558 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.059412 |
| NDRG1 | N-myc downstream regulated 1 | 0.0570113 |
| POTEF | POTE ankyrin domain family, member F | 0.0553587 |
| TPM3 | tropomyosin 3 | 0.0545119 |
| MSN | moesin | 0.0521827 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0474875 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0440387 |
| CALR | calreticulin | 0.0431375 |
| ARRDC3 | arrestin domain containing 3 | 0.0376608 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0366247 |
| RPSA | ribosomal protein SA | 0.0355337 |
| YTHDC1 | YTH domain containing 1 | 0.0354172 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0349836 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0334549 |
| HDGF | hepatoma-derived growth factor | 0.0330689 |
| PLAU | plasminogen activator, urokinase | 0.032462 |
| PKM | pyruvate kinase, muscle | 0.0319621 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0305606 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.029457 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0270678 |
| NUP58 | nucleoporin 58 | 0.027057 |
| RNF145 | ring finger protein 145 | 0.0267654 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0263942 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0262309 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0262221 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0261299 |
| CANX | calnexin | 0.0260151 |
| MYO6 | myosin VI | 0.0260122 |
| IRF6 | interferon regulatory factor 6 | 0.0257502 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0251327 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0251016 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0249169 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.023802 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0237647 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0237402 |
| PLEC | plectin | 0.0235699 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.023479 |
| RPL3 | ribosomal protein L3 | 0.0233292 |
| FLNA | filamin A, alpha | 0.0231418 |
| TOP1 | topoisomerase (DNA) I | 0.0223254 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0221344 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0220597 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0215277 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0210032 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0206117 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0201009 |
| DSPP | dentin sialophosphoprotein | 0.0197853 |
| MCL1 | myeloid cell leukemia 1 | 0.0195523 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0192966 |
| SET | SET nuclear proto-oncogene | 0.0192258 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0185342 |
| TSPAN15 | tetraspanin 15 | 0.0185272 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0184843 |
| RNF213 | ring finger protein 213 | 0.0184105 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0179978 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0178573 |
| LDHA | lactate dehydrogenase A | 0.0178474 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0178244 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0176749 |
| PNN | pinin, desmosome associated protein | 0.0172399 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0172246 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0172137 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | 0.0171414 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0169695 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0169414 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0169219 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0169174 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0169108 |
| NCKAP1 | NCK-associated protein 1 | 0.0168735 |
| DIAPH1 | diaphanous-related formin 1 | 0.0168329 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0166486 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0157363 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0156445 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0153534 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0152496 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0150994 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0149281 |
| DTNA | dystrobrevin, alpha | 0.0148865 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0147561 |
| ECT2 | epithelial cell transforming 2 | 0.0146732 |
| HSPA1B | heat shock 70kDa protein 1B | 0.0146029 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0145164 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0144996 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.014455 |
| PAPOLA | poly(A) polymerase alpha | 0.0143339 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0143146 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0142853 |
| APP | amyloid beta (A4) precursor protein | 0.0141884 |
| XPOT | exportin, tRNA | 0.014051 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0136979 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0135609 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0135003 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.270989 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.198503 |
| ACTG1 | actin gamma 1 | -0.195824 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.182921 |
| FTL | ferritin, light polypeptide | -0.170137 |
| TMSB10 | thymosin beta 10 | -0.116724 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.114523 |
| PTMA | prothymosin, alpha | -0.0913593 |
| S100A6 | S100 calcium binding protein A6 | -0.0893986 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0721516 |
| RPL35A | ribosomal protein L35a | -0.0713225 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0709607 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0692954 |
| RPL34 | ribosomal protein L34 | -0.0691914 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0677492 |
| LAMB3 | laminin, beta 3 | -0.0672416 |
| LMO7 | LIM domain 7 | -0.0656171 |
| S100A10 | S100 calcium binding protein A10 | -0.0642334 |
| MT2A | metallothionein 2A | -0.0630261 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0618764 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0609561 |
| RPLP1 | ribosomal protein, large, P1 | -0.0574626 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0515941 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0514594 |
| RPL23 | ribosomal protein L23 | -0.0492263 |
| AHNAK | AHNAK nucleoprotein | -0.0477185 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0467526 |
| CD2AP | CD2-associated protein | -0.0463649 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0462992 |
| RPS8 | ribosomal protein S8 | -0.0460383 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0454734 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.045264 |
| RPS24 | ribosomal protein S24 | -0.0452231 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0445367 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0444909 |
| GNAS | GNAS complex locus | -0.0443513 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0441975 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0437206 |
| EFNA5 | ephrin-A5 | -0.0422918 |
| CSTB | cystatin B (stefin B) | -0.0422495 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0420307 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0419683 |
| RPS19 | ribosomal protein S19 | -0.0410296 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0399927 |
| RACK1 | receptor for activated C kinase 1 | -0.0399824 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0398559 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0394432 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0381306 |
| RPS23 | ribosomal protein S23 | -0.0380487 |
| TMEM263 | transmembrane protein 263 | -0.0377092 |
| RPL32 | ribosomal protein L32 | -0.0375885 |
| CDCP1 | CUB domain containing protein 1 | -0.036866 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0368156 |
| RPS29 | ribosomal protein S29 | -0.0366713 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0365019 |
| SDC4 | syndecan 4 | -0.0358344 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0356755 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0354563 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0348314 |
| RPL12 | ribosomal protein L12 | -0.0348028 |
| NAV2 | neuron navigator 2 | -0.034604 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0345503 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0344589 |
| LAMC2 | laminin, gamma 2 | -0.0342877 |
| RPS27A | ribosomal protein S27a | -0.0340176 |
| RPL30 | ribosomal protein L30 | -0.03391 |
| RRBP1 | ribosome binding protein 1 | -0.0337814 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0337049 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0334486 |
| LOC112694756 | uncharaterized LOC112694756 | -0.032943 |
| RPLP2 | ribosomal protein, large, P2 | -0.03281 |
| ARF1 | ADP-ribosylation factor 1 | -0.0326825 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0326404 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0324331 |
| LMNA | lamin A/C | -0.0322266 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0320336 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0319622 |
| RPLP0 | ribosomal protein, large, P0 | -0.0319621 |
| ANXA2 | annexin A2 | -0.0319241 |
| RPL11 | ribosomal protein L11 | -0.0318173 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0317828 |
| RPS6 | ribosomal protein S6 | -0.0315765 |
| TMSB4X | thymosin beta 4, X-linked | -0.0310988 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0310842 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0306826 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0306185 |
| RPL19 | ribosomal protein L19 | -0.0304235 |
| PLSCR1 | phospholipid scramblase 1 | -0.0302691 |
| ENO1 | enolase 1, (alpha) | -0.0299096 |
| RPL27A | ribosomal protein L27a | -0.0296493 |
| KLF6 | Kruppel-like factor 6 | -0.0296121 |
| CD63 | CD63 molecule | -0.0296114 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.029579 |
| KRT7 | keratin 7, type II | -0.0294465 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0293911 |
| RPL9 | ribosomal protein L9 | -0.029368 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0291264 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0291213 |
| RPS21 | ribosomal protein S21 | -0.029101 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0289631 |
