| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxorubicin (hydrochloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Doxorubicin (hydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0661391 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.062022 |
| CENPF | centromere protein F, 350/400kDa | 0.0605195 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0563245 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0487834 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0451388 |
| PGK1 | phosphoglycerate kinase 1 | 0.0421898 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0420283 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.042027 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.0415172 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0411396 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0402139 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0399497 |
| ZNF292 | zinc finger protein 292 | 0.0398795 |
| ANLN | anillin, actin binding protein | 0.0396855 |
| PCBP2 | poly(rC) binding protein 2 | 0.0385822 |
| OGA | O-GlcNAcase | 0.0366775 |
| TPX2 | TPX2, microtubule-associated | 0.0352296 |
| XPO1 | exportin 1 | 0.0344093 |
| DIAPH3 | diaphanous-related formin 3 | 0.0335006 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0333366 |
| CCNL1 | cyclin L1 | 0.0329785 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0324292 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0322871 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0322636 |
| RBM39 | RNA binding motif protein 39 | 0.0317323 |
| MKI67 | marker of proliferation Ki-67 | 0.0316764 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0314213 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0310626 |
| NUP58 | nucleoporin 58 | 0.0305776 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0305609 |
| ECT2 | epithelial cell transforming 2 | 0.0297196 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0286123 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0284223 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.028404 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0278814 |
| HELZ | helicase with zinc finger | 0.0278575 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.027675 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0275022 |
| HMGB2 | high mobility group box 2 | 0.0274608 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0271046 |
| ZNF148 | zinc finger protein 148 | 0.026899 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0268044 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0264112 |
| PKM | pyruvate kinase, muscle | 0.0263736 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0262654 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0261427 |
| TFG | TRK-fused gene | 0.0261426 |
| KIF5B | kinesin family member 5B | 0.026031 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0257745 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0256951 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0247751 |
| RAB8B | RAB8B, member RAS oncogene family | 0.024739 |
| SGO2 | shugoshin 2 | 0.024545 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0245255 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0245074 |
| NOP58 | NOP58 ribonucleoprotein | 0.0244373 |
| FLNA | filamin A, alpha | 0.0240405 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0239586 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0236404 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0231499 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0231004 |
| CD109 | CD109 molecule | 0.022975 |
| TTK | TTK protein kinase | 0.0229264 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0227672 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0227179 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.022717 |
| NEK7 | NIMA-related kinase 7 | 0.0226725 |
| MEIS2 | Meis homeobox 2 | 0.0226358 |
| MATR3 | matrin 3 | 0.0225893 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0225749 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.022466 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0223764 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0223433 |
| SUCO | SUN domain containing ossification factor | 0.0222116 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0222039 |
| NPTN | neuroplastin | 0.022148 |
| NCKAP1 | NCK-associated protein 1 | 0.021829 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0218016 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0216995 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0216444 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0214387 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0213334 |
| USP37 | ubiquitin specific peptidase 37 | 0.0212955 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0212761 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0211301 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0210761 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.020863 |
| YTHDC1 | YTH domain containing 1 | 0.0207493 |
| USP3 | ubiquitin specific peptidase 3 | 0.0207444 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0206662 |
| KIF4A | kinesin family member 4A | 0.0206485 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0205771 |
| NAV2 | neuron navigator 2 | 0.020197 |
| ZNF654 | zinc finger protein 654 | 0.0201288 |
| SPAG9 | sperm associated antigen 9 | 0.02012 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0199742 |
| YME1L1 | YME1-like 1 ATPase | 0.0197509 |
| WDR43 | WD repeat domain 43 | 0.0196784 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0194131 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.160136 |
| VIM | vimentin | -0.132903 |
| HLA-B | major histocompatibility complex, class I, B | -0.129404 |
| B2M | beta-2-microglobulin | -0.117479 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.113799 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109637 |
| COL1A1 | collagen, type I, alpha 1 | -0.106323 |
| FTL | ferritin, light polypeptide | -0.101704 |
| COL1A2 | collagen, type I, alpha 2 | -0.0946024 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0760286 |
| TMSB10 | thymosin beta 10 | -0.0690186 |
| CDH13 | cadherin 13 | -0.0670902 |
| FRMD4A | FERM domain containing 4A | -0.0656589 |
| NAV1 | neuron navigator 1 | -0.0656136 |
| MT2A | metallothionein 2A | -0.0603476 |
| SP100 | SP100 nuclear antigen | -0.0586419 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0582924 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0575608 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0566317 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0554019 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0545053 |
| NRP1 | neuropilin 1 | -0.0489609 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0473565 |
| COL5A1 | collagen, type V, alpha 1 | -0.0468918 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0449509 |
| HLA-A | major histocompatibility complex, class I, A | -0.0439115 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0439102 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0439087 |
| TPM1 | tropomyosin 1 (alpha) | -0.0429653 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0427423 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0426917 |
| FAM20C | family with sequence similarity 20, member C | -0.0425185 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.042442 |
| INHBA | inhibin, beta A | -0.0420261 |
| EGR1 | early growth response 1 | -0.0404668 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0403847 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0393045 |
| TMEM178B | transmembrane protein 178B | -0.0391464 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0385336 |
| GLIS3 | GLIS family zinc finger 3 | -0.0377549 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0374548 |
| MTSS1 | metastasis suppressor 1 | -0.0374353 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0373935 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0371463 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0370005 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0369096 |
| IER3 | immediate early response 3 | -0.0365456 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0362848 |
| RAI14 | retinoic acid induced 14 | -0.0360268 |
| IL1B | interleukin 1, beta | -0.0358937 |
| ENO1 | enolase 1, (alpha) | -0.0356542 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0356344 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0345034 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.033623 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.032806 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0325141 |
| FHIT | fragile histidine triad | -0.03237 |
| RPL35A | ribosomal protein L35a | -0.0311293 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0311076 |
| TNS3 | tensin 3 | -0.0310289 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0310116 |
| ACTG1 | actin gamma 1 | -0.0309368 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0308579 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0306658 |
| TPM4 | tropomyosin 4 | -0.0298678 |
| TNNC1 | troponin C type 1 (slow) | -0.0297851 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0285825 |
| HLA-C | major histocompatibility complex, class I, C | -0.0284929 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0280959 |
| HDAC9 | histone deacetylase 9 | -0.0279231 |
| PCBP3 | poly(rC) binding protein 3 | -0.0277127 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0272578 |
| MMP12 | matrix metallopeptidase 12 | -0.0265456 |
| COL5A3 | collagen, type V, alpha 3 | -0.0259787 |
| RPLP1 | ribosomal protein, large, P1 | -0.0259698 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0254091 |
| STC1 | stanniocalcin 1 | -0.025403 |
| S100A9 | S100 calcium binding protein A9 | -0.0252969 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0249963 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0247509 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0245765 |
| S100A6 | S100 calcium binding protein A6 | -0.0242749 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.024008 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.023574 |
| ASPH | aspartate beta-hydroxylase | -0.0235393 |
| LOXL2 | lysyl oxidase-like 2 | -0.0235288 |
| HPCAL1 | hippocalcin-like 1 | -0.0234454 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0230905 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0230026 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0224387 |
| RRBP1 | ribosome binding protein 1 | -0.0221695 |
| RPS19 | ribosomal protein S19 | -0.0220464 |
| PTMA | prothymosin, alpha | -0.0218016 |
| XAF1 | XIAP associated factor 1 | -0.021691 |
| IFI44L | interferon-induced protein 44-like | -0.0214933 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0214213 |
| CA12 | carbonic anhydrase XII | -0.0213654 |
| ANGPTL4 | angiopoietin-like 4 | -0.0212119 |
| RPS8 | ribosomal protein S8 | -0.0211673 |
| DST | dystonin | -0.0211549 |
