| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxorubicin (hydrochloride) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Doxorubicin (hydrochloride)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TENM1 | teneurin transmembrane protein 1 | 0.0807844 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0775531 |
| CENPF | centromere protein F, 350/400kDa | 0.0618936 |
| PDE10A | phosphodiesterase 10A | 0.0488683 |
| PEG10 | paternally expressed 10 | 0.0403225 |
| PCM1 | pericentriolar material 1 | 0.0373155 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0358576 |
| TXNRD1 | thioredoxin reductase 1 | 0.0349651 |
| MKI67 | marker of proliferation Ki-67 | 0.032128 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0319876 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0307222 |
| ECT2 | epithelial cell transforming 2 | 0.0306859 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0284116 |
| XPO1 | exportin 1 | 0.0272129 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0270134 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0269905 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0267753 |
| MATR3 | matrin 3 | 0.0259886 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0259436 |
| NUF2 | NUF2, NDC80 kinetochore complex component | 0.0255792 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0251906 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0250565 |
| CADM1 | cell adhesion molecule 1 | 0.0245244 |
| SGO2 | shugoshin 2 | 0.0236147 |
| MYEF2 | myelin expression factor 2 | 0.0228556 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.022833 |
| MTMR7 | myotubularin related protein 7 | 0.0226788 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | 0.0225837 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0225744 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0224283 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0218246 |
| DIAPH3 | diaphanous-related formin 3 | 0.021795 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0216468 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0216165 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0214058 |
| TTK | TTK protein kinase | 0.0212295 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0209452 |
| AOPEP | aminopeptidase O (putative) | 0.0205873 |
| TPX2 | TPX2, microtubule-associated | 0.0204274 |
| RTN4 | reticulon 4 | 0.0202314 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0198962 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0194191 |
| SPAG5 | sperm associated antigen 5 | 0.0193667 |
| PBK | PDZ binding kinase | 0.0191032 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0190131 |
| CDCA2 | cell division cycle associated 2 | 0.0189981 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0188442 |
| KNL1 | kinetochore scaffold 1 | 0.0187965 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0187825 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0186946 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0185867 |
| ANLN | anillin, actin binding protein | 0.0185107 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0184511 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0183635 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0182452 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0180421 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0180199 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0179836 |
| KIF11 | kinesin family member 11 | 0.0179639 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0176349 |
| UBAC2 | UBA domain containing 2 | 0.0175064 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0173513 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0171702 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0171311 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0171278 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0169609 |
| H1-0 | H1.0 linker histone | 0.0169288 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0168983 |
| KIF5B | kinesin family member 5B | 0.0168514 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0163899 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0163398 |
| GRAMD4 | GRAM domain containing 4 | 0.016184 |
| PGK1 | phosphoglycerate kinase 1 | 0.0161503 |
| AURKA | aurora kinase A | 0.0160831 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0160671 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0159988 |
| CA8 | carbonic anhydrase VIII | 0.0155718 |
| ZNF292 | zinc finger protein 292 | 0.0155033 |
| CCDC88A | coiled-coil domain containing 88A | 0.0154442 |
| PCBP2 | poly(rC) binding protein 2 | 0.015415 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 0.0153762 |
| TUBA1B | tubulin, alpha 1b | 0.0152453 |
| NIPSNAP2 | nipsnap homolog 2 | 0.0152172 |
| PDS5B | PDS5 cohesin associated factor B | 0.0150334 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0149902 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0148651 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | 0.0148134 |
| NCKAP1 | NCK-associated protein 1 | 0.0147634 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.014739 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.014688 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0146078 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0145926 |
| MCM8 | minichromosome maintenance complex component 8 | 0.0145391 |
| TUBB | tubulin, beta class I | 0.0144279 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0142904 |
| PER1 | period circadian clock 1 | 0.0142618 |
| RGS3 | regulator of G-protein signaling 3 | 0.0142069 |
| NCAM1 | neural cell adhesion molecule 1 | 0.01407 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0140341 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.0140054 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GPC6 | glypican 6 | -0.181536 |
| NRG1 | neuregulin 1 | -0.11718 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.103811 |
| RORA | RAR-related orphan receptor A | -0.0942529 |
| MCL1 | myeloid cell leukemia 1 | -0.090892 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0783371 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0762419 |
| SNTG1 | syntrophin, gamma 1 | -0.0753795 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0745831 |
| STC1 | stanniocalcin 1 | -0.0670205 |
| RPL37A | ribosomal protein L37a | -0.0646998 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0598441 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0590289 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0590179 |
| SMYD3 | SET and MYND domain containing 3 | -0.0548699 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.052985 |
| EFNA5 | ephrin-A5 | -0.0503135 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0503027 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0494529 |
| KIF26B | kinesin family member 26B | -0.0474765 |
| RPS3 | ribosomal protein S3 | -0.0464872 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0445989 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0443721 |
| LSAMP | limbic system-associated membrane protein | -0.0442142 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0438442 |
| NDRG1 | N-myc downstream regulated 1 | -0.0438308 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0427808 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.042354 |
| PTCHD4 | patched domain containing 4 | -0.0421965 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0421139 |
| GPC5 | glypican 5 | -0.0416565 |
| PTMA | prothymosin, alpha | -0.0412294 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0409858 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0408962 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | -0.0400346 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0387074 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.0379531 |
| RPL37 | ribosomal protein L37 | -0.0370961 |
| RPLP1 | ribosomal protein, large, P1 | -0.036481 |
| RPS6 | ribosomal protein S6 | -0.0357369 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0356207 |
| CNTNAP2 | contactin associated protein-like 2 | -0.0351009 |
| KLHL29 | kelch-like family member 29 | -0.0349448 |
| CDK13 | cyclin-dependent kinase 13 | -0.0346273 |
| ESRRG | estrogen-related receptor gamma | -0.0343102 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.0341888 |
| EPHA6 | EPH receptor A6 | -0.0340609 |
| MAP1B | microtubule-associated protein 1B | -0.034047 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0337082 |
| MT2A | metallothionein 2A | -0.0336266 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0336152 |
| NBEA | neurobeachin | -0.0330034 |
| COL22A1 | collagen, type XXII, alpha 1 | -0.0329666 |
| RPL26 | ribosomal protein L26 | -0.0326402 |
| ACTG1 | actin gamma 1 | -0.0318851 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0314906 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.0309709 |
| CNKSR3 | CNKSR family member 3 | -0.0307853 |
| HOMER1 | homer scaffolding protein 1 | -0.0307783 |
| RPS8 | ribosomal protein S8 | -0.0299225 |
| RPS12 | ribosomal protein S12 | -0.0298771 |
| APP | amyloid beta (A4) precursor protein | -0.0297994 |
| VGF | VGF nerve growth factor inducible | -0.0295232 |
| NAV2 | neuron navigator 2 | -0.0293725 |
| TOP1 | topoisomerase (DNA) I | -0.0289295 |
| RPL11 | ribosomal protein L11 | -0.0286376 |
| SCG2 | secretogranin II | -0.0283871 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0280357 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.027959 |
| RPL31 | ribosomal protein L31 | -0.0278406 |
| SCFD1 | sec1 family domain containing 1 | -0.0277675 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0275856 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0274269 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0273273 |
| DENND4A | DENN/MADD domain containing 4A | -0.0273267 |
| FAM13A | family with sequence similarity 13, member A | -0.027188 |
| FTL | ferritin, light polypeptide | -0.0270829 |
| INHBA | inhibin, beta A | -0.0269959 |
| RPL30 | ribosomal protein L30 | -0.0267282 |
| ZFHX3 | zinc finger homeobox 3 | -0.0266905 |
| EGR1 | early growth response 1 | -0.0265121 |
| RPS27A | ribosomal protein S27a | -0.0264693 |
| NELL1 | NEL-like 1 (chicken) | -0.0261832 |
| RPS17 | ribosomal protein S17 | -0.0250998 |
| HM13 | histocompatibility (minor) 13 | -0.0250322 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0247346 |
| ASPH | aspartate beta-hydroxylase | -0.0243898 |
| RPS27 | ribosomal protein S27 | -0.0243153 |
| TMSB10 | thymosin beta 10 | -0.024097 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | -0.0236588 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.023174 |
| ARFGEF3 | ARFGEF family member 3 | -0.0230696 |
| RPL36 | ribosomal protein L36 | -0.022983 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.022861 |
| PAEP | progestagen-associated endometrial protein | -0.0228212 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0227162 |
| NANOS1 | nanos homolog 1 (Drosophila) | -0.0225825 |
| NCKAP5 | NCK-associated protein 5 | -0.0223398 |
| RACK1 | receptor for activated C kinase 1 | -0.02223 |
| ASIC2 | acid sensing (proton gated) ion channel 2 | -0.0220436 |
