| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxorubicin (hydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Doxorubicin (hydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.107615 |
| CADM1 | cell adhesion molecule 1 | 0.100136 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0851656 |
| FN1 | fibronectin 1 | 0.081045 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0796121 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0729597 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0608981 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0557465 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0539998 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0532679 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0523953 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0509889 |
| WTAP | Wilms tumor 1 associated protein | 0.0480646 |
| SMAD3 | SMAD family member 3 | 0.0462625 |
| FLNA | filamin A, alpha | 0.0453816 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0446641 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0434214 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0430344 |
| EFNA5 | ephrin-A5 | 0.0427492 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0415649 |
| OGA | O-GlcNAcase | 0.0411284 |
| SPAG9 | sperm associated antigen 9 | 0.0410475 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0404317 |
| AHR | aryl hydrocarbon receptor | 0.0404126 |
| FMNL2 | formin-like 2 | 0.0397288 |
| HELZ | helicase with zinc finger | 0.0395369 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0390743 |
| ATP13A3 | ATPase type 13A3 | 0.038529 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.037458 |
| SFTPA2 | surfactant protein A2 | 0.0369702 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.035978 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0359189 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0356801 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0354604 |
| MATR3 | matrin 3 | 0.0352266 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 | 0.0348672 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0348469 |
| KYNU | kynureninase | 0.0342941 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0332414 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0332207 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0331663 |
| PCBP2 | poly(rC) binding protein 2 | 0.0327872 |
| HLA-E | major histocompatibility complex, class I, E | 0.032234 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0317096 |
| USP37 | ubiquitin specific peptidase 37 | 0.0310417 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.030729 |
| TXNRD1 | thioredoxin reductase 1 | 0.0305935 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.030571 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0304408 |
| UBC | ubiquitin C | 0.0298784 |
| NEK7 | NIMA-related kinase 7 | 0.0293361 |
| ICAM1 | intercellular adhesion molecule 1 | 0.02922 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0291857 |
| SDC4 | syndecan 4 | 0.0286033 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0280086 |
| TMEM123 | transmembrane protein 123 | 0.0280017 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0275726 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0275407 |
| SLC35F3 | solute carrier family 35, member F3 | 0.027344 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0273036 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.02693 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.026922 |
| IPO7 | importin 7 | 0.0268788 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0259979 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0259388 |
| CCNL1 | cyclin L1 | 0.0258494 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0257633 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0250025 |
| FBXO42 | F-box protein 42 | 0.024739 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0246618 |
| HELLS | helicase, lymphoid-specific | 0.0245381 |
| CANX | calnexin | 0.0243096 |
| XPO1 | exportin 1 | 0.0239808 |
| ANLN | anillin, actin binding protein | 0.0239706 |
| TMEM178B | transmembrane protein 178B | 0.0239496 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0238366 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0237577 |
| IL6 | interleukin 6 | 0.0234837 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0232744 |
| GOLGA4 | golgin A4 | 0.0232527 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0231191 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | 0.0228979 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0226936 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0225821 |
| BRD2 | bromodomain containing 2 | 0.0225695 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0225385 |
| DIAPH3 | diaphanous-related formin 3 | 0.0223343 |
| HBS1L | HBS1-like translational GTPase | 0.0223067 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0222711 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0222537 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0221515 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0218161 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0216505 |
| OPTN | optineurin | 0.0214686 |
| ARRDC3 | arrestin domain containing 3 | 0.0214417 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0213272 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0212754 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0211148 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0210931 |
| SRGN | serglycin | 0.0210481 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.118299 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.102848 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0828254 |
| BICC1 | BicC family RNA binding protein 1 | -0.0795887 |
| VCAN | versican | -0.0763634 |
| MT2A | metallothionein 2A | -0.0679241 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0678771 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0676602 |
| VCL | vinculin | -0.0628195 |
| FRMD4A | FERM domain containing 4A | -0.0615631 |
| TMSB10 | thymosin beta 10 | -0.059745 |
| VIM | vimentin | -0.05643 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0532426 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0517139 |
| CENPF | centromere protein F, 350/400kDa | -0.0508152 |
| NAV1 | neuron navigator 1 | -0.0497528 |
| GLIS3 | GLIS family zinc finger 3 | -0.04935 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0490855 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0473216 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0472052 |
| ENO1 | enolase 1, (alpha) | -0.0455492 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0449967 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.044571 |
| EGR1 | early growth response 1 | -0.0442416 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0439504 |
| OSMR | oncostatin M receptor | -0.0439086 |
| NABP1 | nucleic acid binding protein 1 | -0.0438987 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0437628 |
| RIGI | RNA sensor RIG-I | -0.0429133 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0428232 |
| RPS12 | ribosomal protein S12 | -0.0425797 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0425719 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0413763 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0403097 |
| GPC6 | glypican 6 | -0.0401495 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0400764 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0384658 |
| RPL35A | ribosomal protein L35a | -0.0382916 |
| NDRG1 | N-myc downstream regulated 1 | -0.0381579 |
| MKI67 | marker of proliferation Ki-67 | -0.0379733 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0379704 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0377709 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0362402 |
| CD44 | CD44 molecule (Indian blood group) | -0.035488 |
| RAI14 | retinoic acid induced 14 | -0.0353951 |
| RPL37A | ribosomal protein L37a | -0.0352282 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0341585 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0334747 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0331378 |
| CLIC4 | chloride intracellular channel 4 | -0.0328495 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0318855 |
| SBF2 | SET binding factor 2 | -0.0318572 |
| LDHA | lactate dehydrogenase A | -0.0318395 |
| PLSCR1 | phospholipid scramblase 1 | -0.0313345 |
| CDCP1 | CUB domain containing protein 1 | -0.0313079 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0306513 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0303516 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0296457 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0295374 |
| SP100 | SP100 nuclear antigen | -0.0294568 |
| RTN4 | reticulon 4 | -0.0293245 |
| NAV2 | neuron navigator 2 | -0.0290999 |
| FAM20C | family with sequence similarity 20, member C | -0.0287231 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0284929 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0281619 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0277367 |
| MX1 | MX dynamin-like GTPase 1 | -0.0269594 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0256528 |
| MMP12 | matrix metallopeptidase 12 | -0.0251692 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.024883 |
| TNS3 | tensin 3 | -0.0248061 |
| HDAC8 | histone deacetylase 8 | -0.0247328 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0246122 |
| DIAPH2 | diaphanous-related formin 2 | -0.0243929 |
| HDAC9 | histone deacetylase 9 | -0.0242711 |
| LRRC7 | leucine rich repeat containing 7 | -0.0240942 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0237403 |
| RPL36 | ribosomal protein L36 | -0.0232936 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0232484 |
| PMP22 | peripheral myelin protein 22 | -0.0231402 |
| RPL35 | ribosomal protein L35 | -0.0218649 |
| PLIN2 | perilipin 2 | -0.0217711 |
| RPL26 | ribosomal protein L26 | -0.021431 |
| SMYD3 | SET and MYND domain containing 3 | -0.021383 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0212659 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0212044 |
| KLF6 | Kruppel-like factor 6 | -0.0211872 |
| JMJD1C | jumonji domain containing 1C | -0.0209821 |
| RPL9 | ribosomal protein L9 | -0.0208883 |
| TENM2 | teneurin transmembrane protein 2 | -0.0207392 |
| KIF4A | kinesin family member 4A | -0.020735 |
| FBXO11 | F-box protein 11 | -0.0206106 |
| STK17A | serine/threonine kinase 17a | -0.0203946 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0199201 |
| KRT19 | keratin 19, type I | -0.0196696 |
| RPS19 | ribosomal protein S19 | -0.0195651 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0194887 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0193686 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0193392 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0192809 |
