| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxorubicin (hydrochloride) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Doxorubicin (hydrochloride)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SDK1 | sidekick cell adhesion molecule 1 | 0.0671362 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0667689 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0642911 |
| INTS6 | integrator complex subunit 6 | 0.0635348 |
| CDH13 | cadherin 13 | 0.0527956 |
| NAV2 | neuron navigator 2 | 0.052709 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0522738 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0514712 |
| RAD51B | RAD51 paralog B | 0.0506542 |
| VCL | vinculin | 0.0496791 |
| PTMA | prothymosin, alpha | 0.0491726 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0429007 |
| UBAP2 | ubiquitin associated protein 2 | 0.0423208 |
| CCND1 | cyclin D1 | 0.0406798 |
| EXOC4 | exocyst complex component 4 | 0.0405824 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0395656 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0379906 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0349162 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0346101 |
| FLNA | filamin A, alpha | 0.0341913 |
| FRMD5 | FERM domain containing 5 | 0.0333805 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0323403 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0322374 |
| HSPA8 | heat shock 70kDa protein 8 | 0.032043 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0318551 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0316939 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0315493 |
| PRKCA | protein kinase C, alpha | 0.0311181 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.030721 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0304927 |
| PLEC | plectin | 0.0300002 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0294936 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0292833 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0291436 |
| KLHL29 | kelch-like family member 29 | 0.0279531 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0277791 |
| GPATCH2L | G patch domain containing 2-like | 0.0276487 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | 0.0271315 |
| GPHN | gephyrin | 0.02713 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0269574 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0266439 |
| DGKH | diacylglycerol kinase, eta | 0.0265613 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0265156 |
| NOP56 | NOP56 ribonucleoprotein | 0.0262773 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0261338 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0255675 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0254988 |
| CUX1 | cut-like homeobox 1 | 0.0252838 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0252384 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0250028 |
| SERINC5 | serine incorporator 5 | 0.0249713 |
| RCC1 | regulator of chromosome condensation 1 | 0.0248882 |
| HDAC4 | histone deacetylase 4 | 0.0248867 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0248632 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0247936 |
| RNF213 | ring finger protein 213 | 0.0247289 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0246894 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0245752 |
| TPP2 | tripeptidyl peptidase II | 0.0245614 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0244766 |
| CDK13 | cyclin-dependent kinase 13 | 0.0241929 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.023975 |
| HELLS | helicase, lymphoid-specific | 0.0239743 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.023911 |
| RRM2 | ribonucleotide reductase M2 | 0.0235967 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0235607 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0234292 |
| NHSL1 | NHS-like 1 | 0.0232717 |
| ASPH | aspartate beta-hydroxylase | 0.0232334 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0229865 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.0229464 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | 0.0229391 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0228892 |
| SRPK2 | SRSF protein kinase 2 | 0.0228498 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0225251 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0224856 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0224369 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0224158 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0223948 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | 0.0223589 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0223153 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.0222807 |
| EPHA4 | EPH receptor A4 | 0.0221621 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0221192 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0218329 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0215167 |
| FMNL2 | formin-like 2 | 0.0215006 |
| SQSTM1 | sequestosome 1 | 0.0214265 |
| DNHD1 | dynein heavy chain domain 1 | 0.0212401 |
| FUS | FUS RNA binding protein | 0.0211204 |
| CDK6 | cyclin-dependent kinase 6 | 0.02112 |
| SERPINA2 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) | 0.0210072 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0203112 |
| CEP128 | centrosomal protein 128kDa | 0.0200859 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0200474 |
| E2F3 | E2F transcription factor 3 | 0.0198547 |
| NDUFAF6 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 | 0.0197785 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0196847 |
| TULP4 | tubby like protein 4 | 0.0196429 |
| ABR | active BCR-related | 0.0194061 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.329899 |
| TMSB10 | thymosin beta 10 | -0.107665 |
| RPS6 | ribosomal protein S6 | -0.10397 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0938775 |
| MT2A | metallothionein 2A | -0.0843664 |
| EZR | ezrin | -0.0809518 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0767343 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.072404 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0668234 |
| PGK1 | phosphoglycerate kinase 1 | -0.066322 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0608449 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0606263 |
| RPL12 | ribosomal protein L12 | -0.0604918 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0593037 |
| ENO1 | enolase 1, (alpha) | -0.0561325 |
| RPLP1 | ribosomal protein, large, P1 | -0.055593 |
| EGR1 | early growth response 1 | -0.0555111 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0550465 |
| RPS19 | ribosomal protein S19 | -0.0542316 |
| RPS3 | ribosomal protein S3 | -0.0538975 |
| RPL23 | ribosomal protein L23 | -0.0520684 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.051987 |
| RPL18 | ribosomal protein L18 | -0.0516801 |
| TXNIP | thioredoxin interacting protein | -0.0503991 |
| GOLGA4 | golgin A4 | -0.0499386 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0493472 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0490937 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0476775 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0468667 |
| VIM | vimentin | -0.0467593 |
| ZNF292 | zinc finger protein 292 | -0.0466927 |
| RPL32 | ribosomal protein L32 | -0.045981 |
| RACK1 | receptor for activated C kinase 1 | -0.0455522 |
| RPL11 | ribosomal protein L11 | -0.0449468 |
| RPL19 | ribosomal protein L19 | -0.0445877 |
| RPLP0 | ribosomal protein, large, P0 | -0.0430304 |
| RPLP2 | ribosomal protein, large, P2 | -0.0428543 |
| RPL5 | ribosomal protein L5 | -0.0428442 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0422406 |
| RPS12 | ribosomal protein S12 | -0.0413742 |
| RPL35A | ribosomal protein L35a | -0.041024 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0409298 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0406264 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0397221 |
| OXR1 | oxidation resistance 1 | -0.0393894 |
| RPL36 | ribosomal protein L36 | -0.0388591 |
| ACTG1 | actin gamma 1 | -0.0387645 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0382097 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0382042 |
| RPS4X | ribosomal protein S4, X-linked | -0.0376806 |
| MT1X | metallothionein 1X | -0.0372569 |
| RPL7 | ribosomal protein L7 | -0.037037 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0368036 |
| SNX9 | sorting nexin 9 | -0.0366227 |
| CENPF | centromere protein F, 350/400kDa | -0.0364924 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0363569 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0351134 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0349176 |
| PFN1 | profilin 1 | -0.0345959 |
| SYT1 | synaptotagmin I | -0.034396 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0329705 |
| DUSP6 | dual specificity phosphatase 6 | -0.0326604 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0325634 |
| HMGA1 | high mobility group AT-hook 1 | -0.0321654 |
| ACTN4 | actinin, alpha 4 | -0.0319467 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0317738 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0315817 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.031276 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0311174 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0310584 |
| SBF2 | SET binding factor 2 | -0.0309221 |
| ANXA2 | annexin A2 | -0.0305266 |
| RPS23 | ribosomal protein S23 | -0.0303195 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0293576 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0291723 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0291117 |
| RPL34 | ribosomal protein L34 | -0.0290051 |
| RPS8 | ribosomal protein S8 | -0.0288374 |
| PERP | PERP, TP53 apoptosis effector | -0.0286354 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0284248 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0283011 |
| KLF6 | Kruppel-like factor 6 | -0.028259 |
| RPL28 | ribosomal protein L28 | -0.0281335 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0278725 |
| ITGA6 | integrin, alpha 6 | -0.0277498 |
| EMP1 | epithelial membrane protein 1 | -0.0274393 |
| SEC61G | Sec61 gamma subunit | -0.027399 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0271583 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0270745 |
| RPL35 | ribosomal protein L35 | -0.0270703 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0270521 |
| RPL26 | ribosomal protein L26 | -0.0269303 |
| KRT19 | keratin 19, type I | -0.0268802 |
| RUNX1 | runt-related transcription factor 1 | -0.0267763 |
| FOSL1 | FOS-like antigen 1 | -0.0267477 |
| MORF4L2 | mortality factor 4 like 2 | -0.0267427 |
| CDCP1 | CUB domain containing protein 1 | -0.0266915 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0265249 |
| ATXN1 | ataxin 1 | -0.0264983 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0264768 |
