| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Doxycycline (monohydrate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Doxycycline (monohydrate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PODXL | podocalyxin-like | 0.147824 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.131558 |
| COL5A1 | collagen, type V, alpha 1 | 0.104225 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0821691 |
| NAV1 | neuron navigator 1 | 0.0798344 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0784388 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0730244 |
| PLAT | plasminogen activator, tissue | 0.0726326 |
| POTEF | POTE ankyrin domain family, member F | 0.0577858 |
| SUCNR1 | succinate receptor 1 | 0.0547192 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0538261 |
| MAP1B | microtubule-associated protein 1B | 0.0521101 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0506036 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0456497 |
| FN1 | fibronectin 1 | 0.0448772 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0423804 |
| ATP13A3 | ATPase type 13A3 | 0.0413023 |
| CDH13 | cadherin 13 | 0.0397883 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0397176 |
| DST | dystonin | 0.0345369 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0340426 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0338405 |
| CYTH3 | cytohesin 3 | 0.0328774 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0327152 |
| MSN | moesin | 0.032521 |
| MSI2 | musashi RNA-binding protein 2 | 0.032455 |
| RUNX1 | runt-related transcription factor 1 | 0.032372 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0307646 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.029722 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0289883 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0286004 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0285765 |
| TAGLN2 | transgelin 2 | 0.0284463 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0271722 |
| FLNA | filamin A, alpha | 0.0268126 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0260847 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0256933 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0256049 |
| EFNA5 | ephrin-A5 | 0.0251761 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.0246385 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0246036 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0242686 |
| FLNB | filamin B, beta | 0.0241772 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0241349 |
| TPM3 | tropomyosin 3 | 0.0237722 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0236461 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0233266 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0230294 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0230034 |
| HDAC9 | histone deacetylase 9 | 0.0229525 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0228632 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0228288 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.022689 |
| PLXNA2 | plexin A2 | 0.0226269 |
| PKM | pyruvate kinase, muscle | 0.0222973 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0221825 |
| SEPTIN9 | septin 9 | 0.0221751 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0221469 |
| AUTS2 | autism susceptibility candidate 2 | 0.0219804 |
| NUP58 | nucleoporin 58 | 0.0217157 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0216445 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0213674 |
| TPM4 | tropomyosin 4 | 0.0213653 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0211128 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0209135 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0207032 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0206275 |
| VMP1 | vacuole membrane protein 1 | 0.0206087 |
| EGFR | epidermal growth factor receptor | 0.0204081 |
| NCKAP1 | NCK-associated protein 1 | 0.0202487 |
| GLIS3 | GLIS family zinc finger 3 | 0.0195969 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.019596 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0194859 |
| KRT81 | keratin 81, type II | 0.0192793 |
| CUX1 | cut-like homeobox 1 | 0.0190853 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.0187795 |
| RASAL2 | RAS protein activator like 2 | 0.0187596 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0185318 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0183535 |
| CEP170 | centrosomal protein 170kDa | 0.0182691 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0181671 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0181553 |
| IPO9 | importin 9 | 0.0180392 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0179296 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0179049 |
| APP | amyloid beta (A4) precursor protein | 0.0178621 |
| MCL1 | myeloid cell leukemia 1 | 0.0178019 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0176319 |
| AXL | AXL receptor tyrosine kinase | 0.0175127 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0174576 |
| ZNF638 | zinc finger protein 638 | 0.0173845 |
| COL6A1 | collagen, type VI, alpha 1 | 0.017377 |
| SRPK2 | SRSF protein kinase 2 | 0.0172259 |
| PLEC | plectin | 0.016837 |
| RAI14 | retinoic acid induced 14 | 0.016828 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0167612 |
| MED13L | mediator complex subunit 13-like | 0.0167479 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0166565 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0166027 |
| PRSS23 | protease, serine, 23 | 0.0164393 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.224329 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.219313 |
| MT2A | metallothionein 2A | -0.115665 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.109757 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0914862 |
| VIM | vimentin | -0.0852908 |
| UBC | ubiquitin C | -0.0750968 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0628965 |
| TMSB10 | thymosin beta 10 | -0.0619736 |
| CANX | calnexin | -0.0614846 |
| CSTB | cystatin B (stefin B) | -0.0614601 |
| AHNAK | AHNAK nucleoprotein | -0.0601945 |
| LOX | lysyl oxidase | -0.0573251 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0559951 |
| PTMA | prothymosin, alpha | -0.0515609 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0469035 |
| S100A10 | S100 calcium binding protein A10 | -0.0451263 |
| SQSTM1 | sequestosome 1 | -0.0450681 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0450374 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0426936 |
| HLA-B | major histocompatibility complex, class I, B | -0.0422083 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0419314 |
| FTL | ferritin, light polypeptide | -0.0383645 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0376979 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0349641 |
| S100A6 | S100 calcium binding protein A6 | -0.034071 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0340433 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0335866 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0333163 |
| ANXA2 | annexin A2 | -0.0329341 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0329252 |
| OGA | O-GlcNAcase | -0.0314752 |
| TMSB4X | thymosin beta 4, X-linked | -0.0314682 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0311799 |
| CAVIN1 | caveolae associated protein 1 | -0.0308166 |
| IER3 | immediate early response 3 | -0.0289688 |
| RPLP1 | ribosomal protein, large, P1 | -0.0289093 |
| LOXL2 | lysyl oxidase-like 2 | -0.0278611 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0275609 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0272238 |
| B2M | beta-2-microglobulin | -0.0268155 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0266294 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0266231 |
| HLA-E | major histocompatibility complex, class I, E | -0.0263172 |
| STC1 | stanniocalcin 1 | -0.026177 |
| ADM | adrenomedullin | -0.0241057 |
| RPL23 | ribosomal protein L23 | -0.0236342 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0233551 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0233251 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0232362 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0230423 |
| CD44 | CD44 molecule (Indian blood group) | -0.0227982 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0227222 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0224635 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0221099 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0217262 |
| CCND1 | cyclin D1 | -0.0211927 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0208125 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0205795 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0203652 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0202173 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.019998 |
| COL1A2 | collagen, type I, alpha 2 | -0.0194862 |
| RPL36 | ribosomal protein L36 | -0.0194261 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0191855 |
| RPL35A | ribosomal protein L35a | -0.0190145 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0187989 |
| HLA-C | major histocompatibility complex, class I, C | -0.018553 |
| RPS5 | ribosomal protein S5 | -0.0184279 |
| TXNIP | thioredoxin interacting protein | -0.0183381 |
| WTAP | Wilms tumor 1 associated protein | -0.0183115 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0180788 |
| RPL34 | ribosomal protein L34 | -0.01803 |
| KIAA1217 | KIAA1217 | -0.0177049 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0176961 |
| THBS2 | thrombospondin 2 | -0.0176653 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0175714 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0175674 |
| MMP12 | matrix metallopeptidase 12 | -0.0175109 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0174974 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0174728 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0172089 |
| MT1X | metallothionein 1X | -0.0171698 |
| CERT1 | ceramide transporter 1 | -0.017099 |
| RPS24 | ribosomal protein S24 | -0.0170861 |
| RPS6 | ribosomal protein S6 | -0.0170438 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0167194 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0167162 |
| TUBB | tubulin, beta class I | -0.0167026 |
| GNAS | GNAS complex locus | -0.0166833 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0166506 |
| BPTF | bromodomain PHD finger transcription factor | -0.0165894 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.016416 |
| FBXO11 | F-box protein 11 | -0.0163166 |
| RPL26 | ribosomal protein L26 | -0.0162886 |
| FAM107B | family with sequence similarity 107, member B | -0.0161032 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0160828 |
| TMEM263 | transmembrane protein 263 | -0.0160528 |
| RPS19 | ribosomal protein S19 | -0.0160312 |
| RPL19 | ribosomal protein L19 | -0.0160149 |
